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Volumn 69, Issue 3, 2009, Pages 211-222

Optimizing therapeutic strategies in advanced bladder cancer: Update on chemotherapy and the role of targeted agents

Author keywords

Bladder cancer; Chemotherapy; Cisplatin; Gemcitabine; New agents; Paclitaxel; Urothelial cell cancer

Indexed keywords

ALPHA INTERFERON; ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; GALLIUM; GEFITINIB; GEMCITABINE; IFOSFAMIDE; IXABEPILONE; LAPATINIB; LOBAPLATIN; METHOTREXATE; MOLECULAR MARKER; OXALIPLATIN; PACLITAXEL; PEMETREXED; PIRITREXIM; SORAFENIB; SUNITINIB; TAXANE DERIVATIVE; TRASTUZUMAB; TRIMETREXATE; UNINDEXED DRUG; VANDETANIB; VINBLASTINE; VINFLUNINE;

EID: 63749109609     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2008.06.002     Document Type: Review
Times cited : (48)

References (135)
  • 1
    • 0026625220 scopus 로고
    • A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study
    • Loehrer Sr. P.J., Einhorn L.H., Elson P.J., et al. A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study. J Clin Oncol 10 (1992) 1066-1073
    • (1992) J Clin Oncol , vol.10 , pp. 1066-1073
    • Loehrer Sr., P.J.1    Einhorn, L.H.2    Elson, P.J.3
  • 2
    • 0034859585 scopus 로고    scopus 로고
    • New chemotherapy combinations for advanced bladder cancer
    • Bellmunt J., and Albiol S. New chemotherapy combinations for advanced bladder cancer. Curr Opin Urol 11 (2001) 517-522
    • (2001) Curr Opin Urol , vol.11 , pp. 517-522
    • Bellmunt, J.1    Albiol, S.2
  • 3
    • 0030794516 scopus 로고    scopus 로고
    • Long-term follow-up of a phase III intergroup study of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study
    • Saxman S.B., Propert K.J., Einhorn L.H., et al. Long-term follow-up of a phase III intergroup study of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study. J Clin Oncol 15 (1997) 2564-2569
    • (1997) J Clin Oncol , vol.15 , pp. 2564-2569
    • Saxman, S.B.1    Propert, K.J.2    Einhorn, L.H.3
  • 4
    • 0027482017 scopus 로고
    • Carboplatin-based chemotherapy for bladder cancer
    • Waxman J., and Barton C. Carboplatin-based chemotherapy for bladder cancer. Cancer Treat Rev 19 Suppl. C (1993) 21-25
    • (1993) Cancer Treat Rev , vol.19 , Issue.SUPPL. C , pp. 21-25
    • Waxman, J.1    Barton, C.2
  • 5
    • 0031017367 scopus 로고    scopus 로고
    • Eastern Cooperative Oncology Group phase II trial of ifosfamide in the treatment of previously treated advanced urothelial carcinoma
    • Witte R.S., Elson P., Bono B., et al. Eastern Cooperative Oncology Group phase II trial of ifosfamide in the treatment of previously treated advanced urothelial carcinoma. J Clin Oncol 15 (1997) 589-593
    • (1997) J Clin Oncol , vol.15 , pp. 589-593
    • Witte, R.S.1    Elson, P.2    Bono, B.3
  • 6
    • 15644367397 scopus 로고    scopus 로고
    • Lobaplatin in advanced urothelial tract tumors (EORTC 30931)
    • [abstr 1158]
    • De Mulder P., Sternberg C., Fossa S., et al. Lobaplatin in advanced urothelial tract tumors (EORTC 30931). Proc Am Soc Clin Oncol (1997) [abstr 1158]
    • (1997) Proc Am Soc Clin Oncol
    • De Mulder, P.1    Sternberg, C.2    Fossa, S.3
  • 7
  • 8
    • 0030927578 scopus 로고    scopus 로고
    • Wilding G: phase II trial of oral piritrexim in advanced, previously treated transitional cell cancer of bladder
    • Khorsand M., Lange J., Feun L., Clendeninn N.J., and Collier M. Wilding G: phase II trial of oral piritrexim in advanced, previously treated transitional cell cancer of bladder. Invest New Drugs 15 (1997) 157-163
    • (1997) Invest New Drugs , vol.15 , pp. 157-163
    • Khorsand, M.1    Lange, J.2    Feun, L.3    Clendeninn, N.J.4    Collier, M.5
  • 9
    • 0028174048 scopus 로고
    • An Eastern Cooperative Oncology Group phase II trial of trimetrexate in the treatment of advanced urothelial carcinoma
    • Witte R.S., Elson P., Khandakar J., and Trump D.L. An Eastern Cooperative Oncology Group phase II trial of trimetrexate in the treatment of advanced urothelial carcinoma. Cancer 73 (1994) 688-691
    • (1994) Cancer , vol.73 , pp. 688-691
    • Witte, R.S.1    Elson, P.2    Khandakar, J.3    Trump, D.L.4
  • 10
    • 33745616821 scopus 로고    scopus 로고
    • Gemcitabine in the treatment of advanced transitional cell carcinoma of the urothelium
    • Bellmunt J., Albiol S., de Olano A., et al. Gemcitabine in the treatment of advanced transitional cell carcinoma of the urothelium. Ann Oncol 17 (2006) 113-117
    • (2006) Ann Oncol , vol.17 , pp. 113-117
    • Bellmunt, J.1    Albiol, S.2    de Olano, A.3
  • 11
    • 0029853721 scopus 로고    scopus 로고
    • Paclitaxel in advanced urothelial carcinoma: its role in patients with renal insufficiency and as salvage therapy
    • Dreicer R., Gustin D.M., See W.A., and Williams R.D. Paclitaxel in advanced urothelial carcinoma: its role in patients with renal insufficiency and as salvage therapy. J Urol 156 (1996) 1606-1608
    • (1996) J Urol , vol.156 , pp. 1606-1608
    • Dreicer, R.1    Gustin, D.M.2    See, W.A.3    Williams, R.D.4
  • 12
    • 0031005761 scopus 로고    scopus 로고
    • Phase II trial of docetaxel in patients with advanced or metastatic transitional-cell carcinoma
    • McCaffrey J.A., Hilton S., Mazumdar M., et al. Phase II trial of docetaxel in patients with advanced or metastatic transitional-cell carcinoma. J Clin Oncol 15 (1997) 1853-1857
    • (1997) J Clin Oncol , vol.15 , pp. 1853-1857
    • McCaffrey, J.A.1    Hilton, S.2    Mazumdar, M.3
  • 13
    • 2942540954 scopus 로고    scopus 로고
    • Phase II study of oxaliplatin in patients with inoperable, locally advanced or metastatic transitional cell carcinoma of the urothelial tract (TCC) who have received prior chemotherapy
    • [abstr 1638]
    • Moore M.J., Winquist E., Vokes E.E., et al. Phase II study of oxaliplatin in patients with inoperable, locally advanced or metastatic transitional cell carcinoma of the urothelial tract (TCC) who have received prior chemotherapy. Proc Am Soc Clin Oncol (2003) [abstr 1638]
    • (2003) Proc Am Soc Clin Oncol
    • Moore, M.J.1    Winquist, E.2    Vokes, E.E.3
  • 14
    • 0036125895 scopus 로고    scopus 로고
    • Brief communication: use of the multitargeted antifolate pemetrexed (Alimta) in genitourinary cancer
    • Misset J.L. Brief communication: use of the multitargeted antifolate pemetrexed (Alimta) in genitourinary cancer. Semin Oncol 29 1 Suppl. 3 (2002) 36-39
    • (2002) Semin Oncol , vol.29 , Issue.1 SUPPL. 3 , pp. 36-39
    • Misset, J.L.1
  • 15
    • 44449104798 scopus 로고    scopus 로고
    • Phase II study of single-agent vinflunine in platinum-refractory transitional cell carcinoma of the urothelium
    • [abstr 15543]
    • Vaughn D., Srinvas S., Stadler R., et al. Phase II study of single-agent vinflunine in platinum-refractory transitional cell carcinoma of the urothelium. Proc Am Soc Clin Oncol (2007) [abstr 15543]
    • (2007) Proc Am Soc Clin Oncol
    • Vaughn, D.1    Srinvas, S.2    Stadler, R.3
  • 16
    • 0027999651 scopus 로고
    • Significant activity of paclitaxel in advanced transitional-cell carcinoma of the urothelium: a phase II trial of the Eastern Cooperative Oncology Group
    • Roth B.J., Dreicer R., Einhorn L.H., et al. Significant activity of paclitaxel in advanced transitional-cell carcinoma of the urothelium: a phase II trial of the Eastern Cooperative Oncology Group. J Clin Oncol 12 (1994) 2264-2270
