Unique among unique. Is it genetically determined?

British Journal of Sports Medicine

Volumn 43, Issue 4, 2009, Pages 307-309

  Gonzalez Freire, M ^a   Santiago, C ^a   Verde, Z ^a   Lao, J I ^b   Olivan, J ^a   FGomez Gallego ^a   Lucia, A ^a  

^a UNIVERSIDAD EUROPEA DE MADRID   (Spain)

^b Sabiobbi SL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACE GENE; ACTN3 GENE; AMPD1 GENE; ARTICLE; ATHLETE; CKMM GENE; CONTROLLED STUDY; ENDURANCE; ENVIRONMENTAL FACTOR; GDF8 GENE; GENE; GENETIC POLYMORPHISM; GENOTYPE; HFE GENE; HUMAN; MALE; NORMAL HUMAN; PHENOTYPE; PPARGC1A GENE; RUNNING; SPORTING EVENT; TRAINING;

ACTININ; AFRICAN CONTINENTAL ANCESTRY GROUP; AMP DEAMINASE; CREATINE KINASE, MM FORM; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENOTYPE; HEAT-SHOCK PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MALE; MEMBRANE PROTEINS; MYOSTATIN; PEPTIDYL-DIPEPTIDASE A; PHYSICAL ENDURANCE; POLYMORPHISM, GENETIC; RUNNING; TRANSCRIPTION FACTORS;

EID: 63849304925     PISSN: 03063674     EISSN: 14730480     Source Type: Journal    
DOI: 10.1136/bjsm.2008.049809     Document Type: Article

References (13)

1. Lucia A, Oliván J, Bravo J, et al. The key to top-level endurance running performance: a unique example. Br J Sports Med 2008;42:172-4.
2. Yang N, MacArthur DG, Wolde B, et al. The ACTN3 R577X polymorphism in East and West African athletes. Med Sci Sports Exerc 2007;39:1985-8.
3. Jones A, Woods DR. Skelet al muscle RAS and exercise performance. Int J Biochem Cell Biol 2003;35:855-66.
4. Williams AG, Rayson MP, Jubb M, et al. The ACE gene and muscle performance. Nature 2000;403:614.
5. Lucia A, Gómez-Gallego F, Barroso I, et al. PPARGC1A genotype (Gly482Ser) predicts exceptional endurance capacity in European men. J Appl Physiol 2005;99:344-8.
6. Rubio JC, Martín MA, Rabadán M, et al. Frequency of the C34T mutation of the AMPD1 gene in world-class endurance athletes: does this mutation impair performance? J Appl Physiol 2005;98:2108-12.
7. 2max in the HERITAGE Family Study. Med Sci Sports Exerc 1997;29:1311-17.
8. Ferrell RE, Conte V, Lawrence EC, et al. Frequent sequence variation in the human myostatin (GDF8) gene as a marker for analysis of muscle-related phenotypes. Genomics 1999;62:203-7.
9. Huygens W, Thomis MA, Peeters MW, et al. Linkage of myostatin pathway genes with knee strength in humans. Physiol Genomics 2004;17:264-70.
10. Seibert MJ, Xue QL, Fried LP, et al. Polymorphic variation in the human myostatin (GDF-8) gene and association with strength measures in the Women's Health and Aging Study II cohort. J Am Geriatr Soc 2001;49:1093-6.
11. Chicharro JL, Hoyos J, Góimez-Gallego F, et al. Mutations in the hereditary haemochromatosis gene HFE in professional endurance athletes. Br J Sports Med 2004;38:418-21.
12. Chanock SJ, Manolio T, Boehnke M, et al, NCI-NHGRI Working Group on Replication in Association Studies. Replicating genotype-phenotype associations. Nature 2007;447:655-60.
13. Lucia A, Gómez-Gallego F, Chicharro JL, et al. Is there an association between ACE and CKMM polymorphisms and cycling performance status during 3-week races? Int J Sports Med 2005;26:442-7.