Efficacy of 99mTc-DTPA lung clearance test in the diagnosis of PCP in HIV-Positive patients

Journal of Tropical Pediatrics

Volumn 55, Issue 2, 2009, Pages 97-102

  Deep, Akash ^a,b   Bhure, S U ^a   Bhure, U N ^a   Joshi, S M ^a   Bhatt, B M ^a   Desai, S A ^a   Karayil, S ^a   Deshpande, S D ^a  

^a BYL NAIR CHARITABLE HOSPITAL   (India)

^b NONE   (United Kingdom)

Author keywords

99mTc DTPA lung scan; HIV; Lung clearance; PCP; Pneumocystis carinii pneumonia; TB

Indexed keywords

COTRIMOXAZOLE; PENTETATE TECHNETIUM TC 99M; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ARTERIAL GAS; ARTICLE; BACTERIAL PNEUMONIA; BLOOD CELL COUNT; BLOOD CULTURE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; EARLY DIAGNOSIS; FEMALE; GRAM STAINING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LUNG CLEARANCE; LUNG SCINTISCANNING; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MICROBIOLOGICAL EXAMINATION; NON INVASIVE PROCEDURE; PATIENT SAFETY; PNEUMOCYSTIS PNEUMONIA; PRESCHOOL CHILD; RESPIRATORY TRACT INFECTION; SENSITIVITY AND SPECIFICITY; SPUTUM EXAMINATION; THORAX RADIOGRAPHY; TUBERCULIN TEST; AEROSOL; AIDS RELATED COMPLEX; HUMAN IMMUNODEFICIENCY VIRUS 1; INHALATIONAL DRUG ADMINISTRATION; LUNG; PROSPECTIVE STUDY; SCINTISCANNING;

ADMINISTRATION, INHALATION; AEROSOLS; AIDS-RELATED OPPORTUNISTIC INFECTIONS; CHILD; CHILD, PRESCHOOL; FEMALE; HIV SEROPOSITIVITY; HIV-1; HUMANS; LUNG; MALE; PNEUMONIA, PNEUMOCYSTIS; PROSPECTIVE STUDIES; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M PENTETATE; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION;

EID: 63849124046     PISSN: 01426338     EISSN: 14653664     Source Type: Journal    
DOI: 10.1093/tropej/fmn075     Document Type: Article

References (34)