    • (1994) J Clin Oncol , vol.12 , pp. 2264-2270
    • Roth, B.J.1    Dreicer, R.2    Einhorn, L.H.3
  • 17
    • 33947276729 scopus 로고    scopus 로고
    • Chemotherapy for metastatic or unresectable bladder cancer
    • Bellmunt J., and Albiol S. Chemotherapy for metastatic or unresectable bladder cancer. Semin Oncol 34 (2007) 135-144
    • (2007) Semin Oncol , vol.34 , pp. 135-144
    • Bellmunt, J.1    Albiol, S.2
  • 18
    • 0031028244 scopus 로고    scopus 로고
    • Vinblastine, ifosfamide, and gallium nitrate-an active new regimen in patients with advanced carcinoma of the urothelium. A phase II trial of the Eastern Cooperative Oncology Group (E5892)
    • Dreicer R., Propert K.J., Roth, Einhorn L.H., and Loehrer P.J. Vinblastine, ifosfamide, and gallium nitrate-an active new regimen in patients with advanced carcinoma of the urothelium. A phase II trial of the Eastern Cooperative Oncology Group (E5892). Cancer 79 1 (1997) 110-114
    • (1997) Cancer , vol.79 , Issue.1 , pp. 110-114
    • Dreicer, R.1    Propert, K.J.2    Roth3    Einhorn, L.H.4    Loehrer, P.J.5
  • 19
    • 0022360630 scopus 로고
    • Cisplatin, methotrexate, and vinblastine (CMV): an effective chemotherapy regimen for metastatic transitional cell carcinoma of the urinary tract. A Northern California Oncology Group study
    • Harker W.G., Meyers F.J., Freiha F.S., et al. Cisplatin, methotrexate, and vinblastine (CMV): an effective chemotherapy regimen for metastatic transitional cell carcinoma of the urinary tract. A Northern California Oncology Group study. J Clin Oncol 3 (1985) 1463-1470
    • (1985) J Clin Oncol , vol.3 , pp. 1463-1470
    • Harker, W.G.1    Meyers, F.J.2    Freiha, F.S.3
  • 20
    • 0028938652 scopus 로고
    • Advanced bladder cancer: the need to identify new agents in the post-M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) world
    • Roth B.J., and Bajorin D.F. Advanced bladder cancer: the need to identify new agents in the post-M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) world. J Urol 153 (1995) 894-900
    • (1995) J Urol , vol.153 , pp. 894-900
    • Roth, B.J.1    Bajorin, D.F.2
  • 21
    • 0024817806 scopus 로고
    • Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and relapse
    • Sternberg C.N., Yagoda A., Scher H.I., et al. Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and relapse. Cancer 64 (1989) 2448-2458
    • (1989) Cancer , vol.64 , pp. 2448-2458
    • Sternberg, C.N.1    Yagoda, A.2    Scher, H.I.3
  • 22
    • 0026333888 scopus 로고
    • M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for advanced carcinoma of the bladder. The French Federation of Cancer Centers experience
    • Boutan-Laroze A., Mahjoubi M., Droz J.P., et al. M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for advanced carcinoma of the bladder. The French Federation of Cancer Centers experience. Eur J Cancer 27 (1991) 1690-1694
    • (1991) Eur J Cancer , vol.27 , pp. 1690-1694
    • Boutan-Laroze, A.1    Mahjoubi, M.2    Droz, J.P.3
  • 23
    • 0025193076 scopus 로고
    • Usefulness and limitations of methotrexate, vinblastine, doxorubicin and cisplatin for the treatment of advanced urothelial cancer
    • Igawa M., Ohkuchi T., Ueki T., Ueda M., Okada K., and Usui T. Usefulness and limitations of methotrexate, vinblastine, doxorubicin and cisplatin for the treatment of advanced urothelial cancer. J Urol 144 (1990) 662-665
    • (1990) J Urol , vol.144 , pp. 662-665
    • Igawa, M.1    Ohkuchi, T.2    Ueki, T.3    Ueda, M.4    Okada, K.5    Usui, T.6
  • 24
    • 0029961445 scopus 로고    scopus 로고
    • Survival of patients with advanced urothelial cancer treated with cisplatin-based chemotherapy
    • Fossa S.D., Sternberg C., Scher H.I., et al. Survival of patients with advanced urothelial cancer treated with cisplatin-based chemotherapy. Br J Cancer 74 (1996) 1655-1659
    • (1996) Br J Cancer , vol.74 , pp. 1655-1659
    • Fossa, S.D.1    Sternberg, C.2    Scher, H.I.3
  • 25
    • 0025297496 scopus 로고
    • A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors
    • Logothetis C.J., Dexeus F.H., Finn L., et al. A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors. J Clin Oncol 8 (1990) 1050-1055
    • (1990) J Clin Oncol , vol.8 , pp. 1050-1055
    • Logothetis, C.J.1    Dexeus, F.H.2    Finn, L.3
  • 26
    • 0030710534 scopus 로고    scopus 로고
    • Carboplatin-based versus cisplatin-based chemotherapy in the treatment of surgically incurable advanced bladder carcinoma
    • Bellmunt J., Ribas A., Eres N., et al. Carboplatin-based versus cisplatin-based chemotherapy in the treatment of surgically incurable advanced bladder carcinoma. Cancer 80 (1997) 1966-1972
    • (1997) Cancer , vol.80 , pp. 1966-1972
    • Bellmunt, J.1    Ribas, A.2    Eres, N.3
  • 27
    • 0031712489 scopus 로고    scopus 로고
    • A randomized trial comparing methotrexate and vinblastine (MV) with cisplatin, methotrexate and vinblastine (CMV) in advanced transitional cell carcinoma: results and a report on prognostic factors in a Medical Research Council study. MRC Advanced Bladder Cancer Working Party
    • Mead G.M., Russell M., Clark P., et al. A randomized trial comparing methotrexate and vinblastine (MV) with cisplatin, methotrexate and vinblastine (CMV) in advanced transitional cell carcinoma: results and a report on prognostic factors in a Medical Research Council study. MRC Advanced Bladder Cancer Working Party. Br J Cancer 78 (1998) 1067-1075
    • (1998) Br J Cancer , vol.78 , pp. 1067-1075
    • Mead, G.M.1    Russell, M.2    Clark, P.3
  • 28
    • 0028359274 scopus 로고
    • Escalated dosages of methotrexate, vinblastine, doxorubicin, and cisplatin plus recombinant human granulocyte colony-stimulating factor in advanced urothelial carcinoma: an Eastern Cooperative Oncology Group trial
    • Loehrer Sr. P.J., Elson P., Dreicer R., et al. Escalated dosages of methotrexate, vinblastine, doxorubicin, and cisplatin plus recombinant human granulocyte colony-stimulating factor in advanced urothelial carcinoma: an Eastern Cooperative Oncology Group trial. J Clin Oncol 12 (1994) 483-488
    • (1994) J Clin Oncol , vol.12 , pp. 483-488
    • Loehrer Sr., P.J.1    Elson, P.2    Dreicer, R.3
  • 29
    • 0029131434 scopus 로고
    • Escalated MVAC with or without recombinant human granulocyte-macrophage colony-stimulating factor for the initial treatment of advanced malignant urothelial tumors: results of a randomized trial
    • Logothetis C.J., Finn L.D., Smith T., et al. Escalated MVAC with or without recombinant human granulocyte-macrophage colony-stimulating factor for the initial treatment of advanced malignant urothelial tumors: results of a randomized trial. J Clin Oncol 13 (1995) 2272-2277
    • (1995) J Clin Oncol , vol.13 , pp. 2272-2277
    • Logothetis, C.J.1    Finn, L.D.2    Smith, T.3
  • 30
    • 0027528981 scopus 로고
    • Effect of relative cumulative dose-intensity on survival of patients with urothelial cancer treated with M-VAC
    • Scher H.I., Geller N.L., Curley T., and Tao Y. Effect of relative cumulative dose-intensity on survival of patients with urothelial cancer treated with M-VAC. J Clin Oncol 11 (1993) 400-407
    • (1993) J Clin Oncol , vol.11 , pp. 400-407
    • Scher, H.I.1    Geller, N.L.2    Curley, T.3    Tao, Y.4
  • 31
    • 0027460092 scopus 로고
    • Dose-intensification of MVAC with recombinant granulocyte colony-stimulating factor as initial therapy in advanced urothelial cancer
