Walking track analysis: An assessment method for functional recovery after sciatic nerve injury in the rat

Folia Morphologica

Volumn 68, Issue 1, 2009, Pages 1-7

  Sarikcioglu, L ^a   Demirel, B M ^a   Utuk, A ^a  

^a AKDENIZ UNIVERSITY FACULTY OF MEDICINE   (Turkey)

Author keywords

Intermediate toe spread; Print length; Sciatic function index; Toe spread; Walking track analysis

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOTOMY; CONTRACTURE; CONTROLLED STUDY; FUNCTIONAL ASSESSMENT; GAIT; MOTOR NERVE; NERVE FUNCTION; NERVE INJURY; NERVE REGENERATION; NEUROSCIENCE; NONHUMAN; RAT; REVIEW; SCIATIC NERVE; WALKING;

ANIMALS; DISEASE MODELS, ANIMAL; GAIT; GAIT DISORDERS, NEUROLOGIC; NERVE REGENERATION; RATS; RECOVERY OF FUNCTION; SCIATIC NERVE; SCIATIC NEUROPATHY;

RATTUS;

EID: 63749097753     PISSN: 00155659     EISSN: 16443284     Source Type: Journal    
DOI: None     Document Type: Review

References (43)

1. Bain JR, Mackinnon SE, Hunter DA (1989) Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat. Plast Reconstr Surg, 83: 129-138.
2. Banos JE, Verclu E, Buti M, Navarro X (1994) Effects of dizocilpine on autotomy behavior after nerve section in mice. Brain Res, 636: 107-110.
3. Berenberg RA, Forman DS, Wood DK, DeSilva A, Demaree J (1977) Recovery of peripheral nerve function after axotomy: effect of triiodothyronine. Exp Neurol, 57: 349-363.
4. Bervar M (2000) Video analysis of standing - an alternative footprint analysis to assess functional loss following injury to the rat sciatic nerve. J Neurosci Methods, 102: 109-116.
5. Carlton JM, Goldberg NH (1986) Quantitating integrated muscle function following reinnervation. Surg Forum, 37: 611-614.
6. Carr MM, Best TJ, Mackinnon SE, Evans PJ (1992) Strain differences in autotomy in rats undergoing sciatic nerve transection or repair. Ann Plast Surg, 28: 538-544.
7. Chamberlain U, Yannas IV, Hsu HP, Strichartz GR, Spector M (2000) Near-terminus axonal structure and function following rat sciatic nerve regeneration through a collagen-GAG matrix in a ten-millimeter gap. J Neurosci Res, 60: 666-677.
8. Coderre TJ, Grimes RW, Melzack R (1986) Autotomy following sciatic and saphenous nerve sections: sparing of the medial toes after treatment of the sciatic nerve with capsaicin. Exp Neurol, 91: 355-365.
9. De Koning P, Gispen WH (1987) Org.2766 improves functional and electrophysiological aspects of regenerating sciatic nerve in the rat. Peptides, 8: 415-422.
10. de Medinaceli L, Freed WJ, Wyatt RJ (1982) An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks. Exp Neurol, 77: 634-643.
11. Dellon AL, Mackinnon SE (1989) Selection of the appropriate parameter to measure neural regeneration. Ann Plast Surg, 23: 197-202.
12. Dellon ES, Dellon AL (1991) Functional assessment of neurologic impairment: track analysis in diabetic and compression neuropathies. Plast Reconstr Surg, 88: 686-694.
13. Dijkstra JR, Meek MF, Robinson PH, Gramsbergen A (2000) Methods to evaluate functional nerve recovery in adult rats: walking track analysis, video analysis and the withdrawal reflex. J Neurosci Methods, 96: 89-96.
14. Gramsbergen A, J IJ-P, Meek MF (2000) Sciatic nerve transection in the adult rat: abnormal EMG patterns during locomotion by aberrant innervation of hindleg muscles. Exp Neurol, 161: 183-193.
15. Gutmann E (1942) Factors affecting recovery of motor function after nerve lesions. J Neurol Phychiatr, 5: 81-95.
16. Hadlock TA, Koka R, Vacanti JP, Cheney ML (1999) A comparison of assessments of functional recovery in the rat. J Peripher Nerv Syst, 4: 258-264.
17. Hare GM, Evans PJ, Mackinnon SE, Best TJ, Bain JR, Szalai JP, Hunter DA (1992) Walking track analysis: a long-term assessment of peripheral nerve recovery. Plast Reconstr Surg, 89: 251-258.
18. Hasegawa K (1978) A new method of measuring functional recovery after crushing the peripheral nerves in unanesthetized and unrestrained rats. Experientia, 34: 272-273.
19. Hruska RE, Kennedy S, Silbergeld EK (1979) Quantitative aspects of normal locomotion in rats. Life Sci, 25: 171-179.
