Antidepressant-associated myoclonic status in a patient with symptomatic generalized epilepsy: Does risk occur with therapeutic doses?

Epilepsy and Behavior

Volumn 14, Issue 4, 2009, Pages 681-683

  Melani, Federico ^a   Rosati, Eleonora ^a   Chiocchetti, Barbara ^a   Muscas, Gian Carlo ^a  

^a CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

Electroencephalogram; Myoclonus; Selective serotonin reuptake inhibitors; Serotonin noradrenaline reuptake inhibitors; Spike wave discharges

Indexed keywords

CLONAZEPAM; DULOXETINE; ETHOSUXIMIDE; PAROXETINE; TOPIRAMATE; VALPROIC ACID;

ADULT; AGITATION; ANOREXIA; ARTICLE; CASE REPORT; CLINICAL FEATURE; DEPRESSION; DIAPHORESIS; DRUG BLOOD LEVEL; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSARTHRIA; ELECTROENCEPHALOGRAM; ENCEPHALITIS; EPILEPSY; FECES INCONTINENCE; GENERALIZED EPILEPSY; HUMAN; MALE; MENTAL DEFICIENCY; MYOCLONUS SEIZURE; NUCLEAR MAGNETIC RESONANCE IMAGING; SHIVERING; SIDE EFFECT; SPEECH DISORDER; TONIC CLONIC SEIZURE; TREMOR; URINE INCONTINENCE; WEIGHT GAIN;

ANTIDEPRESSIVE AGENTS; DEPRESSION; ELECTROENCEPHALOGRAPHY; EPILEPSY, GENERALIZED; HUMANS; MALE; MIDDLE AGED; PAROXETINE; SEIZURES; THIOPHENES;

EID: 63749101129     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2009.01.018     Document Type: Article

References (14)

1. Lee KC, Finley PR, Alldredge BK. Risk of seizures associated with psychotropic medications: emphasis on new drugs and new findings. Expert Opin Drug Saf 2003;2:233-247.
2. Montgomery S.A. Antidepressants and seizures: emphasis on newer agents and clinical implications. Int J Clin Pract 59 (2005) 1435-1440
3. Maramattom B.V. Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion and seizures. Neurology 66 (2006) 773-774
4. Specchio L.M., Iudice A., Specchio N., et al. Citalopram as treatment of depression in patients with epilepsy. Clin Neuropharmacol 27 (2004) 133-136
5. Kanner A.M., Kozak A.M., and Frey M. The use of sertraline in patients with epilepsy: is it safe?. Epilepsy Behav 1 (2000) 100-105
6. Cymbalta, European Public Assessment Report, Scientific Discussion.
7. Perrucca E., Gram L., Avanzini G., and Dulac O. Antiepileptic drugs as a cause of worsening seizures. Epilepsia 39 (1998) 5-17
8. Gayatri N.A., and Livingstone J.H. Aggravation of epilepsy by anti-epileptic drugs. Dev Med Child Neurol 48 (2006) 394-398
9. Guerrini R., Dravet C., Genton P., Belmonte A., Kaminska A., and Dulac O. Lamotrigine and seizure aggravation in severe myoclonic epilepsy. Epilepsia 39 (1998) 508-512
10. Kaddurah A.K., and Holmes G.L. Possible precipitation of myoclonic seizures with oxcarbazepine. Epilepsy Behav 8 (2006) 289-293
11. Sternbach H. The serotonin syndrome. Am J Psychiatry 148 (1991) 705-713
12. Welsh J.P., Placantonakis D.G., Warsetsky S.I., et al. The serotonin hypothesis of myoclonus from the perspective of neuronal rhythmicity. Adv Neurol 89 (2002) 307-329
13. Meschaks A., Lindstrom P., Halldin C., Farde L., and Savic I. Regional reductions in serotonin 1A receptor binding in juvenile myoclonic epilepsy. Arch Neurol 62 (2005) 946-950
14. Bagdy G., Kecskemeti V., Riba P., and Jakus R. Serotonin and epilepsy. Neurochemistry 100 (2007) 857-873