    • Seidman A.D., Scher H.I., Gabrilove J.L., et al. Dose-intensification of MVAC with recombinant granulocyte colony-stimulating factor as initial therapy in advanced urothelial cancer. J Clin Oncol 11 (1993) 408-414
    • (1993) J Clin Oncol , vol.11 , pp. 408-414
    • Seidman, A.D.1    Scher, H.I.2    Gabrilove, J.L.3
  • 32
    • 0023945042 scopus 로고
    • Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional-cell carcinoma of the urothelium
    • Gabrilove J.L., Jakubowski A., Scher H., et al. Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional-cell carcinoma of the urothelium. N Engl J Med 318 22 (1988) 1414-1422
    • (1988) N Engl J Med , vol.318 , Issue.22 , pp. 1414-1422
    • Gabrilove, J.L.1    Jakubowski, A.2    Scher, H.3
  • 33
    • 0035873915 scopus 로고    scopus 로고
    • Randomized phase III trial of high-dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: European Organization for Research and Treatment of Cancer Protocol no. 30924
    • Sternberg C.N., de Mulder P.H., Schornagel J.H., et al. Randomized phase III trial of high-dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: European Organization for Research and Treatment of Cancer Protocol no. 30924. J Clin Oncol 19 (2001) 2638-2646
    • (2001) J Clin Oncol , vol.19 , pp. 2638-2646
    • Sternberg, C.N.1    de Mulder, P.H.2    Schornagel, J.H.3
  • 34
    • 29144434734 scopus 로고    scopus 로고
    • Seven year update of an EORTC phase III trial of high-dose intensity M-VAC chemotherapy and G-CSF versus classic M-VAC in advanced urothelial tract tumours
    • Sternberg C.N., de Mulder P., Schornagel J.H., et al. Seven year update of an EORTC phase III trial of high-dose intensity M-VAC chemotherapy and G-CSF versus classic M-VAC in advanced urothelial tract tumours. Eur J Cancer 42 (2006) 50-54
    • (2006) Eur J Cancer , vol.42 , pp. 50-54
    • Sternberg, C.N.1    de Mulder, P.2    Schornagel, J.H.3
  • 36
    • 17444437833 scopus 로고    scopus 로고
    • Phase II trial of gemcitabine plus cisplatin in patients with metastatic urothelial cancer
    • Kaufman D., Raghavan D., Carducci M., et al. Phase II trial of gemcitabine plus cisplatin in patients with metastatic urothelial cancer. J Clin Oncol 18 (2000) 1921-1927
    • (2000) J Clin Oncol , vol.18 , pp. 1921-1927
    • Kaufman, D.1    Raghavan, D.2    Carducci, M.3
  • 37
    • 0032858246 scopus 로고    scopus 로고
    • Gemcitabine plus cisplatin, an active regimen in advanced urothelial cancer: a phase II trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore M.J., Winquist E.W., Murray N., et al. Gemcitabine plus cisplatin, an active regimen in advanced urothelial cancer: a phase II trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 17 (1999) 2876-2881
    • (1999) J Clin Oncol , vol.17 , pp. 2876-2881
    • Moore, M.J.1    Winquist, E.W.2    Murray, N.3
  • 38
    • 0033390548 scopus 로고    scopus 로고
    • Weekly gemcitabine and cisplatin combination therapy in patients with transitional cell carcinoma of the urothelium: a phase II clinical trial
    • von der Maase H., Andersen L., Crino L., Weinknecht S., and Dogliotti L. Weekly gemcitabine and cisplatin combination therapy in patients with transitional cell carcinoma of the urothelium: a phase II clinical trial. Ann Oncol 10 (1999) 1461-1465
    • (1999) Ann Oncol , vol.10 , pp. 1461-1465
    • von der Maase, H.1    Andersen, L.2    Crino, L.3    Weinknecht, S.4    Dogliotti, L.5
  • 39
    • 0033857218 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study
    • von der Maase H., Hansen S.W., Roberts J.T., et al. Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study. J Clin Oncol 18 (2000) 3068-3077
    • (2000) J Clin Oncol , vol.18 , pp. 3068-3077
    • von der Maase, H.1    Hansen, S.W.2    Roberts, J.T.3
  • 40
    • 0033789641 scopus 로고    scopus 로고
    • Phase II study of paclitaxel and cisplatin for advanced urothelial cancer
    • Burch P.A., Richardson R.L., Cha S.S., et al. Phase II study of paclitaxel and cisplatin for advanced urothelial cancer. J Urol 164 (2000) 1538-1542
    • (2000) J Urol , vol.164 , pp. 1538-1542
    • Burch, P.A.1    Richardson, R.L.2    Cha, S.S.3
  • 41
    • 0033994219 scopus 로고    scopus 로고
    • Phase II study of cisplatin and paclitaxel in advanced carcinoma of the urothelium: an Eastern Cooperative Oncology Group Study
    • Dreicer R., Manola J., Roth B.J., Cohen M.B., Hatfield A.K., and Wilding G. Phase II study of cisplatin and paclitaxel in advanced carcinoma of the urothelium: an Eastern Cooperative Oncology Group Study. J Clin Oncol 18 (2000) 1058-1061
    • (2000) J Clin Oncol , vol.18 , pp. 1058-1061
    • Dreicer, R.1    Manola, J.2    Roth, B.J.3    Cohen, M.B.4    Hatfield, A.K.5    Wilding, G.6
  • 42
    • 0002575775 scopus 로고    scopus 로고
    • Phase II trial of paclitaxel and cisplatin for metastatic or locally unresectable urothelial cancer
    • [abstr 617]
    • Murphy B.A., Johnson D.R., Smith J., et al. Phase II trial of paclitaxel and cisplatin for metastatic or locally unresectable urothelial cancer. Proc Am Soc Clin Oncol (1996) [abstr 617]
    • (1996) Proc Am Soc Clin Oncol
    • Murphy, B.A.1    Johnson, D.R.2    Smith, J.3
  • 43
    • 0032779101 scopus 로고    scopus 로고
    • Docetaxel and cisplatin combination chemotherapy in advanced carcinoma of the urothelium: a multicenter phase II study of the Hellenic Cooperative Oncology Group
    • Dimopoulos M.A., Bakoyannis C., Georgoulias V., et al. Docetaxel and cisplatin combination chemotherapy in advanced carcinoma of the urothelium: a multicenter phase II study of the Hellenic Cooperative Oncology Group. Ann Oncol 10 (1999) 1385-1388
    • (1999) Ann Oncol , vol.10 , pp. 1385-1388
    • Dimopoulos, M.A.1    Bakoyannis, C.2    Georgoulias, V.3
  • 44
    • 18244396648 scopus 로고    scopus 로고
    • Phase II multicentre study of docetaxel plus cisplatin in patients with advanced urothelial cancer
    • Garcia del Muro X., Marcuello E., Guma J., et al. Phase II multicentre study of docetaxel plus cisplatin in patients with advanced urothelial cancer. Br J Cancer 86 (2002) 326-330
    • (2002) Br J Cancer , vol.86 , pp. 326-330
    • Garcia del Muro, X.1    Marcuello, E.2    Guma, J.3
  • 45
    • 0031752909 scopus 로고    scopus 로고
    • Docetaxel and cisplatin in metastatic urothelial cancer: a phase II study
    • Sengelov L., Kamby C., Lund B., and Engelholm S.A. Docetaxel and cisplatin in metastatic urothelial cancer: a phase II study. J Clin Oncol 16 (1998) 3392-3397
    • (1998) J Clin Oncol , vol.16 , pp. 3392-3397
    • Sengelov, L.1    Kamby, C.2    Lund, B.3    Engelholm, S.A.4
  • 46
    • 1342268941 scopus 로고    scopus 로고
    • Docetaxel and cisplatin with granulocyte colony-stimulating factor (G-CSF) versus MVAC with G-CSF in advanced urothelial carcinoma: a multicenter, randomized, phase III study from the Hellenic Cooperative Oncology Group
    • Bamias A., Aravantinos G., Deliveliotis C., et al. Docetaxel and cisplatin with granulocyte colony-stimulating factor (G-CSF) versus MVAC with G-CSF in advanced urothelial carcinoma: a multicenter, randomized, phase III study from the Hellenic Cooperative Oncology Group. J Clin Oncol 22 (2004) 220-228
    • (2004) J Clin Oncol , vol.22 , pp. 220-228
    • Bamias, A.1    Aravantinos, G.2    Deliveliotis, C.3
  • 47
    • 63749085498 scopus 로고    scopus 로고
    • NCCN Practice Guidelines in Oncology-v.2.2008.
    • NCCN Practice Guidelines in Oncology-v.2.2008.
