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Volumn 14, Issue 2, 2009, Pages 453-462

Epigenetic regulation of cystatins in cancer

Author keywords

Cancer; Cystatins; Cysteine protease inhibitor; DNA methylation; Epigenetic; Review

Indexed keywords

CYSTATIN;

EID: 63849236804     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3254     Document Type: Review
Times cited : (28)

References (92)
  • 1
    • 0345357773 scopus 로고    scopus 로고
    • Gene Silencing in Cancer in Association with Promoter Hypermethylation
    • DOI 10.1056/NEJMra023075
    • Herman, J. G. and S. B. Baylin: Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349, 2042-54(2003) (Pubitemid 37448928)
    • (2003) New England Journal of Medicine , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 2
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • DOI 10.1126/science.1063852
    • Jones, P. A. and D. Takai: The role of DNA methylation in mammalian epigenetics. Science 293, 1068-70(2001) (Pubitemid 32758075)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 4
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird, A. P.: CpG-rich islands and the function of DNA methylation. Nature 321, 209-13(1986) (Pubitemid 16016411)
    • (1986) Nature , vol.321 , Issue.6067 , pp. 209-213
    • Bird, A.P.1
  • 5
    • 0019318994 scopus 로고
    • DNA methylation and gene function
    • Razin, A. and A. D. Riggs: DNA methylation and gene function. Science 210, 604-10(1980)
    • (1980) Science , vol.210 , pp. 604-610
    • Razin, A.1    Riggs, A.D.2
  • 7
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones, P. A. and S. B. Baylin: The fundamental role of epigenetic events in cancer. Nat Rev Genet 3, 415-28(2002) (Pubitemid 34587077)
    • (2002) Nature Reviews Genetics , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 8
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • DOI 10.1038/5947
    • Jones, P. A. and P. W. Laird: Cancer epigenetics comes of age. Nat Genet 21, 163-7(1999) (Pubitemid 29070360)
    • (1999) Nature Genetics , vol.21 , Issue.2 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 9
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. and R. A. Weinberg: The hallmarks of cancer. Cell 100, 57-70(2000) (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 10
    • 33847628167 scopus 로고    scopus 로고
    • DNA methylation-dependent epigenetic regulation of gene expression in MCF-7 breast cancer cells
    • Rivenbark, A. G., W. D. Jones, J. D. Risher and W. B. Coleman: DNA methylation-dependent epigenetic regulation of gene expression in MCF-7 breast cancer cells. Epigenetics 1, 32-44(2006)
    • (2006) Epigenetics , vol.1 , pp. 32-44
    • Rivenbark, A.G.1    Jones, W.D.2    Risher, J.D.3    Coleman, W.B.4
  • 11
    • 33751205602 scopus 로고    scopus 로고
    • DNA methylation-dependent silencing of CST6 in human breast cancer cell lines
    • DOI 10.1038/labinvest.3700485, PII 3700485
    • Rivenbark, A. G., W. D. Jones and W. B. Coleman: DNA methylation- dependent silencing of CST6 in human breast cancer cell lines. Lab Invest 86, 1233-1242(2006) (Pubitemid 44789913)
    • (2006) Laboratory Investigation , vol.86 , Issue.12 , pp. 1233-1242
    • Rivenbark, A.G.1    Jones, W.D.2    Coleman, W.B.3
  • 12
    • 33748041100 scopus 로고    scopus 로고
    • Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression
    • DOI 10.1158/0008-5472.CAN-06-0576
    • Ai, W. J. Kim, T. Y. Kim, C. R. Fields, N. A. Massoll, K. D. Robertson and K. D. Brown: Epigenetic Silencing of the Tumor Suppressor Cystatin M Occurs during Breast Cancer Progression. Cancer Res 66, 7899-7909(2006) (Pubitemid 44299152)
    • (2006) Cancer Research , vol.66 , Issue.16 , pp. 7899-7909
    • Ai, L.1    Kim, W.-J.2    Kim, T.-Y.3    Fields, C.R.4    Massoll, N.A.5    Robertson, K.D.6    Brown, K.D.7
  • 14
    • 33747889966 scopus 로고    scopus 로고
    • Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma
    • DOI 10.1158/0008-5472.CAN-05-4552
    • Kim, T. Y., S. Zhong, C. R. Fields, J. H. Kim and K. D. Robertson: Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res 66, 7490-501(2006) (Pubitemid 44289203)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7490-7501
    • Kim, T.-Y.1    Zhong, S.2    Fields, C.R.3    Kim, J.H.4    Robertson, K.D.5
  • 15
    • 36749095998 scopus 로고    scopus 로고
    • Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer
    • Zhong, S., C. R. Fields, N. Su, Y. X. Pan and K. D. Robertson: Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer. Oncogene, Epub (2006)
    • (2006) Oncogene, Epub
    • Zhong, S.1    Fields, C.R.2    Su, N.3    Pan, Y.X.4    Robertson, K.D.5
  • 16
    • 33646037877 scopus 로고
    • Biochemical study of cellular antigen-antibody reaction in tissue culture. I. Activation and release of a protease
    • Hayashi, H., A. Tokuda and K. Udaka: Biochemical study of cellular antigen-antibody reaction in tissue culture. I. Activation and release of a protease. J. Exp. Med. 112, 237-247(1960)
    • (1960) J. Exp. Med , vol.112 , pp. 237-247
    • Hayashi, H.1    Tokuda, A.2    Udaka, K.3
  • 17
    • 33646067439 scopus 로고    scopus 로고
    • Towards novel anti-cancer strategies based on cystatin function
    • Keppler, D.: Towards novel anti-cancer strategies based on cystatin function. Cancer Lett 235, 159-76(2006)
    • (2006) Cancer Lett , vol.235 , pp. 159-176
    • Keppler, D.1
  • 18
    • 17044379501 scopus 로고    scopus 로고
    • Proteinaceous cysteine protease inhibitors
    • Dubin, G.: Proteinaceous cysteine protease inhibitors. Cell. Mol. Life Sci. 62, 653-669(2005)
    • (2005) Cell. Mol. Life Sci , vol.62 , pp. 653-669
    • Dubin, G.1
  • 19
    • 0019722502 scopus 로고
    • Rat liver thiol proteinases: Cathepsin B, cathepsin H and cathepsin L
    • Katunuma, N., T. Towatari, E. Kominami, S. Hashida, K. Takio and K. Titani: Rat liver thiol porteinases: cathepsin B, cathepsin H, and catepsin L. Acta Biol. Med. Ger. 40, 1419-1425(1981) (Pubitemid 12022355)
    • (1981) Acta Biologica et Medica Germanica , vol.40 , Issue.10-11 , pp. 1419-1425
    • Katunuma, N.1    Towatari, T.2    Kominami, E.3
  • 20
    • 0020770394 scopus 로고
    • Homology of amino acid sequences of rat liver cathepsins B and H with that of papain
    • Takio, K., T. Towatari, N. Katunuma, D. Teller and K. Titani: Homology of amino acid sequences of rat liver cathepsins B and H with that of papain. Proc. Natl Acad. Sci. USA 80, 3666-3670(1983)
    • (1983) Proc. Natl Acad. Sci. USA , vol.80 , pp. 3666-3670
    • Takio, K.1    Towatari, T.2    Katunuma, N.3    Teller, D.4    Titani, K.5
  • 22
    • 0031685364 scopus 로고    scopus 로고
    • Cysteine proteinases and their endogenous inhibitors: Target proteins for prognosis, diagnosis and therapy in cancer (review)
    • Kos, J. and T. Lah: Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis, and therapy in cancer (Review). Oncol Rep 5, 1349-1361(1998) (Pubitemid 28474074)
    • (1998) Oncology Reports , vol.5 , Issue.6 , pp. 1349-1361
    • Kos, J.1    Lah, T.T.2
  • 23
    • 33750984761 scopus 로고    scopus 로고
    • The role of cystatins in cells of the immune system
    • DOI 10.1016/j.febslet.2006.10.055, PII S0014579306012841
    • Kopitar-Jerala, N.: The role of cystatins in cells of the immune system. FEBS Letters 580, 6295-6301(2006) (Pubitemid 44750929)
    • (2006) FEBS Letters , vol.580 , Issue.27 , pp. 6295-6301
    • Kopitar-Jerala, N.1
  • 25
    • 1642464622 scopus 로고    scopus 로고
    • Evolutionary families of peptidase inhibitors
    • DOI 10.1042/BJ20031825
    • Rawlings, N., D. Tolle and A. Barrett: Evolutionary families of peptidase inhibitors. Biochem J. 378, 705-716(2004) (Pubitemid 38406845)
    • (2004) Biochemical Journal , vol.378 , Issue.3 , pp. 705-716
    • Rawlings, N.D.1    Tolle, D.P.2    Barrett, A.J.3
