Update on pediatric pheochromocytoma

Pediatric Nephrology

Volumn 24, Issue 5, 2009, Pages 943-950

  Havekes, Bas ^a,b   Romijn, Johannes A ^b   Eisenhofer, Graeme ^c   Adams, Karen ^a   Pacak, Karel ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Catecholamines; Children; Genetics; Imaging; Metanephrines; Paraganglioma; Pheochromocytoma; Positron emission tomography (PET)

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 123; ADRENALIN; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CATECHOLAMINE; DOPAMINE; METADRENALIN; NORADRENALIN; NORMETADRENALIN; PHENOXYBENZAMINE; PROTEIN RET; SUCCINATE DEHYDROGENASE; VANILMANDELIC ACID;

ADRENAL MEDULLECTOMY; BLOOD CHEMISTRY; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DISEASE CARRIER; GENE MUTATION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; HUMAN; HYPERTENSION; HYPOTENSION; MULTIPLE ENDOCRINE NEOPLASIA; NEUROFIBROMATOSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PHEOCHROMOCYTOMA; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; REVIEW; SENSITIVITY AND SPECIFICITY; TUMOR LOCALIZATION; URINALYSIS; VON HIPPEL LINDAU DISEASE;

ADRENAL GLAND NEOPLASMS; CHILD; FEMALE; HUMANS; MALE; METANEPHRINE; PHEOCHROMOCYTOMA; PREDICTIVE VALUE OF TESTS;

EID: 63649161402     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-008-0888-9     Document Type: Review

References (66)