  • 48
    • 45149134445 scopus 로고    scopus 로고
    • Invasive bladder cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up
    • Bellmunt J., Albiol S., and Kataja V. Invasive bladder cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 19 (2008) 1147-1148
    • (2008) Ann Oncol , vol.19 , pp. 1147-1148
    • Bellmunt, J.1    Albiol, S.2    Kataja, V.3
  • 49
    • 0031803705 scopus 로고    scopus 로고
    • Phase II trial of paclitaxel and carboplatin in the treatment of advanced urothelial carcinoma
    • Redman B.G., Smith D.C., Flaherty L., Du W., and Hussain M. Phase II trial of paclitaxel and carboplatin in the treatment of advanced urothelial carcinoma. J Clin Oncol 16 (1998) 1844-1848
    • (1998) J Clin Oncol , vol.16 , pp. 1844-1848
    • Redman, B.G.1    Smith, D.C.2    Flaherty, L.3    Du, W.4    Hussain, M.5
  • 50
    • 0342758712 scopus 로고    scopus 로고
    • Southwest Oncology Group Study of paclitaxel and carboplatin for advanced transitional-cell carcinoma: the importance of survival as a clinical trial end point
    • Small E.J., Lew D., Redman B.G., et al. Southwest Oncology Group Study of paclitaxel and carboplatin for advanced transitional-cell carcinoma: the importance of survival as a clinical trial end point. J Clin Oncol 18 (2000) 2537-2544
    • (2000) J Clin Oncol , vol.18 , pp. 2537-2544
    • Small, E.J.1    Lew, D.2    Redman, B.G.3
  • 51
    • 0031962154 scopus 로고    scopus 로고
    • Paclitaxel plus carboplatin in advanced carcinoma of the urothelium: an active and tolerable outpatient regimen
    • Vaughn D.J., Malkowicz S.B., Zoltick B., et al. Paclitaxel plus carboplatin in advanced carcinoma of the urothelium: an active and tolerable outpatient regimen. J Clin Oncol 16 (1998) 255-260
    • (1998) J Clin Oncol , vol.16 , pp. 255-260
    • Vaughn, D.J.1    Malkowicz, S.B.2    Zoltick, B.3
  • 52
    • 1842477465 scopus 로고    scopus 로고
    • Phase III trial of methotrexate, vinblastine, doxorubicin, and cisplatin versus carboplatin and paclitaxel in patients with advanced carcinoma of the urothelium
    • Dreicer R., Manola J., Roth B.J., et al. Phase III trial of methotrexate, vinblastine, doxorubicin, and cisplatin versus carboplatin and paclitaxel in patients with advanced carcinoma of the urothelium. Cancer 100 (2004) 1639-1645
    • (2004) Cancer , vol.100 , pp. 1639-1645
    • Dreicer, R.1    Manola, J.2    Roth, B.J.3
  • 53
    • 0034773203 scopus 로고    scopus 로고
    • A feasibility study of carboplatin with fixed dose of gemcitabine in "unfit" patients with advanced bladder cancer
    • Bellmunt J., de Wit R., Albanell J., and Baselga J. A feasibility study of carboplatin with fixed dose of gemcitabine in "unfit" patients with advanced bladder cancer. Eur J Cancer 37 (2001) 2212-2215
    • (2001) Eur J Cancer , vol.37 , pp. 2212-2215
    • Bellmunt, J.1    de Wit, R.2    Albanell, J.3    Baselga, J.4
  • 54
    • 0345381984 scopus 로고    scopus 로고
    • Gemcitabine and carboplatin in advanced transitional cell carcinoma of the urinary tract: an alternative therapy
    • Nogue-Aliguer M., Carles J., Arrivi A., et al. Gemcitabine and carboplatin in advanced transitional cell carcinoma of the urinary tract: an alternative therapy. Cancer 97 (2003) 2180-2186
    • (2003) Cancer , vol.97 , pp. 2180-2186
    • Nogue-Aliguer, M.1    Carles, J.2    Arrivi, A.3
  • 55
    • 0034910874 scopus 로고    scopus 로고
    • Carboplatin and gemcitabine in metastatic transitional cell carcinoma of the urothelium: effective treatment of patients with poor prognostic features
    • Shannon C., Crombie C., Brooks A., Lau H., Drummond M., and Gurney H. Carboplatin and gemcitabine in metastatic transitional cell carcinoma of the urothelium: effective treatment of patients with poor prognostic features. Ann Oncol 12 (2001) 947-952
    • (2001) Ann Oncol , vol.12 , pp. 947-952
    • Shannon, C.1    Crombie, C.2    Brooks, A.3    Lau, H.4    Drummond, M.5    Gurney, H.6
  • 56
    • 2942514256 scopus 로고    scopus 로고
    • Phase II randomized trial of gemcitabine plus cisplatin (GP) and gemcitabine plus carboplatin (GC) in patients (pts) with advanced or metastatic transitional cell carcinoma of the urothelium (TCCU)
    • [abstr 1543]
    • Carteni G., Dogliotti L., Crucitta E., et al. Phase II randomized trial of gemcitabine plus cisplatin (GP) and gemcitabine plus carboplatin (GC) in patients (pts) with advanced or metastatic transitional cell carcinoma of the urothelium (TCCU). Proc Am Soc Clin Oncol 22 (2003) 384 [abstr 1543]
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 384
    • Carteni, G.1    Dogliotti, L.2    Crucitta, E.3
  • 57
    • 0030023088 scopus 로고    scopus 로고
    • Comparison between a cisplatin-containing regimen and a carboplatin-containing regimen for recurrent or metastatic bladder cancer patients. A randomized phase II study
    • Petrioli R., Frediani B., Manganelli A., et al. Comparison between a cisplatin-containing regimen and a carboplatin-containing regimen for recurrent or metastatic bladder cancer patients. A randomized phase II study. Cancer 77 (1996) 344-351
    • (1996) Cancer , vol.77 , pp. 344-351
    • Petrioli, R.1    Frediani, B.2    Manganelli, A.3
  • 58
    • 34548181558 scopus 로고    scopus 로고
    • Gemcitabine and oxaliplatin combination: a multicenter phase II trial in unfit patients with locally advanced or metastatic urothelial cancer
    • Carles J., Esteban E., Climent M., et al. Gemcitabine and oxaliplatin combination: a multicenter phase II trial in unfit patients with locally advanced or metastatic urothelial cancer. Ann Oncol 18 (2007) 1359-1362
    • (2007) Ann Oncol , vol.18 , pp. 1359-1362
    • Carles, J.1    Esteban, E.2    Climent, M.3
  • 59
    • 0038538449 scopus 로고    scopus 로고
    • Gemcitabine and oxaliplatin in advanced transitional cell carcinoma of the urothelium: a pilot study
    • Culine S., Rebillard X., Iborra F., et al. Gemcitabine and oxaliplatin in advanced transitional cell carcinoma of the urothelium: a pilot study. Anticancer Res 23 (2003) 1903-1906
    • (2003) Anticancer Res , vol.23 , pp. 1903-1906
    • Culine, S.1    Rebillard, X.2    Iborra, F.3
  • 60
    • 33646858090 scopus 로고    scopus 로고
    • A phase II monocentric study of oxaliplatin in combination with gemcitabine (GEMOX) in patients with advanced/metastatic transitional cell carcinoma (TCC) of the urothelial tract
    • Theodore C., Bidault F., Bouvet-Forteau N., et al. A phase II monocentric study of oxaliplatin in combination with gemcitabine (GEMOX) in patients with advanced/metastatic transitional cell carcinoma (TCC) of the urothelial tract. Ann Oncol 17 (2006) 990-994
    • (2006) Ann Oncol , vol.17 , pp. 990-994
    • Theodore, C.1    Bidault, F.2    Bouvet-Forteau, N.3
  • 61
    • 4244198798 scopus 로고    scopus 로고
    • Gemcitabine (G) and paclitaxel (P) every two weeks (GP2w): a completed multicenter phase II trial in locally advanced or metastatic urothelial cancer (UC)
    • [abstr 767]
    • Kaufman D.S., Carducci M.A., Kuzel T., et al. Gemcitabine (G) and paclitaxel (P) every two weeks (GP2w): a completed multicenter phase II trial in locally advanced or metastatic urothelial cancer (UC). Proc Am Soc Clin Oncol (2002) [abstr 767]
    • (2002) Proc Am Soc Clin Oncol
    • Kaufman, D.S.1    Carducci, M.A.2    Kuzel, T.3
  • 62
    • 14544306954 scopus 로고    scopus 로고
    • Weekly paclitaxel and gemcitabine in advanced transitional-cell carcinoma of the urothelium: a phase II Hoosier Oncology Group study
    • Li J., Juliar B., Yiannoutsos C., et al. Weekly paclitaxel and gemcitabine in advanced transitional-cell carcinoma of the urothelium: a phase II Hoosier Oncology Group study. J Clin Oncol 23 (2005) 1185-1191
    • (2005) J Clin Oncol , vol.23 , pp. 1185-1191
    • Li, J.1    Juliar, B.2    Yiannoutsos, C.3
  • 63
    • 0035876046 scopus 로고    scopus 로고
    • Paclitaxel and gemcitabine chemotherapy for advanced transitional-cell carcinoma of the urothelial tract: a phase II trial of the Minnie pearl cancer research network
    • Meluch A.A., Greco F.A., Burris III H.A., et al. Paclitaxel and gemcitabine chemotherapy for advanced transitional-cell carcinoma of the urothelial tract: a phase II trial of the Minnie pearl cancer research network. J Clin Oncol 19 (2001) 3018-3024
    • (2001) J Clin Oncol , vol.19 , pp. 3018-3024
    • Meluch, A.A.1    Greco, F.A.2    Burris III, H.A.3