  • 26
    • 0024066065 scopus 로고
    • The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases
    • Bode, W., R. Engh, D. Musil, U. Thiele, R. Huber, A. Karshikov, J. Brzin, J. Kos and V. Turk: The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. Eur. Mol. Biol. Org. J. 7, 2593-2599(1988)
    • (1988) Eur. Mol. Biol. Org. J , vol.7 , pp. 2593-2599
    • Bode, W.1    Engh, R.2    Musil, D.3    Thiele, U.4    Huber, R.5    Karshikov, A.6    Brzin, J.7    Kos, J.8    Turk, V.9
  • 27
    • 0025817602 scopus 로고
    • The cystatins: Protein inhibitors of cysteine proteinases
    • Turk, V. and W. Bode: The cystatins: protein inhibitors of cysteine proteinases. FEBS Letters 285, 213-219(1991)
    • (1991) FEBS Letters , vol.285 , pp. 213-219
    • Turk, V.1    Bode, W.2
  • 30
    • 0037096882 scopus 로고    scopus 로고
    • Prediction of pelvic lymph node metastasis by the ratio of cathepsin B to stefin A in patients with prostate carcinoma
    • DOI 10.1002/cncr.10604
    • Sinha, A., B. Quast, M. Wilson, E. Fernandes, P. Reddy, S. Ewing and D. Gleason: Prediction of pelvic lymph node metastasis by the ratio of cathepsin B to stefin A in patients with prostate carcinoma. Cancer 94, 3141-3149(2002) (Pubitemid 34670497)
    • (2002) Cancer , vol.94 , Issue.12 , pp. 3141-3149
    • Sinha, A.A.1    Quast, B.J.2    Wilson, M.J.3    Fernandes, E.T.4    Reddy, P.K.5    Ewing, S.L.6    Gleason, D.F.7
  • 32
    • 34248159369 scopus 로고    scopus 로고
    • Lymph node status as a guide to selection of available prognostic markers in breast cancer: The clinical practice of the future?
    • Elzagheid, A., T. Kuopio, S. Pyrhonen and Y. Collan: Lymph node status as a guide to selection of available prognostic markers in breast cancer: the clinical practice of the future? Diagnostic Path. 1, 41(2006)
    • (2006) Diagnostic Path , vol.1 , pp. 41
    • Elzagheid, A.1    Kuopio, T.2    Pyrhonen, S.3    Collan, Y.4
  • 33
    • 0034059284 scopus 로고    scopus 로고
    • Prognostic significance of cysteine proteinases cathepsins B and L and their endogenous inhibitors stefins A and B in patients with squamous cell carcinoma of the head and neck
    • Strojan, P., M. Budihna, L. Smid, B. Svetic, I. Vrhovec, J. Kos and J. Skrk: Prognostic significance of cysteine proteinases cathepsins B and L and their endogenous inhibitors stefins A and B in patients with squamous cell carcinoma of the head and neck. Clin. Cancer Res. 6, 1052-1062(2000) (Pubitemid 30159367)
    • (2000) Clinical Cancer Research , vol.6 , Issue.3 , pp. 1052-1062
    • Strojan, P.1    Budihna, M.2    Smid, L.3    Svetic, B.4    Vrhovec, I.5    Kos, J.6    Skrk, J.7
  • 35
    • 0026552859 scopus 로고
    • Cell interactions and motility in human lung tumor cell lines HS-24 and SB-3 under the influence of extracellular matrix components and proteinase inhibitors
    • Erdel, M., E. Spiess, G. Trefz, H. Boxberger and W. Ebert: Cell interactions and motility in human lung tumor cell lines HS-24 and SB-3 under the influence of extracellular matrix components and proteinase inhibitors. Anticancer Res. 12, 349-359(1992)
    • (1992) Anticancer Res , vol.12 , pp. 349-359
    • Erdel, M.1    Spiess, E.2    Trefz, G.3    Boxberger, H.4    Ebert, W.5
  • 36
    • 0026621802 scopus 로고
    • A possible role for cysteine proteinase and its inhibitors in motility of malignant melanoma and other tumour cells
    • Boike, G., T. Lah, B. Sloane, J. Rozhin, K. Honn, R. Guirquis, M. Stracke, L. Liotta and E. Schiffmann: A possible role for cysteine proteinase and its inhibitors in motility of malignant melanoma and other tumour cells. Melanoma Res. 1, 333-340(1992)
    • (1992) Melanoma Res , vol.1 , pp. 333-340
    • Boike, G.1    Lah, T.2    Sloane, B.3    Rozhin, J.4    Honn, K.5    Guirquis, R.6    Stracke, M.7    Liotta, L.8    Schiffmann, E.9
  • 37
    • 0031665920 scopus 로고    scopus 로고
