The GO system prevents ROS-induced mutagenesis and killing in Pseudomonas aeruginosa

FEMS Microbiology Letters

Volumn 294, Issue 1, 2009, Pages 89-96

  Sanders, Laurie H ^a   Sudhakaran, Julee ^a   Sutton, Mark D ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Base excision repair; DNA damage; Mutations; Pathogenesis; Reactive oxygen species

Indexed keywords

GENE PRODUCT; GUANINE DERIVATIVE; HYDROGEN PEROXIDE; NUCLEOTIDE; REACTIVE OXYGEN METABOLITE; RIFAMPICIN;

AIRWAY; ARTICLE; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; CYSTIC FIBROSIS; CYTOTOXICITY; GENE INACTIVATION; GENE MUTATION; MUTAGENESIS; MUTATION RATE; MUTM GENE; MUTT GENE; MUTY GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RPOB GENE; SEQUENCE ANALYSIS;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DEOXYGUANOSINE; DNA REPAIR; GENE DELETION; HUMANS; HYDROGEN PEROXIDE; MICROBIAL VIABILITY; MUTAGENS; MUTATION; PSEUDOMONAS AERUGINOSA; REACTIVE OXYGEN SPECIES;

PSEUDOMONAS AERUGINOSA;

EID: 63849248363     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2009.01550.x     Document Type: Article

References (28)

1. Asagoshi K, Yamada T, Okada Y, Terato H, Ohyama Y, Seki S Ide H (2000) Recognition of formamidopyrimidine by Escherichia coli and mammalian thymine glycol glycosylases. Distinctive paired base effects and biological and mechanistic implications. J Biol Chem 275 : 24781 24786.
2. Cabrera M, Nghiem Y Miller JH (1988) mutM, a second mutator locus in Escherichia coli that generates G.C-T.A transversions. J Bacteriol 170 : 5405 5407.
3. Ciofu O, Riis B, Pressler T, Poulsen HE Hoiby N (2005) Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammation. Antimicrob Agents Chemoth 49 : 2276 2282.
4. Friedberg EC, Walker GC, Siede W, Wood RD, Schultz RA Ellenberger T (2006) DNA Repair and Mutagenesis. ASM Press, Washington, DC.
5. Garibyan L, Huang T, Kim M et al 2003) Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome. DNA Repair 2 : 593 608.
6. Gomez MI Prince A (2007) Opportunistic infections in lung disease: Pseudomonas infections in cystic fibrosis. Curr Opin Pharmacol 7 : 244 251.
7. Gutierrez O, Juan C, Perez JL Oliver A (2004) Lack of association between hypermutation and antibiotic resistance development in Pseudomonas aeruginosa isolates from intensive care unit patients. Antimicrob Agents Chemoth 48 : 3573 3575.
8. Hall LM Henderson-Begg SK (2006) Hypermutable bacteria isolated from humans - a critical analysis. Microbiology 152 : 2505 2514.
9. Hazra TK, Izumi T, Venkataraman R, Kow YW, Dizdaroglu M Mitra S (2000) Characterization of a novel 8-oxoguanine-DNA glycosylase activity in Escherichia coli and identification of the enzyme as endonuclease VIII. J Biol Chem 275 : 27762 27767.
10. Jacobs MA, Alwood A, Thaipisuttikul I et al 2003) Comprehensive transposon mutant library of Pseudomonas aeruginosa. P Natl Acad Sci USA 100 : 14339 14344.
11. Jin DJ Gross CA (1988) Mapping and sequence of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance. J Mol Biol 202 : 45 58.
12. Konstan MW, Hilliard KA, Norvell TM Berger M (1994) Bronchoalveolar lavage findings in cystic inflammation. Am J Resp Crit Care 150 : 448 454.
13. Macia MD, Blanquer D, Togores B, Sauleda J, Perez JL Oliver A (2005) Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infections. Antimicrob Agents Chemoth 49 : 3382 3386.
14. Maga G, Villani G, Crespan E, Wimmer U, Ferrari E, Bertocci B Hubscher U (2007) 8-Oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins. Nature 447 : 606 608.
15. Maki H Sekiguchi M (1992) MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis. Nature 355 : 273 275.
16. McKenzie GJ Rosenberg SM (2001) Adaptive mutations, mutator DNA polymerases and genetic change strategies of pathogens. Curr Opin Microbiol 4 : 586 594.
17. Metzgar D Wills C (2000) Evidence for the adaptive evolution of mutation rates. Cell 101 : 581 584.
18. Michaels ML Miller JH (1992) The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8- oxoguanine). J Bacteriol 174 : 6321 6325.
19. Morero NR Argarana CE (2009) Pseudomonas aeruginosa deficient in 8-oxodeoxyguanine repair system shows a high frequency of resistance to ciprofloxacin. FEMS Microbiol Lett 290 : 217 226.
20. Nghiem Y, Cabrera M, Cupples CG Miller JH (1988) The mutY gene: a mutator locus in Escherichia coli that generates G.C-T.A transversions. P Natl Acad Sci USA 85 : 2709 2713.
21. Oliver A, Canton R, Campo P, Baquero F Blazquez J (2000) High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. Science 288 : 1251 1254.
22. Oliver A, Sanchez JM Blazquez J (2002) Characterization of the GO system of Pseudomonas aeruginosa. FEMS Microbiol Lett 217 : 31 35.
23. Sanders LH, Rockel A, Lu H, Wozniak DJ Sutton MD (2006) Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis. J Bacteriol 188 : 8573 8585.
24. Saumaa S, Tover A, Tark M, Tegova R Kivisaar M (2007) Oxidative DNA damage defense systems in avoidance of stationary-phase mutagenesis in Pseudomonas putida. J Bacteriol 189 : 5504 5514.
25. Shibutani S, Takeshita M Grollman AP (1991) Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 349 : 431 434.
26. Wyrzykowski J Volkert MR (2003) The Escherichia coli methyl-directed mismatch repair system repairs base pairs containing oxidative lesions. J Bacteriol 185 : 1701 1704.
27. Yamada M, Nunoshiba T, Shimizu M, Gruz P, Kamiya H, Harashima H Nohmi T (2006) Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli. J Bacteriol 188 : 4992 4995.
28. Yanofsky C, Cox EC Horn V (1966) The unusual mutagenic specificity of an E. coli mutator gene. P Natl Acad Sci USA 55 : 274 281.