  • 64
    • 0035892761 scopus 로고    scopus 로고
    • Chemotherapy with an every-2-week regimen of gemcitabine and paclitaxel in patients with transitional cell carcinoma who have received prior cisplatin-based therapy
    • Sternberg C.N., Calabro F., Pizzocaro G., Marini L., Schnetzer S., and Sella A. Chemotherapy with an every-2-week regimen of gemcitabine and paclitaxel in patients with transitional cell carcinoma who have received prior cisplatin-based therapy. Cancer 92 (2001) 2993-2998
    • (2001) Cancer , vol.92 , pp. 2993-2998
    • Sternberg, C.N.1    Calabro, F.2    Pizzocaro, G.3    Marini, L.4    Schnetzer, S.5    Sella, A.6
  • 65
    • 17044387754 scopus 로고    scopus 로고
    • A multi-institutional phase II trial of gemcitabine plus paclitaxel in patients with locally advanced or metastatic urothelial cancer
    • Kaufman D.S., Carducci M.A., Kuzel T.M., et al. A multi-institutional phase II trial of gemcitabine plus paclitaxel in patients with locally advanced or metastatic urothelial cancer. Urol Oncol 22 (2004) 393-397
    • (2004) Urol Oncol , vol.22 , pp. 393-397
    • Kaufman, D.S.1    Carducci, M.A.2    Kuzel, T.M.3
  • 66
    • 14944380034 scopus 로고    scopus 로고
    • Gemcitabine and docetaxel as first-line treatment for advanced urothelial carcinoma: a phase II study
    • Ardavanis A., Tryfonopoulos D., Alexopoulos A., Kandylis C., Lainakis G., and Rigatos G. Gemcitabine and docetaxel as first-line treatment for advanced urothelial carcinoma: a phase II study. Br J Cancer 92 (2005) 645-650
    • (2005) Br J Cancer , vol.92 , pp. 645-650
    • Ardavanis, A.1    Tryfonopoulos, D.2    Alexopoulos, A.3    Kandylis, C.4    Lainakis, G.5    Rigatos, G.6
  • 67
    • 33845686332 scopus 로고    scopus 로고
    • Docetaxel and gemcitabine combination therapy in advanced transitional cell carcinoma of the urothelium: results of a phase II and pharmacologic study
    • Dumez H., Martens M., Selleslach J., et al. Docetaxel and gemcitabine combination therapy in advanced transitional cell carcinoma of the urothelium: results of a phase II and pharmacologic study. Anticancer Drugs 18 (2007) 211-218
    • (2007) Anticancer Drugs , vol.18 , pp. 211-218
    • Dumez, H.1    Martens, M.2    Selleslach, J.3
  • 68
    • 0142150098 scopus 로고    scopus 로고
    • A phase II study of gemcitabine and docetaxel therapy in patients with advanced urothelial carcinoma
    • Gitlitz B.J., Baker C., Chapman Y., et al. A phase II study of gemcitabine and docetaxel therapy in patients with advanced urothelial carcinoma. Cancer 98 (2003) 1863-1869
    • (2003) Cancer , vol.98 , pp. 1863-1869
    • Gitlitz, B.J.1    Baker, C.2    Chapman, Y.3
  • 69
    • 63749085074 scopus 로고    scopus 로고
    • Phase II trial of pemetrexed disodium and gemcitabine in advanced carcinoma of the urothelium: a trial of the Eastern Cooperative Oncology Group
    • [abstr 5079]
    • Li S., Dreicer R., Roth B., et al. Phase II trial of pemetrexed disodium and gemcitabine in advanced carcinoma of the urothelium: a trial of the Eastern Cooperative Oncology Group. Proc Am Soc Clin Oncol (2007) [abstr 5079]
    • (2007) Proc Am Soc Clin Oncol
    • Li, S.1    Dreicer, R.2    Roth, B.3
  • 70
    • 33749605418 scopus 로고    scopus 로고
    • A phase II trial of pemetrexed plus gemcitabine in locally advanced and/or metastatic transitional cell carcinoma of the urothelium
    • von der Maase H., Lehmann J., Gravis G., et al. A phase II trial of pemetrexed plus gemcitabine in locally advanced and/or metastatic transitional cell carcinoma of the urothelium. Ann Oncol 17 (2006) 1533-1538
    • (2006) Ann Oncol , vol.17 , pp. 1533-1538
    • von der Maase, H.1    Lehmann, J.2    Gravis, G.3
  • 71
    • 0034177933 scopus 로고    scopus 로고
    • Ifosfamide, paclitaxel, and cisplatin for patients with advanced transitional cell carcinoma of the urothelial tract: final report of a phase II trial evaluating two dosing schedules
    • Bajorin D.F., McCaffrey J.A., Dodd P.M., et al. Ifosfamide, paclitaxel, and cisplatin for patients with advanced transitional cell carcinoma of the urothelial tract: final report of a phase II trial evaluating two dosing schedules. Cancer 88 (2000) 1671-1678
    • (2000) Cancer , vol.88 , pp. 1671-1678
    • Bajorin, D.F.1    McCaffrey, J.A.2    Dodd, P.M.3
  • 72
    • 0033956934 scopus 로고    scopus 로고
    • Phase I evaluation of sequential doxorubicin gemcitabine then ifosfamide paclitaxel cisplatin for patients with unresectable or metastatic transitional-cell carcinoma of the urothelial tract
    • Dodd P.M., McCaffrey J.A., Hilton S., et al. Phase I evaluation of sequential doxorubicin gemcitabine then ifosfamide paclitaxel cisplatin for patients with unresectable or metastatic transitional-cell carcinoma of the urothelial tract. J Clin Oncol 18 (2000) 840-846
    • (2000) J Clin Oncol , vol.18 , pp. 840-846
    • Dodd, P.M.1    McCaffrey, J.A.2    Hilton, S.3
  • 74
    • 0001666051 scopus 로고    scopus 로고
    • Phase I/II sequential doxorubicin plus gemcitabine followed by paclitaxel plus carboplatin in patients with transitional cell carcinoma and impaired renal function
    • [abstr 1423]
    • Novick S., Higgins G., Hilton S., et al. Phase I/II sequential doxorubicin plus gemcitabine followed by paclitaxel plus carboplatin in patients with transitional cell carcinoma and impaired renal function. Proc Am Soc Clin Oncol (2000) [abstr 1423]
    • (2000) Proc Am Soc Clin Oncol
    • Novick, S.1    Higgins, G.2    Hilton, S.3
  • 75
    • 0034666030 scopus 로고    scopus 로고
    • Phase I-II study of paclitaxel, cisplatin, and gemcitabine in advanced transitional-cell carcinoma of the urothelium. Spanish Oncology Genitourinary Group
    • Bellmunt J., Guillem V., Paz-Ares L., et al. Phase I-II study of paclitaxel, cisplatin, and gemcitabine in advanced transitional-cell carcinoma of the urothelium. Spanish Oncology Genitourinary Group. J Clin Oncol 18 (2000) 3247-3255
    • (2000) J Clin Oncol , vol.18 , pp. 3247-3255
    • Bellmunt, J.1    Guillem, V.2    Paz-Ares, L.3
  • 76
    • 36549023828 scopus 로고    scopus 로고
    • Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy; EORTC30987/Intergroup Study
    • [LBA5030]
    • Bellmunt J., von der Maase H., Mead G., et al. Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy; EORTC30987/Intergroup Study. Proc Am Soc Clin Oncol (2007) [LBA5030]
    • (2007) Proc Am Soc Clin Oncol
    • Bellmunt, J.1    von der Maase, H.2    Mead, G.3
  • 77
    • 21144456526 scopus 로고    scopus 로고
    • Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma
    • Catto J.W., Azzouzi A.R., Rehman I., et al. Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma. J Clin Oncol 23 (2005) 2903-2910
    • (2005) J Clin Oncol , vol.23 , pp. 2903-2910
    • Catto, J.W.1    Azzouzi, A.R.2    Rehman, I.3
  • 78
    • 0035339940 scopus 로고    scopus 로고
    • Combination paclitaxel, carboplatin, and gemcitabine is an active treatment for advanced urothelial cancer
    • Hussain M., Vaishampayan U., Du W., Redman B., and Smith D.C. Combination paclitaxel, carboplatin, and gemcitabine is an active treatment for advanced urothelial cancer. J Clin Oncol 19 (2001) 2527-2533
    • (2001) J Clin Oncol , vol.19 , pp. 2527-2533
    • Hussain, M.1    Vaishampayan, U.2    Du, W.3    Redman, B.4    Smith, D.C.5
  • 79
    • 18844386761 scopus 로고    scopus 로고
    • Paclitaxel, carboplatin, and gemcitabine in the treatment of patients with advanced transitional cell carcinoma of the urothelium
    • Hainsworth J.D., Meluch A.A., Litchy S., et al. Paclitaxel, carboplatin, and gemcitabine in the treatment of patients with advanced transitional cell carcinoma of the urothelium. Cancer 103 (2005) 2298-2303
    • (2005) Cancer , vol.103 , pp. 2298-2303
    • Hainsworth, J.D.1    Meluch, A.A.2    Litchy, S.3
  • 80
    • 0034017584 scopus 로고    scopus 로고
    • Phase I/II study of paclitaxel, carboplatin, and methotrexate in advanced transitional cell carcinoma: a well-tolerated regimen with activity independent of p53 mutation
    • Edelman M.J., Meyers F.J., Miller T.R., Williams S.G., Gandour-Edwards R., and deVere White R.W. Phase I/II study of paclitaxel, carboplatin, and methotrexate in advanced transitional cell carcinoma: a well-tolerated regimen with activity independent of p53 mutation. Urology 55 (2000) 521-525
    • (2000) Urology , vol.55 , pp. 521-525
