Bioconjugation and detection of lactosamine moiety using αl, 3-galactosyltransferase mutants that transfer C2-modified galactose with a chemical handle

Bioconjugate Chemistry

Volumn 20, Issue 3, 2009, Pages 608-618

  Pasek, Marta ^a   Ramakrishnan, Boopathy ^a   Boeggeman, Elizabeth ^a   Manzoni, Maria ^a   Waybright, Timothy J ^a   Qasba, Pradman K ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ALPHA 1,3 GALACTOSYLTRANSFERASE; ASIALOFETUIN; AZIDE; CARBOHYDRATE BINDING PROTEIN; GALACTOSE; GLYCAN DERIVATIVE; GLYCINE; HISTIDINE; LACTOSAMINE; LEUCINE; MUTANT PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; AMINOSUGAR; GALACTOSYLTRANSFERASE; N-ACETYLLACTOSAMINE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOHYDRATE ANALYSIS; CHEMOLUMINESCENCE; CONJUGATION; ENZYME ACTIVITY; ENZYME STRUCTURE; INDUCED MUTATION; NONHUMAN; SITE DIRECTED MUTAGENESIS; SUGAR TRANSPORT; WILD TYPE; ANIMAL; BOVINAE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; SEQUENCE ALIGNMENT;

BOVINAE;

AMINO ACID SEQUENCE; AMINO SUGARS; ANIMALS; BASE SEQUENCE; CATTLE; GALACTOSE; GALACTOSYLTRANSFERASES; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ALIGNMENT;

EID: 63749108116     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc800534r     Document Type: Article

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