    • Mapping of a new target region of allelic loss to a 6-cM interval at 21q21 in primary breast cancers
    • DOI 10.1002/(SICI)1098-2264(19981 1)23:3<244::AID-GCC6>3.0.CO;2-1
    • Ohgaki, K., A. Iida, F. Kasumi, G. Sakamoto, M. Akimoto, Y. Nakamura and M. Emi: Mapping of a new target region of allelic loss to a 6-cM interval at 21q21 in primary breast cancers. Genes Chromosomes Cancer 23, 244-7(1998) (Pubitemid 28465641)
    • (1998) Genes Chromosomes and Cancer , vol.23 , Issue.3 , pp. 244-247
    • Ohgaki, K.1    Iida, A.2    Kasumi, F.3    Sakamoto, G.4    Akimoto, M.5    Nakamura, Y.6    Emi, M.7
  • 38
    • 0037068360 scopus 로고    scopus 로고
    • DNA methylation and breast carcinogenesis
    • DOI 10.1038/sj.onc.1205606
    • Widschwendter, M. and P. A. Jones: DNA methylation and breast carcinogenesis. Oncogene 21, 5462-82(2002) (Pubitemid 34983482)
    • (2002) Oncogene , vol.21 , Issue.35 REV. ISSUE 3 , pp. 5462-5482
    • Widschwendter, M.1    Jones, P.A.2
  • 39
    • 0037742210 scopus 로고    scopus 로고
    • Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays
    • Sato, N., N. Fukushima, A. Maitra, H. Matsubayashi, C. J. Yeo, J. L. Cameron, R. H. Hruban and M. Goggins: Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays. Cancer Res 63, 3735-42(2003) (Pubitemid 36793060)
    • (2003) Cancer Research , vol.63 , Issue.13 , pp. 3735-3742
    • Sato, N.1    Fukushima, N.2    Maitra, A.3    Matsubayashi, H.4    Yeo, C.J.5    Cameron, J.L.6    Hruban, R.H.7    Goggins, M.8
  • 41
    • 0036171225 scopus 로고    scopus 로고
    • Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine
    • Liang, G., F. A. Gonzales, P. A. Jones, T. F. Orntoft and T. Thykjaer: Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine. Cancer Res 62, 961-6(2002) (Pubitemid 34160269)
    • (2002) Cancer Research , vol.62 , Issue.4 , pp. 961-966
    • Liang, G.1    Gonzales, F.A.2    Jones, P.A.3    Orntoft, T.F.4    Thykjaer, T.5
  • 42
    • 0034723255 scopus 로고    scopus 로고
    • Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression
    • DOI 10.1074/jbc.275.4.2727
    • Graff, J. R., E. Gabrielson, H. Fujii, S. B. Baylin and J. G. Herman: Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression. J Biol Chem 275, 2727-32(2000) (Pubitemid 30082043)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.4 , pp. 2727-2732
    • Graff, J.R.1    Gabrielson, E.2    Fujii, H.3    Baylin, S.B.4    Herman, J.G.5
  • 43
    • 0034680012 scopus 로고    scopus 로고
    • Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells
    • Arapshian A., Y. S. Kuppumbatti and R. Mira-y-Lopez: Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells. Oncogene 19, 4066-70(2000)
    • (2000) Oncogene , vol.19 , pp. 4066-4070
    • Arapshian, A.1    Kuppumbatti, Y.S.2    Mira-y-Lopez, R.3
  • 44
    • 16544389958 scopus 로고    scopus 로고
    • Promoter Methylation Inhibits APC Gene Expression by Causing Changes in Chromatin Conformation and Interfering with the Binding of Transcription Factor CCAAT-Binding Factor
    • DOI 10.1158/0008-5472.CAN-03-3000
    • Deng G., G. A. Song, E. Pong, M. Sleisenger and Y. S. Kim: Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor. Cancer Res 64, 2692-8(2004) (Pubitemid 38500603)
    • (2004) Cancer Research , vol.64 , Issue.8 , pp. 2692-2698
    • Deng, G.1    Song, G.-A.2    Pong, E.3    Sleisenger, M.4    Kim, Y.S.5
  • 50
    • 0041813308 scopus 로고    scopus 로고
    • Molecular background of progressive myoclonus epilepsy
    • Lehesjoki, A. E.: Molecular background of progressive myoclonus epilepsy. Embo J 22, 3473-8(2003)
    • (2003) Embo J , vol.22 , pp. 3473-3478
    • Lehesjoki, A.E.1
  • 51
    • 0029882077 scopus 로고    scopus 로고
    • Gene perplexes epilepsy researchers
    • DOI 10.1126/science.271.5256.1672
    • O'Brien, C.: Gene perplexes epilepsy researchers. Science 271, 1672(1996) (Pubitemid 26102814)