1. Pacak K, Eisenhofer G, Ahlman H, Bornstein SR, Gimenez-Roqueplo AP, Grossman AB, Kimura N, Mannelli M, McNicol AM, Tischler AS (2007) Pheochromocytoma: Recommendations for clinical practice from the First International Symposium. October 2005. Nat Clin Pract Endocrinol Metab 3:92-102
2. Stringel G, Ein SH, Creighton R, Daneman D, Howard N, Filler RM (1980) Pheochromocytoma in children-an update. J Pediatr Surg 15:496-500
3. Ein SH, Shandling B, Wesson D, Filler R (1990) Recurrent pheochromocytomas in children. J Pediatr Surg 25:1063-1065
4. Pham TH, Moir C, Thompson GB, Zarroug AE, Hamner CE, Farley D, Van HJ, Lteif AN, Young WF Jr (2006) Pheochromocytoma and paraganglioma in children: A review of medical and surgical management at a tertiary care center. Pediatrics 118:1109-1117
5. Weise M, Merke DP, Pacak K, Walther MM, Eisenhofer G (2002) Utility of plasma free metanephrines for detecting childhood pheochromocytoma. J Clin Endocrinol Metab 87:1955-1960
6. Lenders JW, Eisenhofer G, Mannelli M, Pacak K (2005) Phaeochromocytoma. Lancet 366:665-675
7. de Krijger RR, Petri BJ, van Nederveen FH, Korpershoek E, de Herder WW, De Muinck Keizer-Schrama SM, Dinjens WN (2006) Frequent genetic changes in childhood pheochromocytomas. Ann NY Acad Sci 1073:166-176
8. Perel Y, Schlumberger M, Marguerite G, Alos N, Revillon Y, Sommelet D, De Lumley L, Flamant F, Dyon JF, Lutz P, Heloury H, Lemerle J (1997) Pheochromocytoma and paraganglioma in children: A report of 24 cases of the French Society of Pediatric Oncology. Pediatr Hematol Oncol 14:413-422
9. Whalen RK, Althausen AF, Daniels GH (1992) Extra-adrenal pheochromocytoma. J Urol 147:1-10
10. Ciftci AO, Tanyel FC, Senocak ME, Buyukpamukcu N (2001) Pheochromocytoma in children. J Pediatr Surg 36:447-452
11. Barontini M, Levin G, Sanso G (2006) Characteristics of pheochromocytoma in a 4- to 20-year-old population. Ann NY Acad Sci 1073:30-37
12. Caty MG, Coran AG, Geagen M, Thompson NW (1990) Current diagnosis and treatment of pheochromocytoma in children. Experience with 22 consecutive tumors in 14 patients. Arch Surg 125:978-981
13. Ross JH (2000) Pheochromocytoma. Special considerations in children. Urol Clin North Am 27:393-402
14. Baysal BE (2003) On the association of succinate dehydrogenase mutations with hereditary paraganglioma. Trends Endocrinol Metab 14:453-459
15. Benn DE, Gimenez-Roqueplo AP, Reilly JR, Bertherat J, Burgess J, Byth K, Croxson M, Dahia PL, Elston M, Gimm O, Henley D, Herman P, Murday V, Niccoli-Sire P, Pasieka JL, Rohmer V, Tucker K, Jeunemaitre X, Marsh DJ, Plouin PF, Robinson BG (2006) Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes. J Clin Endocrinol Metab 91:827-836
16. Neumann HP, Pawlu C, Peczkowska M, Bausch B, McWhinney SR, Muresan M, Buchta M, Franke G, Klisch J, Bley TA, Hoegerle S, Boedeker CC, Opocher G, Schipper J, Januszewicz A, Eng C (2004) Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. JAMA 292:943-951
17. Timmers HJ, Kozupa A, Eisenhofer G, Raygada M, Adams KT, Solis D, Lenders JW, Pacak K (2007) Clinical presentations, biochemical phenotypes, and genotype-phenotype correlations in patients with succinate dehydrogenase subunit B-associated pheochromocytomas and paragangliomas. J Clin Endocrinol Metab 92:779-786
18. Amar L, Bertherat J, Baudin E, Ajzenberg C, Bressac-de Paillerets B, Chabre O, Chamontin B, Delemer B, Giraud S, Murat A, Niccoli-Sire P, Richard S, Rohmer V, Sadoul JL, Strompf L, Schlumberger M, Bertagna X, Plouin PF, Jeunemaitre X, Gimenez-Roqueplo AP (2005) Genetic testing in pheochromocytoma or functional paraganglioma. J Clin Oncol 23:8812-8818
19. Beltsevich DG, Kuznetsov NS, Kazaryan AM, Lysenko MA (2004) Pheochromocytoma surgery: Epidemiologic peculiarities in children. World J Surg 28:592-596
20. Varda NM, Gregoric A (2005) A diagnostic approach for the child with hypertension. Pediatr Nephrol 20:499-506
21. Ludwig AD, Feig DI, Brandt ML, Hicks MJ, Fitch ME, Cass DL (2007) Recent advances in the diagnosis and treatment of pheochromocytoma in children. Am J Surg 194:792-796
22. Zelinka T, Strauch B, Petrak O, Holaj R, Vrankova A, Weisserova H, Pacak K, Widimsky J Jr (2005) Increased blood pressure variability in pheochromocytoma compared to essential hypertension patients. J Hypertens 23:2033-2039