1. Centers for Disease Control. Acquired immunodeficiency syndrome (AIDS) update - United States. Morb Mortal Wkly Rep 1983;32:309-11.
2. Murray JF, Felton CP, Garay SM, et al. Pulmonary complications of acquired immunodeficiency syndrome. Report of a national heart, lung and blood institute workshop. N Engl J Med 1984;310:168-8.
3. Farthing C. Pneumonia in the acquired immune deficiency syndrome. Br Med J 1985;290:1829.
4. Goodman JL, Tashkin DP. Pneumocystis with normal chest X-ray film and arterial oxygen tension. Early diagnosis in a patient with acquired immune deficiency syndrome. Arch Intern Med 1983;143:1981-2.
5. Bitran J, Bekerman C, Weinstein R, et al. Patterns of Gallium-67 scintigraphy in patients with Acquired Immunodeficiency Syndrome and the AIDS related Complex. J Nucl Med 1987;28:1103-06.
6. Askin F, Katezenstein AL. Pneumocystis infection masquerading as diffuse alveolar damage. Chest 1981;79:420-3.
7. Effros RM, Mason G.R. Measurement of pulmonary epithelial permeability in animals and man. Am Rev Respir Dis 1983;127(Suppl.): 59-65.
8. Mason GR, Duane GB, Effros RM. Rapid clearance of inhaled aerosol of technetium -99m DTPA in patients with Pneumocystis carinii Pneumonia. J Nucl Med 1985;26:59.
9. Jones JG, Minty BD, Beeley JM. Pulmonary epithelial permeability is immediately increased after embolisation with oleic acid but not with neutral fat. Thorax 1982;37:169-74.
10. Jefferies AL, Coates G, Webber CE. Measurement of pulmonary clearance of radioaerosol using a portable sodium iodide probe. J Appl Physiol 1984;57:19081-2.
11. O'Doherty MJ, Page CJ, Craft DN. Lung Tc DTPA transfer: A method for background correction. Nucl Med. Commun 1985;61:209-15.
12. O'Doherty MJ, Page CJ, Craft DN. Regional lung epithelial leakiness in smokers and non-smokers. Nucl Med Commun 1985;6:353-7.
13. Chandra P, Deloney MD, Tuazon CU. Role of special stains in the diagnosis of Pneumocystis carinii infection from bronchial washing specimens in patients with the aquired immunodeficiency syndrome. Acta Cytol 1988;32:105-8.
14. Mattey JE, Fitzpatrick SB, Josephes SH, et al. Bronchoalveloar lavage for PCP in HIV infected children. Ann Allergy Asthma Immunol 1992;63:393.
15. Bye MR, Benstein LJ, Shah K, et al. Diagnostic BAL in children with AIDS. Pediatric Pulmonol 1982;3:425.
16. Rinder Knecht JM, Krauthammer M, Uszler JM, et al. Accelerated clearance of small solutes from the lungs in interstitial lung disease. Am Rev Respir Dis 1980;121:105-17.
17. Chopra SK, Taplin GV, Tashkin DP, et al. Lung clearance of soluble radioaerosols of different molecular weights in systemic sclerosis. Thorax 1979;34:63-7.
18. Mason GR, Effros RM, Uszler JM, et al. Small solute clearance from the lungs of patients with cardiogenic and non cardiogenic pulmonary edema. Chest 1985;88:327-34.
19. Mason GR, Duane GB. Accelerated solute clearance in Pnemocystis carinii pneumonia. Am Rev Respir Dis 1997;135:864-8.
20. Jones JG, Lawer P, Crawley JCW, et al. Increased alveolar epithelial permeability in cigarette smokers. Lancet 1980;1:66-8.
21. Minty BD, Jordan C, Jones JG. Rapid improvement in abnormal permeability after stopping smoking. Br Med J 1981;282:1184-6.
22. Mason GR, Effros RM, Uszlar JM, et al. Rapidly reversible alterations of pulmonary epithelial permeability induced by smoking. Chest 1983;83:6-11.
23. O'Doherty MJ, Page CJ, Bradbeer CS, et al. The place of lung 99mTc DTPA aerosol transfer in the investigation of lung infections in HIV positive patients. Respir Med 1989;83:395-401.
24. Dimian CO, O'Doherty MJ, Ashoe D, et al. Radioactively labeled diethylene triamine penta acetate lung scan in Pneumocystis carinii pneumonia and asymptomatic HIV-positive patients. Int J STD AIDS 1997;8:482-8.
25. Coleman DL, Hattner RS, Luce JM, et al. Correlation between gallium scans and fibreoptic bronchoscopy in patients with suspected Pneumocystis carinii pneumonia and the acquired immune deficiency syndrome. Am Rev Respir Dis 1984;130:1166-9.
26. Tuazon CU, Delaney MD, Simon GL, et al. Utility of gallium-67 scintigraphy and bronchial washings in diagnosis and treatment of patients with the acquired immune deficiency syndrome. Am Rev Respir Dis 1985;(Suppl 5):132-5.
27. Picard C, Meignan M, Rosso J, et al. Technetium-99m DTPA aerosol and gallium scanning in acquired immune deficiency syndrome. Clin Nucl Med 1987;12:501-6.
28. Rosso J, Guillon JM, Parrot A, et al. Technetium-99m-DTPA aerosol and gallium-67 scanning in pulmonary complications of human immunodefiency virus infection. J Nucl Med 1992;33:81-7.
29. Meignan M, Rosso J, Picard C, et al. Aerosol pulmonary scintigraphy. A new test in the diagnostic strategy of pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. Presse Med 1988;17:577-80.
30. O'Doherty MJ, CJ Page, CS Bradbur, et al. Alveolar permeability in HIV antibody positive patients with pneumcystis carinii pneumonia. Gentiurin Med 1987;63:268-70.
31. Rosso J, Picard C, Mayand C, et al. Comparison of Tc DTPA aerosol and Gallium scans in early detection of Pneumocystis carinii pneumonia in acquired immune deficiency syndrome. J Nucl Med 1986;27:951.
32. Ketchum LE. AIDS diagnosis and monitoring improved by radionuclide procedures. J Nucl Med 1985;26:1109-12.
33. Wall BF, Hart D. Revised radiation doses for typical X-ray examinations. Br J Radiol 1997;70:437-9.
34. Parker JA, Coleman RE, Siegel BA, et al. Procedure guideline for lung scintigraphy: 1.0. Society of Nuclear Medicine. J Nucl Med 1996;37:1906-10.