    • (1996) Science , vol.271 , Issue.5256 , pp. 1672
    • O'Brien, C.1
  • 53
    • 0037058622 scopus 로고    scopus 로고
    • Expression of cysteine peptidase cathepsin L and its inhibitors stefins A and B in relation to tumorigenicity of breast cancer cell lines
    • DOI 10.1016/S0304-3835(02)00452-4, PII S0304383502004524
    • Zajc I., N. Sever, A. Bervar and T. Lah: Expression of cysteine peptidase cathepsin L and its inhibitors stefins A and B in relation to tumorigenicity of breast cancer cell lines. Cancer Letters 187, 185-190(2002) (Pubitemid 35279348)
    • (2002) Cancer Letters , vol.187 , Issue.1-2 , pp. 185-190
    • Zajc, I.1    Sever, N.2    Bervar, A.3    Lah, T.T.4
  • 54
    • 0011194281 scopus 로고    scopus 로고
    • The expression of lysosomal proteinases and their inhibitors in breast cancer: Possible realtionship to prognosis of the disease
    • Lah T., J. Kos, A. Blejec, S. Frkovic-Grazio, R. Golouh, I. Vrhovec and V. Turk: The expression of lysosomal proteinases and their inhibitors in breast cancer: possible realtionship to prognosis of the disease. Pathology Oncology Res. 3, 221-233(1997)
    • (1997) Pathology Oncology Res , vol.3 , pp. 221-233
    • Lah, T.1    Kos, J.2    Blejec, A.3    Frkovic-Grazio, S.4    Golouh, R.5    Vrhovec, I.6    Turk, V.7
  • 55
    • 0036947460 scopus 로고    scopus 로고
    • Comparison of cysteine proteinases cathepsin B, cathepsin L and serine proteinase urokinase (u-PA) and their endogenous inhibitors with clinico-pathological data of breast carcinoma patients
    • Levicar N., J. Kos, A. Blejec, R. Golouh, I. Vrhovec, S. Frkovic-Grazio and T. Lah: Comparison of cysteine proteinases cathepsin B, cathepsin L and serine proteinase urokinase (u-PA) and their endogenous inhibitors with clinico-pathological data of breast carcinoma patients. Cancer Detect. Prev. 26, 42-49(2002)
    • (2002) Cancer Detect. Prev , vol.26 , pp. 42-49
    • Levicar, N.1    Kos, J.2    Blejec, A.3    Golouh, R.4    Vrhovec, I.5    Frkovic-Grazio, S.6    Lah, T.7
  • 56
    • 0242539836 scopus 로고    scopus 로고
    • Cancer epigenetics
    • Momparler, R. L.: Cancer epigenetics. Oncogene 22, 6479-83(2003) (Pubitemid 37372327)
    • (2003) Oncogene , vol.22 , Issue.43 , pp. 6479-6483
    • Momparler, R.L.1
  • 57
    • 0025981310 scopus 로고
    • Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region
    • Prendergast, G. C. and E. B. Ziff: Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science 251, 186-9(1991) (Pubitemid 21916865)
    • (1991) Science , vol.251 , Issue.4990 , pp. 186-189
    • Prendergast, G.C.1    Ziff, E.B.2
  • 58
    • 0024342686 scopus 로고
    • Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs
    • DOI 10.1016/0092-8674(89)90430-3
    • Meehan, R. R., J. D. Lewis, S. McKay, E. L. Kleiner and A. P. Bird: Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs. Cell 58, 499-507(1989) (Pubitemid 19203534)
    • (1989) Cell , vol.58 , Issue.3 , pp. 499-507
    • Meehan, R.R.1    Lewis, J.D.2    McKay, S.3    Kleiner, E.L.4    Bird, A.P.5
  • 59
    • 23844490237 scopus 로고    scopus 로고
    • In vivo and in vitro analysis of the human tissue-type plasminogen activator gene promoter in neuroblastomal cell lines: Evidence for a functional upstream κB element
    • DOI 10.1111/j.1538-7836.2005.01276.x
    • Lux W., H. G. Klobeck, P. B. Daniel, M. Costa, R. L. Medcalf and W. D. Schleuning: In vivo and in vitro analysis of the human tissue-type plasminogen activator gene promoter in neuroblastomal cell lines: evidence for a functional upstream kappaB element. J Thromb Haemost 3, 1009-17(2005) (Pubitemid 41632833)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.5 , pp. 1009-1017
    • Lux, W.1    Klobeck, H.-G.2    Daniel, P.B.3    Costa, M.4    Medcalf, R.L.5    Schleuning, W.-D.6
  • 60
  • 61
    • 0028356053 scopus 로고
    • Latency of cathepsin B secreted by human colon carcinoma cells is not linked to secretion of cystatin C and is relieved by neutrophil elastase