23. Zelinka T, Pacak K, Widimsky J Jr (2006) Characteristics of blood pressure in pheochromocytoma. Ann NY Acad Sci 1073:86-93
24. Grondal S, Hamberger B, Telenius-Berg M (1986) Secretory pattern and blood pressure in pheochromocytoma. World J Surg 10:724-728
25. Bravo EL, Tagle R (2003) Pheochromocytoma: State-of-the-art and future prospects. Endocr Rev 24:539-553
26. Bergland BE (1989) Pheochromocytoma presenting as shock. Am J Emerg Med 7:44-48
27. Proye C, Fossati P, Fontaine P, Lefebvre J, Decoulx M, Wemeau JL, Dewailly D, Rwamasirabo E, Cecat P (1986) Dopamine-secreting pheochromocytoma: An unrecognized entity? Classification of pheochromocytomas according to their type of secretion. Surgery 100:1154-1162
28. Pacak K, Lenders JW, Eisenhofer G (2007) Pheochromocytoma; diagnosis, localization and treatment. Blackwell Publishing Ltd, Oxford, p 11
29. Hack HA (2000) The perioperative management of children with phaeochromocytoma. Paediatr Anaesth 10:463-476
30. Haws R, Joseph M, Adelman R (2007) Two cases of pheochromocytoma presenting with ADHD (attention deficit hyperactivity disorder)-like symptoms. Pediatr Nephrol 23:473-475
31. La Batide-Alanore A, Chatellier G, Plouin PF (2003) Diabetes as a marker of pheochromocytoma in hypertensive patients. J Hypertens 21:1703-1707
32. van Lennep JR, Romijn JA, Harinck HI (2007) Multi-organ failure after a glucagon test. Lancet 369:798
33. van der Mey AG, Maaswinkel-Mooy PD, Cornelisse CJ, Schmidt PH, van de Kamp JJ (1989) Genomic imprinting in hereditary glomus tumours: Evidence for new genetic theory. Lancet 2:1291-1294
34. van Houtum WH, Corssmit EP, Douwes Dekker PB, Jansen JC, van der Mey AG, Brocker-Vriends AH, Taschner PE, Losekoot M, Frolich M, Stokkel MP, Cornelisse CJ, Romijn JA (2005) Increased prevalence of catecholamine excess and phaeochromocytomas in a well-defined Dutch population with SDHD-linked head and neck paragangliomas. Eur J Endocrinol 152:87-94
35. Havekes B, Corssmit EP, Jansen JC, van der Mey AG, Vriends AH, Romijn JA (2007) Malignant paragangliomas associated with mutations in the succinate dehydrogenase D gene. J Clin Endocrinol Metab 92:1245-1248
36. Astuti D, Latif F, Dallol A, Dahia PL, Douglas F, George E, Skoldberg F, Husebye ES, Eng C, Maher ER (2001) Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. Am J Hum Genet 69:49-54
37. Eisenhofer G, Walther MM, Huynh TT, Li ST, Bornstein SR, Vortmeyer A, Mannelli M, Goldstein DS, Linehan WM, Lenders JW, Pacak K (2001) Pheochromocytomas in von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2 display distinct biochemical and clinical phenotypes. J Clin Endocrinol Metab 86:1999-2008
38. Ong KR, Woodward ER, Killick P, Lim C, Macdonald F, Maher ER (2007) Genotype-phenotype correlations in von Hippel-Lindau disease. Hum Mutat 28:143-149
39. Langrehr JM, Bahra M, Kristiansen G, Neumann HP, Neumann LM, Plockinger U, Lopez-Hanninen E (2007) Neuroendocrine tumor of the pancreas and bilateral adrenal pheochromocytomas. A rare manifestation of von Hippel-Lindau disease in childhood. J Pediatr Surg 42:1291-1294
40. Eisenhofer G, Keiser H, Friberg P, Mezey E, Huynh TT, Hiremagalur B, Ellingson T, Duddempudi S, Eijsbouts A, Lenders JW (1998) Plasma metanephrines are markers of pheochromocytoma produced by catechol-O-methyltransferase within tumors. J Clin Endocrinol Metab 83:2175-2185
41. Lenders JW, Pacak K, Walther MM, Linehan WM, Mannelli M, Friberg P, Keiser HR, Goldstein DS, Eisenhofer G (2002) Biochemical diagnosis of pheochromocytoma: Which test is best? JAMA 287:1427-1434
42. Sawka AM, Jaeschke R, Singh RJ, Young WF Jr (2003) A comparison of biochemical tests for pheochromocytoma: Measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endocrinol Metab 88:553-558
43. Eisenhofer G, Goldstein DS, Sullivan P, Csako G, Brouwers FM, Lai EW, Adams KT, Pacak K (2005) Biochemical and clinical manifestations of dopamine-producing paragangliomas: Utility of plasma methoxytyramine. J Clin Endocrinol Metab 90:2068-2075
44. Davidson DF (2005) Elevated urinary dopamine in adults and children. Ann Clin Biochem 42:200-207
