Oxygen-glucose deprivation activates 5-lipoxygenase mediated by oxidative stress through the p38 mitogen-activated protein kinase pathway in PC12 cells

Journal of Neuroscience Research

Volumn 87, Issue 4, 2009, Pages 991-1001

  Li, Cheng Tan ^a,b   Zhang, Wei Ping ^a   Lu, Yun Bi ^a   Fang, San Hua ^a   Yuan, Yu Mei ^a   Qi, Ling Ling ^a   Zhang, Li Hui ^b   Huang, Xiao Jia ^a   Zhang, Lei ^a   Chen, Zhong ^a   Wei, Er Qing ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b HANGZHOU NORMAL UNIVERSITY   (China)

Author keywords

5 lipoxygenase; Ischemia reperfusion; PC12 cells; Reactive oxygen species

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ARACHIDONATE 5 LIPOXYGENASE; CAFFEIC ACID; GLUCOSE; GREEN FLUORESCENT PROTEIN; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; NORPHENAZONE; OXYGEN; PEPTIDOLEUKOTRIENE; REACTIVE OXYGEN METABOLITE; ZILEUTON; 5-LIPOXYGENASE-ACTIVATING PROTEIN; ANTIOXIDANT; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; CAFFEIC ACID DERIVATIVE; CARRIER PROTEIN; DRUG DERIVATIVE; ENZYME INHIBITOR; HYDROXYUREA; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; LEUKOTRIENE; MEMBRANE PROTEIN; PHENAZONE; PHENYLMETHYLPYRAZOLONE; PYRIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; CELL STRAIN; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; GENE TRANSLOCATION; GENETIC TRANSFECTION; ISCHEMIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RAT; REPERFUSION INJURY; ANIMAL; CELL HYPOXIA; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; ANTIPYRINE; ARACHIDONATE 5-LIPOXYGENASE; CAFFEIC ACIDS; CARRIER PROTEINS; CELL HYPOXIA; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUCOSE; HYDROGEN PEROXIDE; HYDROXYUREA; IMIDAZOLES; INDOLES; LEUKOTRIENES; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PC12 CELLS; PHOSPHORYLATION; PYRIDINES; RATS; REACTIVE OXYGEN SPECIES; TRANSFECTION;

EID: 63849342063     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21913     Document Type: Article

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