    • DOI 10.1016/0925-4439(94)90018-3
    • Keppler D., P. Waridel, M. Abrahamson, D. Bachmann, J. Berdoz and B. Sordat: Latency of cathepsin B secreted by human colon carcinoma cells is not linked to secretion of cystatin C and is relieved by neutrophil elastase. Biochim Biophys Acta 1226, 117-25(1994) (Pubitemid 24182454)
    • (1994) Biochimica et Biophysica Acta - Molecular Basis of Disease , vol.1226 , Issue.2 , pp. 117-125
    • Keppler, D.1    Waridel, P.2    Abrahamson, M.3    Bachmann, D.4    Berdoz, J.5    Sordat, B.6
  • 62
    • 0025022426 scopus 로고
    • Evolution of proteins of the cystatin superfamily
    • Rawlings, N. D. and A. J. Barrett: Evolution of proteins of the cystatin superfamily. J Mol Evol 30, 60-71(1990) (Pubitemid 20050148)
    • (1990) Journal of Molecular Evolution , vol.30 , Issue.1 , pp. 60-71
    • Rawlings, N.D.1    Barrett, A.J.2
  • 63
    • 0035986219 scopus 로고    scopus 로고
    • Regulating cysteine protease activity: Essential role of protease inhibitors as guardians and regulators
    • DOI 10.2174/1381612023394124
    • Turk B., D. Turk and G. S. Salvesen: Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators. Curr Pharm Des 8, 1623-37(2002) (Pubitemid 34752830)
    • (2002) Current Pharmaceutical Design , vol.8 , Issue.18 , pp. 1623-1637
    • Turk, B.1    Turk, D.2    Salvesen, G.S.3
  • 65
    • 12944289667 scopus 로고    scopus 로고
    • Plasma concentrations of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events: More than simply a marker of glomerular filtration rate
    • DOI 10.1373/clinchem.2004.041889
    • Koenig W., D. Twardella, H. Brenner and D. Rothenbacher: Plasma concentrations of cystatin C in patients with coronary heart disease and risk for secondary cardiovascular events: more than simply a marker of glomerular filtration rate. Clin Chem 51, 321-7(2005) (Pubitemid 40175801)
    • (2005) Clinical Chemistry , vol.51 , Issue.2 , pp. 321-327
    • Koenig, W.1    Twardella, D.2    Brenner, H.3    Rothenbacher, D.4
  • 66
    • 0027053955 scopus 로고
    • Cystatin C in the human pancreas and gut: An immunohistochemical study of normal and neoplastic tissues
    • Lignelid, H. and B. Jacobsson: Cystatin C in the human pancreas and gut: an immunohistochemical study of normal and neoplastic tissues. Virchows Arch A Pathol Anat Histopathol 421, 491-5(1992) (Pubitemid 23008254)
    • (1992) Virchows Archiv - A Pathological Anatomy and Histopathology , vol.421 , Issue.6 , pp. 491-495
    • Lignelid, H.1    Jacobsson, B.2
  • 67
    • 0030952992 scopus 로고    scopus 로고
    • Cystatin C and transthyretin expression in normal and neoplastic tissues of the human brain and pituitary
    • DOI 10.1007/s004010050644
    • Lignelid H., V. P. Collins and B. Jacobsson: Cystatin C and transthyretin expression in normal and neoplastic tissues of the human brain and pituitary. Acta Neuropathol (Berl) 93, 494-500(1997) (Pubitemid 27186990)
    • (1997) Acta Neuropathologica , vol.93 , Issue.5 , pp. 494-500
    • Lignelid, H.1    Collins, V.P.2    Jacobsson, B.3
  • 68
    • 0029041438 scopus 로고
    • Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells and the proteins are not useful as markers for renal cell carcinomas
    • Jacobsson B., H. Lignelid and U. S. Bergerheim: Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells and the proteins are not useful as markers for renal cell carcinomas. Histopathology 26, 559-64(1995)
    • (1995) Histopathology , vol.26 , pp. 559-564
    • Jacobsson, B.1    Lignelid, H.2    Bergerheim, U.S.3
  • 69
    • 0033041509 scopus 로고    scopus 로고
    • Expression of cathepsin B and cystatin C in human colorectal cancer
    • DOI 10.1016/S0046-8177(99)90094-1
    • Hirai K., M. Yokoyama, G. Asano and S. Tanaka: Expression of cathepsin B and cystatin C in human colorectal cancer. Hum Pathol 30, 680-6(1999) (Pubitemid 29266728)