45. Seefelder C, Sparks JW, Chirnomas D, Diller L, Shamberger RC (2005) Perioperative management of a child with severe hypertension from a catecholamine secreting neuroblastoma. Paediatr Anaesth 15:606-610
46. Lenders JW, Willemsen JJ, Eisenhofer G, Ross HA, Pacak K, Timmers HJ, Sweep CG (2007) Is supine rest necessary before blood sampling for plasma metanephrines? Clin Chem 53:352-354
47. Eisenhofer G, Goldstein DS, Walther MM, Friberg P, Lenders JW, Keiser HR, Pacak K (2003) Biochemical diagnosis of pheochromocytoma: How to distinguish true- from false-positive test results. J Clin Endocrinol Metab 88:2656-2666
48. Bravo EL, Tarazi RC, Fouad FM, Vidt DG, Gifford RW Jr (1981) Clonidine-suppression test: A useful aid in the diagnosis of pheochromocytoma. N Engl J Med 305:623-626
49. Pacak K, Linehan WM, Eisenhofer G, Walther MM, Goldstein DS (2001) Recent advances in genetics, diagnosis, localization, and treatment of pheochromocytoma. Ann Intern Med 134:315-329
50. Pacak K, Ilias I, Adams KT, Eisenhofer G (2005) Biochemical diagnosis, localization and management of pheochromocytoma: Focus on multiple endocrine neoplasia type 2 in relation to other hereditary syndromes and sporadic forms of the tumour. J Intern Med 257:60-68
51. Nielsen JT, Nielsen BV, Rehling M (1996) Location of adrenal medullary pheochromocytoma by I-123 metaiodobenzylguanidine SPECT. Clin Nucl Med 21:695-699
52. van der Harst E, de Herder WW, Bruining HA, Bonjer HJ, de Krijger RR, Lamberts SW, van de Meiracker AH, Boomsma F, Stijnen T, Krenning EP, Bosman FT, Kwekkeboom DJ (2001) [(123)I]metaiodobenzylguanidine and [(111)In]octreotide uptake in benign and malignant pheochromocytomas. J Clin Endocrinol Metab 86:685-693
53. Howman-Giles R, Shaw PJ, Uren RF, Chung DK (2007) Neuroblastoma and other neuroendocrine tumors. Semin Nucl Med 37:286-302
54. Solanki KK, Bomanji J, Moyes J, Mather SJ, Trainer PJ, Britton KE (1992) A pharmacological guide to medicines which interfere with the biodistribution of radiolabelled meta-iodobenzylguanidine (MIBG). Nucl Med Commun 13:513-521
55. Ilias I, Pacak K (2004) Current approaches and recommended algorithm for the diagnostic localization of pheochromocytoma. J Clin Endocrinol Metab 89:479-491
56. Timmers HJ, Kozupa A, Chen CC, Carrasquillo JA, Ling A, Eisenhofer G, Adams KT, Solis D, Lenders JW, Pacak K (2007) Superiority of fluorodeoxyglucose positron emission tomography to other functional imaging techniques in the evaluation of metastatic SDHB-associated pheochromocytoma and paraganglioma. J Clin Oncol 25:2262-2269
57. Goldstein RE, O'Neill JA Jr, Holcomb GW III, Morgan WM III, Neblett WW III, Oates JA, Brown N, Nadeau J, Smith B, Page DL, Abumrad NN, Scott HW Jr (1999) Clinical experience over 48 years with pheochromocytoma. Ann Surg 229:755-764
58. Pacak K (2007) Preoperative management of the pheochromocytoma patient. J Clin Endocrinol Metab 92:4069-4079
59. Ein SH, Pullerits J, Creighton R, Balfe JW (1997) Pediatric pheochromocytoma. A 36-year review. Pediatr Surg Int 12:595-598
60. Brunt LM, Lairmore TC, Doherty GM, Quasebarth MA, DeBenedetti M, Moley JF (2002) Adrenalectomy for familial pheochromocytoma in the laparoscopic era. Ann Surg 235:713-720
61. Diner EK, Franks ME, Behari A, Linehan WM, Walther MM (2005) Partial adrenalectomy: The National Cancer Institute experience. Urology 66:19-23
62. Reddy VS, O'Neill JA Jr, Holcomb GW III, Neblett WW III, Pietsch JB, Morgan WM III, Goldstein RE (2000) Twenty-five-year surgical experience with pheochromocytoma in children. Am Surg 66:1085-1091
63. Chrisoulidou A, Kaltsas G, Ilias I, Grossman AB (2007) The diagnosis and management of malignant phaeochromocytoma and paraganglioma. Endocr Relat Cancer 14:569-585
64. Scholz T, Eisenhofer G, Pacak K, Dralle H, Lehnert H (2007) Clinical review: Current treatment of malignant pheochromocytoma. J Clin Endocrinol Metab 92:1217-1225
65. van Essen M, Krenning EP, Kooij PP, Bakker WH, Feelders RA, de Herder WW, Wolbers JG, Kwekkeboom DJ (2006) Effects of therapy with [177Lu-DOTA0, Tyr3]octreotate in patients with paraganglioma, meningioma, small cell lung carcinoma, and melanoma. J Nucl Med 47:1599-1606
66. Zelinka T, Eisenhofer G. Pacak K (2007) Pheochromocytoma as a catecholamine producing tumor: Implications for clinical practice. Stress 10:195-203