Impact of determination of hepatitis B virus subgenotype and pre-core/ core-promoter mutation for the prediction of acute exacerbation of asymptomatic carriers

Hepatology Research

Volumn 39, Issue 4, 2009, Pages 341-345

  Ikegami, Tadashi ^a   Matsuki, Yasuhiko ^a   Tanaka, Yasuhito ^b   Mizokami, Masashi ^b   Honda, Akira ^c   Hirayama, Takeshi ^a   Saito, Yoshifumi ^a   Matsuzaki, Yasushi ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b Tsukuba Gakuen Hospital   (Japan)

^c NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Chronic hepatitis; Fulminant hepatitis; Hepatits B virus (HBV); Pre core core promoter mutations; Subgenotype

Indexed keywords

ALANINE AMINOTRANSFERASE; BETA INTERFERON; HEPATITIS B ANTIGEN; HEPATITIS B(E) ANTIBODY; LAMIVUDINE; METHYLPREDNISOLONE; VIRUS DNA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; BIOARTIFICIAL LIVER; CASE REPORT; DISEASE EXACERBATION; FAMILIAL DISEASE; FATIGUE; GENE MUTATION; GENETIC ANALYSIS; GENOTYPE; HEMODIAFILTRATION; HEPATIC ENCEPHALOPATHY; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HYPERBILIRUBINEMIA; JAUNDICE; LIVER ATROPHY; LIVER DYSFUNCTION; MALE; NONHUMAN; PLASMAPHERESIS; PRIORITY JOURNAL; PROGNOSIS; PROTHROMBIN TIME;

EID: 63649151471     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2008.00460.x     Document Type: Article

References (12)

1. Ozasa A, Tanaka Y, Orito E et al. Influence of genotypes and precore mutations on fulminant or chronic outcome of acute hepatitis B virus infection. Hepatology 2006; 44: 326-34.
2. Yoshiba M, Inoue K, Sekiyama K, Koh I. Favorable effect of new artificial liver support on survival of patients with fulminant hepatic failure. Artif Organs 1996; 20: 1169-72.
3. Masuhara M, Yagawa T, Aoyagi M et al. HBV-related fulminant hepatic failure: Successful intensive medical therapy in a candidate for liver transplantation. J Gastroenterol 2001; 36: 350-3.
4. Abe A, Inoue K, Tanaka T et al. Quantitation of hepatitis B virus genomic DNA by real-time detection PCR. J Clin Microbiol 1999; 37: 2899-903.
5. Saitou N, Nei M. The neighbor-joining method: A new method for reconstructing phylogenetic trees. Mol Biol Evol 1987; 4: 406-25.
6. Sugauchi F, Orito E, Ichida T et al. Epidemiologic and virologic characteristics of hepatitis B virus genotype B having the recombination with genotype C. Gastroenterology 2003; 124: 925-32.
7. Tanaka Y, Orito E, Yuen MF et al. Two subtypes (subgenotypes) of hepatitis B virus genotype C: A novel subtyping assay based on restriction fragment length polymorphism. Hepatol Res 2005; 33: 216-24.
8. Takeda Y, Katano Y, Hayashi K et al. Difference of HBV genotype distribution between acute hepatitis and chronic hepatitis in Japan. Infection 2006; 34: 201-7.
9. Hayashi K, Katano Y, Takeda Y et al. Comparison of hepatitis B virus subgenotypes in patients with acute and chronic hepatitis B and absence of lamivudine-resistant strains in acute hepatitis B in Japan. J Med Virol 2007; 79: 366-73.
10. Hagiwara S, Kudo M, Minami Y et al. Clinical significance of the genotype and core promoter/pre-core mutations in hepatitis B virus carriers. Intervirology 2006; 49: 200-6.
11. Sugiyama M, Tanaka Y, Kato T et al. Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens. Hepatology 2006; 44: 915-24.
12. Imamura T, Yokosuka O, Kurihara T et al. Distribution of hepatitis B viral genotypes and mutations in the core promoter and precore regions in acute forms of liver disease in patients from Chiba, Japan. Gut 2003; 52: 1630-7.