    • (1999) Human Pathology , vol.30 , Issue.6 , pp. 680-686
    • Hirai, K.1    Yokoyama, M.2    Asano, G.3    Tanaka, S.4
  • 70
    • 13544276456 scopus 로고    scopus 로고
    • Expression analysis of cystatin C and M in laser-capture microdissectioned human breast cancer cells - A preliminary study
    • DOI 10.1016/j.prp.2004.09.005, PII S0344033804001724
    • Vigneswaran, N., J. Wu, S. Muller, W. Zacharias, S. Narendran and L. Middleton: Expression analysis of cystatin C and M in laser-capture microdissectioned human breast cancer cells - a preliminary study. Pathol Res Pract 200, 753-62(2005) (Pubitemid 40220956)
    • (2005) Pathology Research and Practice , vol.200 , Issue.11-12 , pp. 753-762
    • Vigneswaran, N.1    Wu, J.2    Muller, S.3    Zacharias, W.4    Narendran, S.5    Middleton, L.6
  • 71
    • 0342470995 scopus 로고    scopus 로고
    • Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: Relation to prognosis
    • Kos J., M. Krasovec, N. Cimerman, H. J. Nielsen, I. J. Christensen and N. Brunner: Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: relation to prognosis. Clin Cancer Res 6, 505-11(2000) (Pubitemid 30111471)
    • (2000) Clinical Cancer Research , vol.6 , Issue.2 , pp. 505-511
    • Kos, J.1    Krasovec, M.2    Cimerman, N.3    Nielsen, H.J.4    Christensen, I.J.5    Brunner, N.6
  • 73
    • 0034935190 scopus 로고    scopus 로고
    • Cathepsin B/cystatin C complex levels in sera from patients with lung and colorectal cancer
    • DOI 10.1515/BC.2001.097
    • Zore I., M. Krasovec, N. Cimerman, R. Kuhelj, B. Werle, H. J. Nielsen, N. Brunner and J. Kos: Cathepsin B/cystatin C complex levels in sera from patients with lung and colorectal cancer. Biol Chem 382, 805-10(2001) (Pubitemid 32631718)
    • (2001) Biological Chemistry , vol.382 , Issue.5 , pp. 805-810
    • Zore, I.1    Krasovec, M.2    Cimerman, N.3    Kuhelj, R.4    Werle, B.5    Nielsen, H.J.6    Brunner, N.7    Kos, J.8
  • 74
    • 0036191573 scopus 로고    scopus 로고
    • Cystatin C of pleural effusion as a novel diagnostic aid in pleural diseases of different aetiologies
    • DOI 10.1042/CS20010168
    • Domej W., G. P. Tilz, Z. Foldes-Papp, U. Demel, T. Rabold and H. Holzer: Cystatin C of pleural effusion as a novel diagnostic aid in pleural diseases of different aetiologies. Clin Sci (Lond) 102, 373-80(2002) (Pubitemid 34214401)
    • (2002) Clinical Science , vol.102 , Issue.3 , pp. 373-380
    • Domej, W.1    Tilz, G.P.2    Foldes-Papp, Z.3    Demel, U.4    Rabold, T.5    Holzer, H.6
  • 75
    • 0037300636 scopus 로고    scopus 로고
    • Cystatins C, E/M and F in human pleural fluids of patients with neoplastic and inflammatory lung disorders
    • DOI 10.1515/BC.2003.031
    • Werle B., K. Sauckel, C. M. Nathanson, M. Bjarnadottir, E. Spiess, W. Ebert and M. Abrahamson: Cystatins C, E/M and F in human pleural fluids of patients with neoplastic and inflammatory lung disorders. Biol Chem 384, 281-7(2003) (Pubitemid 36348328)
    • (2003) Biological Chemistry , vol.384 , Issue.2 , pp. 281-287
    • Werle, B.1    Sauckel, K.2    Nathanson, C.-M.3    Bjarnadottir, M.4    Spiess, E.5    Ebert, W.6    Abrahamson, M.7
  • 76
    • 0034128337 scopus 로고    scopus 로고
    • Cysteine proteinases and their inhibitors in extracellular fluids: Markers for diagnosis and prognosis in cancer
    • Kos J., B. Werle, T. Lah and N. Brunner: Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer. Int J Biol Markers 15, 84-9(2000) (Pubitemid 30195490)
    • (2000) International Journal of Biological Markers , vol.15 , Issue.1 , pp. 84-89
    • Kos, J.1    Werle, B.2    Lah, T.3    Brunner, N.4
  • 77
    • 0026779586 scopus 로고
    • Cystatin C and cathepsin B in human colon carcinoma: Expression by cell lines and matrix degradation
