The impact of protein concentration on mannitol and sodium chloride crystallinity and polymorphism upon lyophilization

Journal of Pharmaceutical Sciences

Volumn 98, Issue 9, 2009, Pages 3419-3429

  Dixon, Daniel ^a   Tchessalov, Serguei ^a   Barry, Anthony ^a   Warne, Nicholas ^a  

^a PFIZER INC   (United States)

Author keywords

Excipients; Freeze drying; Lyophilization; Polymorphism; Protein formulation; X ray powder diffractometry

Indexed keywords

HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; MANNITOL; PROTEIN; SODIUM CHLORIDE;

ARTICLE; CONCENTRATION RESPONSE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; FREEZE DRYING; MOISTURE; MOLECULAR WEIGHT; QUANTITATIVE ANALYSIS; X RAY DIFFRACTION;

EID: 63949086246     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21537     Document Type: Article

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