Induced expression of the IER5 gene by γ-ray irradiation and its involvement in cell cycle checkpoint control and survival

Radiation and Environmental Biophysics

Volumn 48, Issue 2, 2009, Pages 205-213

  Ding, Ku Ke ^a   Shang, Zeng Fu ^b   Hao, Chuan ^b,c   Xu, Qin Zhi ^b   Shen, Jing Jing ^a   Yang, Chuan Jie ^c   Xie, Yue Hua ^b   Qiao, Cha ^b,c   Wang, Yu ^b   Xu, Li Li ^a   Zhou, Ping Kun ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLES; CELL LINES; CONTROL LEVELS; HELA CELLS; HIGH DOSE; IN CELLS; MICROARRAY ANALYSIS; MRNA LEVELS; POST IRRADIATIONS; QUANTITATIVE REAL-TIME PCR; RADIATION DOSE; RADIORESISTANCE; RNA INTERFERENCES; S-PHASE; SHORT PERIODS; SURVIVAL ANALYSIS;

CELL CULTURE; GENETIC ENGINEERING; GROWTH KINETICS; IONIZING RADIATION; IRRADIATION; NUCLEIC ACIDS; POLARIZATION; RNA; SECURITY OF DATA;

CELL GROWTH;

MESSENGER RNA;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GAMMA RADIATION; GENE; GENE EXPRESSION; GENE REPRESSION; HELA CELL; HUMAN; HUMAN CELL; IMMEDIATE EARLY RESPONSE GENE 5; IONIZING RADIATION; IRRADIATION; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIOSENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

CELL CYCLE; CELL LINE; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; FLOW CYTOMETRY; GAMMA RAYS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; IMMEDIATE-EARLY PROTEINS; LYMPHOCYTES; NUCLEAR PROTEINS; RADIATION TOLERANCE; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION;

EID: 63949086075     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00411-009-0213-4     Document Type: Article

References (24)

1. MM Ahmed K Venkatasubbarao SM Fruitwala S Muthukkumar DP Wood Jr SF Sells M Mohiuddin VM Rangnekar 1996 EGR-1 induction is required for maximal radiosensitivity in A375-C6 melanoma cells J Biol Chem 271 29231 29292
2. SA Amundson 2008 Functional genomics in radiation biology: a gateway to cellular systems-level studies Radiat Environ Biophy 47 25 31
3. SA Amundson MB Grace CB McLeland MW Epperly A Yeager Zhan Qimin JS Greenberger AJ Fornace Jr 2004 Human in vivo radiation-induced biomarkers: gene expression changes in radiotherapy patients Cancer Res 64 6368 6371
4. M Boerma CGC van der Wees H Vrieling JP Svensson J Wondergem A van der Laarse LHF Mullenders AA van Zeeland 2005 Microarray analysis of gene expression profiles of cardiac myocytes and fibroblasts after mechanical stress, ionising or ultraviolet radiation BMC Genomics 6 6 15
5. MA Chaudhry LA Chodosh WG McKenna RJ Muschel 2003 Gene expression profile of human cells irradiated in G1 and G2 phases of cell cycle Cancer Lett 195 221 233
6. C Cireli G Tononi 2000 Gene expression in the brain across the sleep-waking cycle Brain Res 885 303 321
7. LH Ding M Shingyoji F Chen JJ Hwang S Burma C Lee JF Cheng DJ Chen 2005 Gene expression profiles of normal human fibroblasts after exposure to ionizing radiation: a comparative study of low and high doses Radiat Res 164 17 26
8. NA Franken R Ten Cate C van Bree J Haveman 2004 Induction of the early response protein EGR-1 in human tumour cells after ionizing radiation is correlated with a reduction of repair of lethal lesions and an increase of repair of sublethal lesions Int J Oncol 24 1027 1031
9. WF Guo RX Lin J Huang Z Zhou J Yang GZ Guo SQ Wang 2005 Identification of differentially expressed genes contributing to radioresistance in lung cancer cells using microarray analysis Radiat Res 164 27 35
10. JY Hsu ZW Sun X Li M Reuben K Tatchell DK Bishop JM Grushcow CJ Brame JA Caldwell DF Hunt F Lin MM Smith CD Allis 2000 Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes Cell 102 279 291
11. K Ishikawa H Ishii T Saito 2006 DNA damage-dependent cell cycle checkpoints and genomic stability DNA and Cell Biol 25 406 411
12. PA Jeggo M Löbrich 2006 Contribution of DNA repair and cell cycle checkpoint arrest to the maintenance of genomic stability DNA repair (Amst) 5 1192 1198
13. KY Jen VG Cheung 2003 Transcriptional response of lymphoblastoid cells to ionizing radiation Genome Res 13 2092 2100
14. E Kis T Szatmári M Keszei R Farkas O Esik K Lumniczky A Falus G Sáfrány 2006 Microarray analysis of radiation response genes in primary human fibroblasts Int J Radiat Oncol Biol Phys 66 1506 1514
15. M Koike T Shiomi A Koike 2005 Identification of skin injury-related genes induced by ionizing radiation in human keratinocytes using cDNA microarray J Radiat Res 46 173 184
16. V Lanza V Pretazzoli G Olivieri G Pascarella A Panconesi A Negri 2005 Transcriptional responses of human umbilical vein endothelial cells to low dose radiation of ionizing radiation J Radiat Res 46 265 276
17. XH Long ZQ Zhao XP He HP Wang QZ Xu J An B Bai JL Sui PK Zhou 2007 Dose-dependent expression changes of early response genes to ionizing radiation in human lymphoblastoid cells Int J Mol Med 19 607 615
18. M Mori MA Benotmanea I Tironea EL Hooghe-Peters C Desaintesa 2005 Transcriptional response to ionizing radiation in lymphocyte subsets CMLS Cell Mol Life Sci 62 1489 1501
19. E Ojima Y Inoue C Miki M Mori M Kusunoki 2007 Effectiveness of gene expression profiling for response prediction of rectal cancer to preoperative radiotherapy J Gastroenterol 42 730 736
20. A Okada K Kushima Y Aoki M Bialer M Fujiwara 2005 Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice Birth Defects Res (Part A): Clinic Mol Teratol 73 229 238
21. JP Svensson LJA Stalpers REE Esveldt-van Lange NAP Franken J Haveman B Klein I Turesson H Vrieling M Giphart-Gassler 2006 Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity PloS Med 3 1904 1914
22. HP Wang XH Long ZZ Sun O Rigaud QZ Xu YC Huang JL Sui B Bai PK Zhou 2006 Identification of differentially transcribed genes in human lymphoblastoid cells irradiated with 0.5 Gy of γ-ray and the involvement of low dose radiation inducible CHD6 gene in cell proliferation and radiosensitivity Int J Radiat Biol 82 181 190
23. M Williams MS Lyu YL Yang EP Lin R Dunbrack B Birren J Cunningham K Hunter 1999 IER5, a novel member of the slow-kinetics immediate-early genes Genomics 55 327 334
24. JA Winkles 1998 Serum- and polypeptide growth factor-inducible gene expression in mouse fibroblast Prog Nucleic Acid Res Mol Biol 58 41 78