    • Corticchiato O., J. F. Cajot, M. Abrahamson, S. J. Chan, D. Keppler and B. Sordat: Cystatin C and cathepsin B in human colon carcinoma: expression by cell lines and matrix degradation. Int J Cancer 52, 645-52(1992)
    • (1992) Int J Cancer , vol.52 , pp. 645-652
    • Corticchiato, O.1    Cajot, J.F.2    Abrahamson, M.3    Chan, S.J.4    Keppler, D.5    Sordat, B.6
  • 80
    • 3543106256 scopus 로고    scopus 로고
    • Cystatin C antagonizes transforming growth factor β signaling in normal and cancer cells
    • Sokol, J. P. and W. P. Schiemann: Cystatin C antagonizes transforming growth factor beta signaling in normal and cancer cells. Mol Cancer Res 2, 183-95(2004) (Pubitemid 39030308)
    • (2004) Molecular Cancer Research , vol.2 , Issue.3 , pp. 183-195
    • Sokol, J.P.1    Schiemann, W.P.2
  • 82
    • 0031030180 scopus 로고    scopus 로고
    • Identification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancer
    • DOI 10.1074/jbc.272.2.903
    • Sotiropoulou G., A. Anisowicz and R. Sager: Identification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancer. J Biol Chem 272, 903-10(1997) (Pubitemid 27034580)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.2 , pp. 903-910
    • Sotiropoulou, G.1    Anisowicz, A.2    Sager, R.3
  • 84
    • 30544439044 scopus 로고    scopus 로고
    • Silencing of cystatin M in metastatic oral cancer cell line MDA-686Ln by siRNA increases cysteine proteinases and legumain activities, cell proliferation and in vitro invasion
    • DOI 10.1016/j.lfs.2005.05.096, PII S0024320505007939
    • Vigneswaran N., J. Wu, N. Nagaraj, R. James, P. Zeeuwen and W. Zacharias: Silencing of cystatin M in metastatic oral cancer cell line MDA-686Ln by siRNA increase cysteine proteinases and legumain activities, cell proliferation and in vitro invasion. Life Sciences 78, 898-907(2006) (Pubitemid 43082316)
    • (2006) Life Sciences , vol.78 , Issue.8 , pp. 898-907
    • Vigneswaran, N.1    Wu, J.2    Nagaraj, N.3    James, R.4    Zeeuwen, P.5    Zacharias, W.6
  • 85
    • 0031932089 scopus 로고    scopus 로고
    • Cysteine proteinases in cancer progression and their clinical relevance for prognosis
    • Lah, T. and J. Kos: Cysteine proteinases in cancer progression and their clinical relevance for prognosis. Biol Chem 379, 125-130(1998) (Pubitemid 28075971)
    • (1998) Biological Chemistry , vol.379 , Issue.2 , pp. 125-130
    • Lah, T.T.1    Kos, J.2
  • 86
    • 0003126050 scopus 로고    scopus 로고
    • Molecular regulation, membrane association and secretion of tumor cathepsin B
    • Frosch B., I. Berquin, M. Emmert-Buck, K. Moin and B. Slone: Molecular regulation, membrane association and secretion of tumor cathepsin B. Apmis 107, 28-37(1999) (Pubitemid 29133520)
    • (1999) APMIS , vol.107 , Issue.1 , pp. 28-37
    • Frosch, B.A.1    Berquin, I.2    Emmert-Buck, M.R.3    Moin, K.4    Sloane, B.E.5
  • 87
    • 12344301866 scopus 로고    scopus 로고
    • Epidermal differentiation: The role of proteases and their inhibitors
    • DOI 10.1078/0171-9335-00388
    • Zeeuwen, P. L.: Epidermal differentiation: the role of proteases and their inhibitors. Eur J Cell Biol 83, 761-73(2004) (Pubitemid 40123840)
    • (2004) European Journal of Cell Biology , vol.83 , Issue.11-12 , pp. 761-773
    • Zeeuwen, P.L.J.M.1
  • 90
    • 29244477512 scopus 로고    scopus 로고
    • The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: Down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin
    • DOI 10.1016/j.bbrc.2005.11.171, PII S0006291X05027038
    • Song J., C. Jie, P. Polk, R. Shridhar, T. Clair, J. Zhang, L. Yin and D. Keppler: The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin. Biochem and Biophy Res Comm 340, 175-182(2006) (Pubitemid 41827662)
    • (2006) Biochemical and Biophysical Research Communications , vol.340 , Issue.1 , pp. 175-182
    • Song, J.1    Jie, C.2    Polk, P.3    Shridhar, R.4    Clair, T.5    Zhang, J.6    Yin, L.7    Keppler, D.8


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