Time-course changes in neural cell apoptosis in the rat fetal brain from dams treated with 6-mercaptopurine (6-MP)

Histology and Histopathology

Volumn 24, Issue 3, 2009, Pages 317-324

  Kanemitsu, Hiroyuki ^a   Yamauchi, H ^a   Komatsu, M ^b   Yamamoto, S ^b   Okazaki, S ^b   Nakayama, H ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Research Center Inc   (Japan)

Author keywords

6 mercaptopurine; Apoptosis; Fetal brain; Fetotoxicity; Neural cell

Indexed keywords

BROXURIDINE; CASPASE 3; DNA; MERCAPTOPURINE; TERATOGENIC AGENT;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN DEVELOPMENT; BRAIN WEIGHT; CELL COUNT; CELL NUCLEUS; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; ELECTRON MICROSCOPY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME DEGRADATION; FETUS; IMMUNOHISTOCHEMISTRY; MITOSIS; NERVE CELL; NICK END LABELING; NONHUMAN; PERINATAL DRUG EXPOSURE; PREGNANCY; RAT; TELENCEPHALON; THICKNESS; TIME; WESTERN BLOTTING; ANIMAL; ANIMAL EMBRYO; BRAIN; CELL DEATH; DRUG EFFECT; FEMALE; METABOLISM; ORGAN SIZE; PATHOLOGY; PRENATAL DEVELOPMENT; PRENATAL EXPOSURE; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

RATTUS;

6-MERCAPTOPURINE; ANIMALS; APOPTOSIS; BRAIN; CASPASE 3; CELL DEATH; DNA FRAGMENTATION; EMBRYO, MAMMALIAN; FEMALE; FETUS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; NEURONS; ORGAN SIZE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; TERATOGENS; TIME FACTORS;

EID: 63649145407     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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