20. Hruska RE, Silbergeld EK (1979) Abnormal locomotion in rats after bilateral injection of kainic acid. Life Sci, 25: 181-194.
21. Inserra MM, Bloch DA, Terris DJ (1998) Functional indices for sciatic, peroneal, and posterior tibial nerve lesions in the mouse. Microsurgery, 18: 119-124.
22. Johnston RB, Zachary L, Dellon AL, Seiler WAt, Teplica DM (1991) Improved imaging of rat hindfoot prints for walking track analysis. J Neurosci Methods, 38: 111-114.
23. Kanaya F, Firrell JC, Breidenbach WC (1996) Sciatic function index, nerve conduction tests, muscle contraction, and axon morphometry as indicators of regeneration. Plast Reconstr Surg, 98: 1264-1271 (discussion 1272-1264).
24. Kingery WS, Castellote JM, Maze M (1999) Methylprednisolone prevents the development of autotomy and neuropathic edema in rats, but has no effect on nociceptive thresholds. Pain, 80: 555-566.
25. Kobayashi J, Mackinnon SE, Watanabe O, Ball DJ, Gu XM, Hunter DA, Kuzon WM, Jr. (1997) The effect of duration of muscle denervation on functional recovery in the rat model. Muscle Nerve, 20: 858-866.
26. Lin FM, Pan YC, Hom C, Sabbahi M, Shenaq S (1996) Ankle stance angle: a functional index for the evaluation of sciatic nerve recovery after complete transection. J Reconstr Microsurg, 12: 173-177.
27. Lowdon IM, Seaber AV, Urbaniak JR (1988) An improved method of recording rat tracks for measurement of the sciatic functional index of cle Medinaceli. J Neurosci Methods, 24: 279-281.
28. Mackinnon SE, Dellon AL, O'Brien JP (1991) Changes in nerve fiber numbers distal to a nerve repair in the rat sciatic nerve model. Muscle Nerve, 14: 1116-1122.
29. Mackinnon SE, Hudson AR, Hunter DA (1985) Histologic assessment of nerve regeneration in the rat. Plast Reconstr Surg, 75: 384-388.
30. Munro CA, Szalai JP, Mackinnon SE, Midha R (1998) Lack of association between outcome measures of nerve regeneration. Muscle Nerve, 21: 1095-1097.
31. Rappaport ZH, Seltzer Z, Zagzag D (1986) The effect of glycerol on autotomy. An experimental model of neuralgia pain. Pain, 26: 85-91.
32. Rushton R, Steinberg H, Tinson C (1963) The effects of a single experience on subsequent reactions to drugs. Br J Pharmacol, 29: 99-102.
33. Sarikcioglu L, Oguz N (2001) Exercise training and axonal regeneration after sciatic nerve injury. Int J Neurosci, 109: 173-177.
34. Sporel-Ozakat RE, Edwards PM, Hepgul KT, Savas A, Gispen WH (1991) A simple method for reducing autotomy in rats after peripheral nerve lesions. J Neurosci Methods, 36: 263-265.
35. Urbanchek MS, Chung KC, Asato H, Washington LN, Kuzon WM, Jr. (1999) Rat walking tracks do not reflect maximal muscle force capacity. J Reconstr Microsurg, 15: 143-149.
36. van Meeteren NL, Brakkee JH, Hamers FP, Helders PJ, Gispen WH (1997) Exercise training improves functional recovery and motor nerve conduction velocity after sciatic nerve crush lesion in the rat. Arch Phys Med Rehabil, 78: 70-77.
37. Varejao AS, Meek MF, Ferreira AJ, Patricio JA, Cabrita AM (2001) Functional evaluation of peripheral nerve regeneration in the rat: walking track analysis. J Neurosci Methods, 108: 1-9.
38. Walker JL, Evans JM, Meade P, Resig P, Sisken BF (1994) Gait-stance duration as a measure of injury and recovery in the rat sciatic nerve model. J Neurosci Methods, 52: 47-52.
39. Wall PD, Devor M, I nbal R, Scadding JW, Schonfeld D, Seltzer Z, Tomkiewicz MM (1979) Autotomy following peripheral nerve lesions: experimental anaesthesia dolorosa. Pain, 7: 103-111.
40. Weber RA, Proctor WH, Warner MR, Verheyden CN (1993) Autotomy and the sciatic functional index. Microsurgery, 14: 323-327.
41. Westerga J, Gramsbergen A (1990) The development of locomotion in the rat. Brain Res Dev Brain Res, 57: 163-174.
42. Yao M, Inserra MM, Duh MJ, Terris DJ (1998) A longitudinal, functional study of peripheral nerve recovery in the mouse. Laryngoscope, 108: 1141-1145.
43. Zellem RT, Miller DW, Kenning JA, Hoenig EM, Buchheit WA (1989) Experimental peripheral nerve repair: environmental control directed at the cellular level. Microsurgery, 10: 290-301.