    • Edelman, M.J.1    Meyers, F.J.2    Miller, T.R.3    Williams, S.G.4    Gandour-Edwards, R.5    deVere White, R.W.6
  • 81
    • 0028877082 scopus 로고
    • Paclitaxel, cisplatin and methotrexate combination chemotherapy is active in the treatment of refractory urothelial malignancies
    • Tu S.M., Hossan E., Amato R., Kilbourn R., and Logothetis C.J. Paclitaxel, cisplatin and methotrexate combination chemotherapy is active in the treatment of refractory urothelial malignancies. J Urol 154 (1995) 1719-1722
    • (1995) J Urol , vol.154 , pp. 1719-1722
    • Tu, S.M.1    Hossan, E.2    Amato, R.3    Kilbourn, R.4    Logothetis, C.J.5
  • 82
    • 0033971790 scopus 로고    scopus 로고
    • Chemotherapy with cisplatin, epirubicin and docetaxel in transitional cell urothelial cancer. Phase II trial
    • Pectasides D., Visvikis A., Aspropotamitis A., et al. Chemotherapy with cisplatin, epirubicin and docetaxel in transitional cell urothelial cancer. Phase II trial. Eur J Cancer 36 (2000) 74-79
    • (2000) Eur J Cancer , vol.36 , pp. 74-79
    • Pectasides, D.1    Visvikis, A.2    Aspropotamitis, A.3
  • 83
    • 0013239161 scopus 로고    scopus 로고
    • Platinum free combination chemotherapy in locally advanced and metastatic transitional cell carcinoma: phase I/II trial of gemcitabine, paclitaxel, methotrexate
    • [abstr 767]
    • Law L.Y., Lara P.N., Meyers F.J., et al. Platinum free combination chemotherapy in locally advanced and metastatic transitional cell carcinoma: phase I/II trial of gemcitabine, paclitaxel, methotrexate. Proc Am Soc Clin Oncol (2001) [abstr 767]
    • (2001) Proc Am Soc Clin Oncol
    • Law, L.Y.1    Lara, P.N.2    Meyers, F.J.3
  • 84
    • 0036052170 scopus 로고    scopus 로고
    • Feasibility trial of methotrexate-paclitaxel as a second line therapy in advanced urothelial cancer
    • Bellmunt J., Cos J., Cleries R., et al. Feasibility trial of methotrexate-paclitaxel as a second line therapy in advanced urothelial cancer. Cancer Invest 20 (2002) 673-685
    • (2002) Cancer Invest , vol.20 , pp. 673-685
    • Bellmunt, J.1    Cos, J.2    Cleries, R.3
  • 85
    • 14544294549 scopus 로고    scopus 로고
    • FOLFOX-4 in pre-treated patients with advanced transitional cell carcinoma of the bladder
    • Di Lorenzo G., Autorino R., Giordano A., et al. FOLFOX-4 in pre-treated patients with advanced transitional cell carcinoma of the bladder. Jpn J Clin Oncol 34 (2004) 747-750
    • (2004) Jpn J Clin Oncol , vol.34 , pp. 747-750
    • Di Lorenzo, G.1    Autorino, R.2    Giordano, A.3
  • 86
    • 0031786379 scopus 로고    scopus 로고
    • Docetaxel (Taxotere): an active agent in metastatic urothelial cancer; results of a phase II study in non-chemotherapy-pretreated patients
    • de Wit R., Kruit W.H., Stoter G., de Boer M., Kerger J., and Verweij J. Docetaxel (Taxotere): an active agent in metastatic urothelial cancer; results of a phase II study in non-chemotherapy-pretreated patients. Br J Cancer 78 (1998) 1342-1345
    • (1998) Br J Cancer , vol.78 , pp. 1342-1345
    • de Wit, R.1    Kruit, W.H.2    Stoter, G.3    de Boer, M.4    Kerger, J.5    Verweij, J.6
  • 87
    • 34547865354 scopus 로고    scopus 로고
    • Phase 2 trial of epothilone B analog BMS-247550 (ixabepilone) in advanced carcinoma of the urothelium (E3800): a trial of the Eastern Cooperative Oncology Group
    • Dreicer R., Li S., Manola J., Haas N.B., Roth B.J., and Wilding G. Phase 2 trial of epothilone B analog BMS-247550 (ixabepilone) in advanced carcinoma of the urothelium (E3800): a trial of the Eastern Cooperative Oncology Group. Cancer 110 (2007) 759-763
    • (2007) Cancer , vol.110 , pp. 759-763
    • Dreicer, R.1    Li, S.2    Manola, J.3    Haas, N.B.4    Roth, B.J.5    Wilding, G.6
  • 88
    • 0027373598 scopus 로고
    • Second line M-VAC therapy in patients previously treated with the M-VAC regimen for metastatic urothelial cancer
    • Kattan J., Culine S., Théodore C., and Droz J.P. Second line M-VAC therapy in patients previously treated with the M-VAC regimen for metastatic urothelial cancer. Ann Oncol 4 9 (1993) 793-794
    • (1993) Ann Oncol , vol.4 , Issue.9 , pp. 793-794
    • Kattan, J.1    Culine, S.2    Théodore, C.3    Droz, J.P.4
  • 89
    • 33746851717 scopus 로고    scopus 로고
    • Phase II study of pemetrexed for second-line treatment of transitional cell cancer of the urothelium
    • Sweeney C.J., Roth B.J., Kabbinavar F.F., et al. Phase II study of pemetrexed for second-line treatment of transitional cell cancer of the urothelium. J Clin Oncol 24 (2006) 3451-3457
    • (2006) J Clin Oncol , vol.24 , pp. 3451-3457
    • Sweeney, C.J.1    Roth, B.J.2    Kabbinavar, F.F.3
  • 90
    • 34248641378 scopus 로고    scopus 로고
    • Phase II trial of pemetrexed as second-line therapy in patients with metastatic urothelial carcinoma
    • Galsky M.D., Mironov S., Iasonos A., Scattergood J., Boyle M.G., and Bajorin D.F. Phase II trial of pemetrexed as second-line therapy in patients with metastatic urothelial carcinoma. Invest New Drugs 25 (2007) 265-270
    • (2007) Invest New Drugs , vol.25 , pp. 265-270
    • Galsky, M.D.1    Mironov, S.2    Iasonos, A.3    Scattergood, J.4    Boyle, M.G.5    Bajorin, D.F.6
  • 91
    • 0035137295 scopus 로고    scopus 로고
    • Post-chemotherapy surgery in patients with unresectable or regionally metastatic bladder cancer
    • Herr H.W., Donat S.M., and Bajorin D.F. Post-chemotherapy surgery in patients with unresectable or regionally metastatic bladder cancer. J Urol Mar 165 3 (2001) 811-814
    • (2001) J Urol Mar , vol.165 , Issue.3 , pp. 811-814
    • Herr, H.W.1    Donat, S.M.2    Bajorin, D.F.3
  • 92
    • 0348109410 scopus 로고    scopus 로고
    • Is there a role for surgery in the management of metastatic urothelial cancer? The M.D. Anderson experience
    • Siefker-Radtke A.O., Walsh G.L., Pisters L.L., et al. Is there a role for surgery in the management of metastatic urothelial cancer? The M.D. Anderson experience. J Urol 171 Jan (1) (2004) 145-148
    • (2004) J Urol , vol.171 , Issue.Jan 1 , pp. 145-148
    • Siefker-Radtke, A.O.1    Walsh, G.L.2    Pisters, L.L.3
  • 93
    • 0027214852 scopus 로고
    • Cisplatin, methotrexate and vinblastine plus surgical restaging for patients with advanced transitional cell carcinoma of the urothelium
    • Miller R.S., Freiha F.S., Reese J.H., Ozen H., and Torti F.M. Cisplatin, methotrexate and vinblastine plus surgical restaging for patients with advanced transitional cell carcinoma of the urothelium. J Urol 150 July (1) (1993) 65-69
    • (1993) J Urol , vol.150 , Issue.July 1 , pp. 65-69
    • Miller, R.S.1    Freiha, F.S.2    Reese, J.H.3    Ozen, H.4    Torti, F.M.5
  • 94
    • 33646844469 scopus 로고    scopus 로고
    • A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen
    • Culine S., Theodore C., De Santis M., et al. A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen. Br J Cancer 94 (2006) 1395-1401
    • (2006) Br J Cancer , vol.94 , pp. 1395-1401
    • Culine, S.1    Theodore, C.2    De Santis, M.3
  • 95
    • 0038354561 scopus 로고    scopus 로고
    • Novel approaches with targeted therapies in bladder cancer. Therapy of bladder cancer by blockade of the epidermal growth factor receptor family
    • Bellmunt J., Hussain M., and Dinney C.P. Novel approaches with targeted therapies in bladder cancer. Therapy of bladder cancer by blockade of the epidermal growth factor receptor family. Crit Rev Oncol Hematol 46 Suppl. (2003) S85-S104
    • (2003) Crit Rev Oncol Hematol , vol.46 , Issue.SUPPL
    • Bellmunt, J.1    Hussain, M.2    Dinney, C.P.3
  • 96
    • 0025906244 scopus 로고
    • Prognostic factors for survival of patients with advanced urothelial tumors treated with methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy
    • Geller N.L., Sternberg C.N., Penenberg D., Scher H., and Yagoda A. Prognostic factors for survival of patients with advanced urothelial tumors treated with methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy. Cancer 67 (1991) 1525-1531
    • (1991) Cancer , vol.67 , pp. 1525-1531
    • Geller, N.L.1    Sternberg, C.N.2    Penenberg, D.3    Scher, H.4    Yagoda, A.5
  • 97
    • 0032887956 scopus 로고    scopus 로고
    • Long-term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy
    • Bajorin D.F., Dodd P.M., Mazumdar M., et al. Long-term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy. J Clin Oncol 17 (1999) 3173-3181
