Design and evaluation of a novel matrix type multiple units as biphasic gastroretentive drug delivery systems

AAPS PharmSciTech

Volumn 9, Issue 4, 2008, Pages 1253-1261

  Lingam, Meka ^a   Ashok, Thadisetty ^a   Venkateswarlu, Vobalaboina ^a   Madhusudan Rao, Yamsani ^a  

^a KAKATIYA UNIVERSITY   (India)

Author keywords

Biphasic release; Controlled release; Dissolution; Polymeric coating

Indexed keywords

BICARBONATE; CARBON DIOXIDE; CELLULOSE DERIVATIVE; CROSCARMELLOSE; EUDRAGIT; POLYMETHACRYLIC ACID; RANITIDINE; UNCLASSIFIED DRUG; DRUG;

ARTICLE; BIPHASIC GASTRORETENTIVE FLOATING DRUG DELIVERY SYSTEM; CONTROLLED DRUG RELEASE; DIRECT COMPRESSION; DISSOLUTION; DOSE CALCULATION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG RETENTION; DRUG STABILITY; EFFERVESCENT TABLET; FLOATING LOADING DOSE COMPONENT; FLOATING PROLONGED RELEASE COMPONENT; GAS; KINETICS; LOADING DRUG DOSE; MATRIX TABLET; QUALITY CONTROL; STOMACH; SUSTAINED RELEASE FORMULATION; TABLET COMPRESSION; TABLET FORMULATION; TABLET FRIABILITY; TIME; ADULT; BLOOD; HALF LIFE TIME; HUMAN; MALE; METABOLISM; SCANNING ELECTRON MICROSCOPY; SOLUBILITY;

ADULT; DRUG DELIVERY SYSTEMS; HALF-LIFE; HUMANS; MALE; MICROSCOPY, ELECTRON, SCANNING; PHARMACEUTICAL PREPARATIONS; SOLUBILITY; STOMACH;

EID: 63649160630     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-008-9173-2     Document Type: Article

References (22)

1. A. C. Shah. Design of oral sustained release drug delivery systems: In vitro/in vivo Considerations. In A. Yacobi, and E. Halperin-Walega (eds.), Oral Sustained Release Formulation Design and Evaluation, Pergamon, New York, 1988, pp. 35-56.
2. A. Rubinstein, V. H. K. Li, P. Gruber, and J. R. Robinson. Gastrointestinal-physiological variables affecting the performance of oral sustained release dosage forms. In A. Yacobi, and E. Halperin-Walega (eds.), Oral Sustained Release Formulation Design and Evaluation, Pergamon, New York, 1988, pp. 125-156.
3. M. Mayersohn. Principles of drug absorption. In G. C. Banker, and C. T. Rhodes (eds.), Modern Pharmaceutics, Marcel Dekker, New York, 1979, pp. 23-89.
4. P. K. Gupta, and J. R. Robinson. Oral controlled-release delivery. In A. Kydonieus (ed.), Treatise on Controlled Drug Delivery, Marcel Dekker, New York, 1992, pp. 255-313.
5. N. Rouge, E. T. Cole, E. Doelker, and P. Buri. Screening of potentially floating excipients for Minitablets. S.T.P. Pharm. Sci. 7:386-392 (1997).
6. L. Maggi, E. O. Machiste, M. L. Torre, and U. Conte. Formulation of biphasic release tablets containing slightly soluble drugs. Eur. J. Pharm. Biopharm. 48:37-42 (1999).
7. S. Somade, and K. Singh. Comparative evaluation of wet granulation and direct compression methods for preparation of controlled release ranitidine HCL tablets. Indian J. Pharm. Sci. 64:285 (2002).
8. K. Lauritsen. Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal diseases. Clin. Pharmacokinet. 1911-31:94-125 (1990).
9. S. Grant. Ranitidine: An updated review of its pharmacodynamics and pharmacokinetic properties and therapeutic use in peptic ulcer and other allied diseases. Drugs. 37:801-870 (1989).
10. A. Basit, and L. Lacey. Colonic metabolism of ranitidine: Implications for its delivery and absorption. Int. J. Pharm. 227:157-165 (2001).
11. M. Coffin, and A. Parr, inventors. Glaxo Inc. Ranitidine solid dosage form. US patent 5 407 687. April 18, 1995.
12. J. G. Wagner. Biopharmaceutics and pharmacokinetics. 1st ed. Org. Intelligence publications, 22, 1971, pp. 148-157.
13. A. M. Hamid, M. S. Harris, T. Jaweria, and I. Y. Rabia. Once-daily tablet formulation and in vitro release evaluation of cefpodoxime using hydroxypropyl methylcellulose: A technical note. AAPS PharmSciTech. 7: (3) Article 78 (2006).
14. P. Costa, and J. M. S. Lobo. Modeling and comparison dissolution profiles. Int. J. Pharm. 13:123-133 (2001).
15. J. W. Moore, and H. H. Flanner. Mathematical comparison of curves with an emphasis on in- vitro dissolution profiles. Pharm. Tech. 20:64-74 (1996).
16. P. Colombo, R. Bettini, P. Santi, and N. A. Peppas. Swellable matrices for controlled drug delivery: Gel-layer behaviour, mechanisms and optimal performance. PSTT. 3:198-204 (2000).
17. S. Kiil, and K. Dam-Johansen. Controlled drug delivery from swellable Hydroxyl propyl methylcellulose matrices: Model-based analysis of observed radial front movements. J. Contr. Release. 90:1-21 (2003).
18. I. Krögel, and R. Bodmeier. Floating or pulsatile drug delivery systems based on coated effervescent cores. Int. J. Pharm. 187:175-184 (1999).
19. V. Iannuccelli, G. Coppi, M. T. Bernabei, and R. Cameroni. Air compartment multipleunit system for prolonged gastric residence. Part I. Formulation study. Int. J. Pharm. 174:47-54 (1998).
20. I. Ghebre-Sellassie, R. U. Nesbitt, and J. Wang. Eudragit aqueous dispersions as pharmaceutical controlled release coatings. In J. W. McGinity (ed.), Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, 2nd ed., Marcel Dekker, New York, pp. 267-286.
21. K. H. Bauer, K. Lehmann, H. P. Osterwald, and G. Rothgang. Coated Pharmaceutical Dosage Forms, Medpharm Scientific, Stuttgart, 1998, pp. 63-119.
22. M. Ichigawa, S. Watanabe, and Y. Miyake. A new multiple-unit oral floating dosage system. I. Preparation and in vitro evaluation of floating and sustained release characteristics. J. Pharm. Sci. 80:1062-1066 (1991).