    • (1999) J Clin Oncol , vol.17 , pp. 3173-3181
    • Bajorin, D.F.1    Dodd, P.M.2    Mazumdar, M.3
  • 98
    • 0037103074 scopus 로고    scopus 로고
    • Pretreatment prognostic factors for survival in patients with advanced urothelial tumors treated in a phase I/II trial with paclitaxel, cisplatin, and gemcitabine
    • Bellmunt J., Albanell J., Paz-Ares L., et al. Pretreatment prognostic factors for survival in patients with advanced urothelial tumors treated in a phase I/II trial with paclitaxel, cisplatin, and gemcitabine. Cancer 95 (2002) 751-757
    • (2002) Cancer , vol.95 , pp. 751-757
    • Bellmunt, J.1    Albanell, J.2    Paz-Ares, L.3
  • 99
    • 63749129463 scopus 로고    scopus 로고
    • A nomogram predicting survival or patients with metastatic or unresectable urothelial cancer treated with cisplatin-based chemotherapy
    • [abstr 5055]
    • Bajorin D., Ostrovnaya I., Iasonos A., et al. A nomogram predicting survival or patients with metastatic or unresectable urothelial cancer treated with cisplatin-based chemotherapy. Proc Am Soc Clin Oncol (2007) [abstr 5055]
    • (2007) Proc Am Soc Clin Oncol
    • Bajorin, D.1    Ostrovnaya, I.2    Iasonos, A.3
  • 100
    • 0028061548 scopus 로고
    • P-glycoprotein expression in primary and metastatic transitional cell carcinoma of the bladder
    • Petrylak D.P., Scher H.I., Reuter V., O'Brien J.P., and Cordon-Cardo C. P-glycoprotein expression in primary and metastatic transitional cell carcinoma of the bladder. Ann Oncol 5 (1994) 835-840
    • (1994) Ann Oncol , vol.5 , pp. 835-840
    • Petrylak, D.P.1    Scher, H.I.2    Reuter, V.3    O'Brien, J.P.4    Cordon-Cardo, C.5
  • 101
    • 0030921001 scopus 로고    scopus 로고
    • Translational studies of glutathione in bladder cancer cell lines and human specimens
    • Pendyala L., Velagapudi S., Toth K., et al. Translational studies of glutathione in bladder cancer cell lines and human specimens. Clin Cancer Res 3 (1997) 793-798
    • (1997) Clin Cancer Res , vol.3 , pp. 793-798
    • Pendyala, L.1    Velagapudi, S.2    Toth, K.3
  • 102
    • 0031924088 scopus 로고    scopus 로고
    • The prognostic role of p53, metallothionein, P-glycoprotein, and MIB-1 in muscle-invasive urothelial transitional cell carcinoma
    • Siu L.L., Banerjee D., Khurana R.J., et al. The prognostic role of p53, metallothionein, P-glycoprotein, and MIB-1 in muscle-invasive urothelial transitional cell carcinoma. Clin Cancer Res 4 (1998) 559-565
    • (1998) Clin Cancer Res , vol.4 , pp. 559-565
    • Siu, L.L.1    Banerjee, D.2    Khurana, R.J.3
  • 103
    • 0033780454 scopus 로고    scopus 로고
    • Bcl-2 expression identifies patients with advanced bladder cancer treated by radiotherapy who benefit from neoadjuvant chemotherapy
    • Duggan B., Kelly J., Keane P.F., Williamson K., and Johnston S.R. Bcl-2 expression identifies patients with advanced bladder cancer treated by radiotherapy who benefit from neoadjuvant chemotherapy. BJU Int 86 (2000) 757
    • (2000) BJU Int , vol.86 , pp. 757
    • Duggan, B.1    Kelly, J.2    Keane, P.F.3    Williamson, K.4    Johnston, S.R.5
  • 104
    • 0031882511 scopus 로고    scopus 로고
    • Circumvention of multidrug resistance in genitourinary tumors
    • van Brussel J.P., and Mickisch G.H. Circumvention of multidrug resistance in genitourinary tumors. Int J Urol 5 (1998) 1-15
    • (1998) Int J Urol , vol.5 , pp. 1-15
    • van Brussel, J.P.1    Mickisch, G.H.2
  • 105
    • 0028051625 scopus 로고
    • Accumulation of nuclear p53 and tumor progression in bladder cancer
    • Esrig D., Elmajian D., Groshen S., et al. Accumulation of nuclear p53 and tumor progression in bladder cancer. N Engl J Med 331 (1994) 1259-1264
    • (1994) N Engl J Med , vol.331 , pp. 1259-1264
    • Esrig, D.1    Elmajian, D.2    Groshen, S.3
  • 106
    • 0029063351 scopus 로고
    • Prognostic value of p53 nuclear overexpression in patients with invasive bladder cancer treated with neoadjuvant MVAC
    • Sarkis A.S., Bajorin D.F., Reuter V.E., et al. Prognostic value of p53 nuclear overexpression in patients with invasive bladder cancer treated with neoadjuvant MVAC. J Clin Oncol 13 (1995) 1384-1390
    • (1995) J Clin Oncol , vol.13 , pp. 1384-1390
    • Sarkis, A.S.1    Bajorin, D.F.2    Reuter, V.E.3
  • 107
    • 0036278592 scopus 로고    scopus 로고
    • The prognostic value of angiogenesis and metastasis-related genes for progression of transitional cell carcinoma of the renal pelvis and ureter
    • Inoue K., Kamada M., Slaton J.W., et al. The prognostic value of angiogenesis and metastasis-related genes for progression of transitional cell carcinoma of the renal pelvis and ureter. Clin Cancer Res 8 (2002) 1863-1870
    • (2002) Clin Cancer Res , vol.8 , pp. 1863-1870
    • Inoue, K.1    Kamada, M.2    Slaton, J.W.3
  • 108
    • 34547670602 scopus 로고    scopus 로고
    • Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer
    • Als A.B., Dyrskjot L., von der Maase H., et al. Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer. Clin Cancer Res 13 (2007) 4407-4414
    • (2007) Clin Cancer Res , vol.13 , pp. 4407-4414
    • Als, A.B.1    Dyrskjot, L.2    von der Maase, H.3
  • 109
    • 84920241849 scopus 로고
    • Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumours
    • Neal D.E., Marsh C., Bennett M.K., et al. Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumours. Lancet 1 (1985) 366-368
    • (1985) Lancet , vol.1 , pp. 366-368
    • Neal, D.E.1    Marsh, C.2    Bennett, M.K.3
  • 110
    • 0037386689 scopus 로고    scopus 로고
    • The need to embrace molecular profiling of tumor cells in prostate and bladder cancer
    • Duggan B.J., McKnight J.J., Williamson K.E., et al. The need to embrace molecular profiling of tumor cells in prostate and bladder cancer. Clin Cancer Res 9 (2003) 1240-1247
    • (2003) Clin Cancer Res , vol.9 , pp. 1240-1247
    • Duggan, B.J.1    McKnight, J.J.2    Williamson, K.E.3
  • 111
    • 0036897242 scopus 로고    scopus 로고
    • Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes
    • Sanchez-Carbayo M., Socci N.D., Charytonowicz E., et al. Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes. Cancer Res 62 (2002) 6973-6980
    • (2002) Cancer Res , vol.62 , pp. 6973-6980
    • Sanchez-Carbayo, M.1    Socci, N.D.2    Charytonowicz, E.3
  • 112
    • 0037224449 scopus 로고    scopus 로고
    • Identifying distinct classes of bladder carcinoma using microarrays
    • Dyrskjot L., Thykjaer T., Kruhoffer M., et al. Identifying distinct classes of bladder carcinoma using microarrays. Nat Genet 33 (2003) 90-96
    • (2003) Nat Genet , vol.33 , pp. 90-96
    • Dyrskjot, L.1    Thykjaer, T.2    Kruhoffer, M.3
  • 113
    • 0037028745 scopus 로고    scopus 로고
    • Allelic imbalances in human bladder cancer: genome-wide detection with high-density single-nucleotide polymorphism arrays
    • Primdahl H., Wikman F.P., von der Maase H., Zhou X.G., Wolf H., and Orntoft T.F. Allelic imbalances in human bladder cancer: genome-wide detection with high-density single-nucleotide polymorphism arrays. J Natl Cancer Inst 94 (2002) 216-223
    • (2002) J Natl Cancer Inst , vol.94 , pp. 216-223
    • Primdahl, H.1    Wikman, F.P.2    von der Maase, H.3    Zhou, X.G.4    Wolf, H.5    Orntoft, T.F.6
  • 114
    • 0035866788 scopus 로고    scopus 로고
    • Identification of gene expression patterns in superficial and invasive human bladder cancer
    • Thykjaer T., Workman C., Kruhoffer M., et al. Identification of gene expression patterns in superficial and invasive human bladder cancer. Cancer Res 61 (2001) 2492-2499
    • (2001) Cancer Res , vol.61 , pp. 2492-2499
    • Thykjaer, T.1    Workman, C.2    Kruhoffer, M.3
  • 115
    • 17444438042 scopus 로고    scopus 로고
    • Applications of array technology: identification of molecular targets in bladder cancer
    • Sanchez-Carbayo M., and Cordon-Cardo C. Applications of array technology: identification of molecular targets in bladder cancer. Br J Cancer 89 (2003) 2172-2177
    • (2003) Br J Cancer , vol.89 , pp. 2172-2177
    • Sanchez-Carbayo, M.1    Cordon-Cardo, C.2
  • 116
    • 33644867290 scopus 로고    scopus 로고
    • Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays
    • Sanchez-Carbayo M., Socci N.D., Lozano J., Saint F., and Cordon-Cardo C. Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays. J Clin Oncol 24 (2006) 778-789
    • (2006) J Clin Oncol , vol.24 , pp. 778-789
    • Sanchez-Carbayo, M.1    Socci, N.D.2    Lozano, J.3    Saint, F.4    Cordon-Cardo, C.5
  • 117
    • 0037445965 scopus 로고    scopus 로고
    • Molecular targeting and pharmacogenomics in the management of advanced bladder cancer
    • Raghavan D. Molecular targeting and pharmacogenomics in the management of advanced bladder cancer. Cancer 97 (2003) 2083-2089
    • (2003) Cancer , vol.97 , pp. 2083-2089
    • Raghavan, D.1
  • 119
    • 10744224719 scopus 로고    scopus 로고
    • Molecular predictors of response to chemotherapy in lung cancer
    • Rosell R., Taron M., Ariza A., et al. Molecular predictors of response to chemotherapy in lung cancer. Semin Oncol 31 (2004) 20-27
    • (2004) Semin Oncol , vol.31 , pp. 20-27
    • Rosell, R.1    Taron, M.2    Ariza, A.3
  • 120
    • 0037444279 scopus 로고    scopus 로고
    • Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines
    • Selvakumaran M., Pisarcik D.A., Bao R., Yeung A.T., and Hamilton T.C. Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines. Cancer Res 63 (2003) 1311-1316
    • (2003) Cancer Res , vol.63 , pp. 1311-1316
    • Selvakumaran, M.1    Pisarcik, D.A.2    Bao, R.3    Yeung, A.T.4    Hamilton, T.C.5
  • 121
    • 0027472693 scopus 로고
    • Expression of excision repair genes in non-malignant bone marrow from cancer patients
    • Dabholkar M., Bostick-Bruton F., Weber C., Egwuagu C., Bohr V.A., and Reed E. Expression of excision repair genes in non-malignant bone marrow from cancer patients. Mutat Res 293 (1993) 151-160
    • (1993) Mutat Res , vol.293 , pp. 151-160
    • Dabholkar, M.1    Bostick-Bruton, F.2    Weber, C.3    Egwuagu, C.4    Bohr, V.A.5    Reed, E.6
  • 122
    • 0033797293 scopus 로고    scopus 로고
    • ERCC1 expression as a molecular marker of cisplatin resistance in human cervical tumor cells
    • Britten R.A., Liu D., Tessier A., Hutchison M.J., and Murray D. ERCC1 expression as a molecular marker of cisplatin resistance in human cervical tumor cells. Int J Cancer 89 (2000) 453-457
    • (2000) Int J Cancer , vol.89 , pp. 453-457
    • Britten, R.A.1    Liu, D.2    Tessier, A.3    Hutchison, M.J.4    Murray, D.5
  • 123
    • 0028141961 scopus 로고
    • Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy
    • Dabholkar M., Vionnet J., Bostick-Bruton F., Yu J.J., and Reed E. Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy. J Clin Invest 94 (1994) 703-708
    • (1994) J Clin Invest , vol.94 , pp. 703-708
    • Dabholkar, M.1    Vionnet, J.2    Bostick-Bruton, F.3    Yu, J.J.4    Reed, E.5
  • 124
    • 0031982522 scopus 로고    scopus 로고
    • ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy
    • Metzger R., Leichman C.G., Danenberg K.D., et al. ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J Clin Oncol 16 (1998) 309-316
    • (1998) J Clin Oncol , vol.16 , pp. 309-316
    • Metzger, R.1    Leichman, C.G.2    Danenberg, K.D.3
  • 125
    • 0035576102 scopus 로고    scopus 로고
    • ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy
    • Shirota Y., Stoehlmacher J., Brabender J., et al. ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy. J Clin Oncol 19 (2001) 4298-4304
    • (2001) J Clin Oncol , vol.19 , pp. 4298-4304
    • Shirota, Y.1    Stoehlmacher, J.2    Brabender, J.3
  • 126
    • 33847681504 scopus 로고    scopus 로고
    • Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy
    • Bellmunt J., Paz-Ares L., Cuello M., et al. Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy. Ann Oncol 18 (2007) 522-528
    • (2007) Ann Oncol , vol.18 , pp. 522-528
    • Bellmunt, J.1    Paz-Ares, L.2    Cuello, M.3
  • 127
    • 0030951820 scopus 로고    scopus 로고
    • Evaluation of epidermal growth factor receptor, transforming growth factor alpha, epidermal growth factor and c-erbB2 in the progression of invasive bladder cancer
    • Ravery V., Grignon D., Angulo J., et al. Evaluation of epidermal growth factor receptor, transforming growth factor alpha, epidermal growth factor and c-erbB2 in the progression of invasive bladder cancer. Urol Res 25 (1997) 9-17
    • (1997) Urol Res , vol.25 , pp. 9-17
    • Ravery, V.1    Grignon, D.2    Angulo, J.3
  • 128
    • 0035220223 scopus 로고    scopus 로고
    • Differential expression of progression-related genes in the evolution of superficial to invasive transitional cell carcinoma of the bladder
    • Izawa J.I., Slaton J.W., Kedar D., et al. Differential expression of progression-related genes in the evolution of superficial to invasive transitional cell carcinoma of the bladder. Oncol Rep 8 (2001) 9-15
    • (2001) Oncol Rep , vol.8 , pp. 9-15
    • Izawa, J.I.1    Slaton, J.W.2    Kedar, D.3
  • 129
    • 0000583326 scopus 로고    scopus 로고
    • Monoclonal antibody IMC-C225, an anti-epidermal growth factor receptor, for patients with EGFr-positive tumors refractory to or in relapse from previous therapeutic regimens
    • [abstr 474]
    • Rubin M., Shin D., Pasmatier M., et al. Monoclonal antibody IMC-C225, an anti-epidermal growth factor receptor, for patients with EGFr-positive tumors refractory to or in relapse from previous therapeutic regimens. Proc Am Soc Clin Oncol (2000) [abstr 474]
    • (2000) Proc Am Soc Clin Oncol
    • Rubin, M.1    Shin, D.2    Pasmatier, M.3
  • 130
    • 36849022660 scopus 로고    scopus 로고
    • A phase II trial of cisplatin, fixed dose-rate gemcitabine and gefitinib for advanced urothelial tract carcinoma: results of the Cancer and Leukaemia Group B 90102
    • Philips G.K., Halabi S., Sanford B.L., Bajorin D., and Small E.J. A phase II trial of cisplatin, fixed dose-rate gemcitabine and gefitinib for advanced urothelial tract carcinoma: results of the Cancer and Leukaemia Group B 90102. BJU Int 101 (2008) 20-25
    • (2008) BJU Int , vol.101 , pp. 20-25
    • Philips, G.K.1    Halabi, S.2    Sanford, B.L.3    Bajorin, D.4    Small, E.J.5
  • 131
    • 34250218955 scopus 로고    scopus 로고
    • Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: results of a multicenter phase II National Cancer Institute trial
    • Hussain M.H., MacVicar G.R., Petrylak D.P., et al. Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: results of a multicenter phase II National Cancer Institute trial. J Clin Oncol 25 (2007) 2218-2224
    • (2007) J Clin Oncol , vol.25 , pp. 2218-2224
    • Hussain, M.H.1    MacVicar, G.R.2    Petrylak, D.P.3
  • 132
    • 63749092659 scopus 로고    scopus 로고
    • Trastuzumab combined with standard chemotherapy in HER + metastatic bladder cancer patients: interim safety results of a prospective randomized phase II study
    • [abstr 15565]
    • Beuzeboc P., Banu E., Voog E., et al. Trastuzumab combined with standard chemotherapy in HER + metastatic bladder cancer patients: interim safety results of a prospective randomized phase II study. Proc Am Soc Clin Oncol (2007) [abstr 15565]
    • (2007) Proc Am Soc Clin Oncol
    • Beuzeboc, P.1    Banu, E.2    Voog, E.3
  • 133
    • 29844435981 scopus 로고    scopus 로고
    • A single arm, multicenter, open label, ph II study of lapatinib as 2L treatment of pts with locally advanced/metastatic transitional cell carcinoma (TCC) of the urothelial tract
    • [abstr 4594]
    • Wülfing C., Machiels J., Richel D., et al. A single arm, multicenter, open label, ph II study of lapatinib as 2L treatment of pts with locally advanced/metastatic transitional cell carcinoma (TCC) of the urothelial tract. Proc Am Soc Clin Oncol (2005) [abstr 4594]
    • (2005) Proc Am Soc Clin Oncol
    • Wülfing, C.1    Machiels, J.2    Richel, D.3
  • 134
    • 63749125047 scopus 로고    scopus 로고
    • Sunitinib malate is active and synergistic with cisplatin against human urothelial carcinoma in a preclinical model
    • [abstr 15632]
    • Sonpavde G., Jian W., and Lerner S. Sunitinib malate is active and synergistic with cisplatin against human urothelial carcinoma in a preclinical model. Proc Am Soc Clin Oncol (2007) [abstr 15632]
    • (2007) Proc Am Soc Clin Oncol
    • Sonpavde, G.1    Jian, W.2    Lerner, S.3
  • 135
    • 36749078435 scopus 로고    scopus 로고
    • Phase II study of sunitinib in patients with relapsed or refractory urothelial
    • [abstr 5080]
    • Gallagher D., Milowsky M., Gerst S., et al. Phase II study of sunitinib in patients with relapsed or refractory urothelial. Proc Am Soc Clin Oncol (2007) [abstr 5080]
    • (2007) Proc Am Soc Clin Oncol
    • Gallagher, D.1    Milowsky, M.2    Gerst, S.3


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