In-channel focusing of flowing microparticles utilizing hydrodynamic filtration

Microfluidics and Nanofluidics

Volumn 6, Issue 4, 2009, Pages 571-576

  Aoki, Ryota ^a   Yamada, Masumi ^b   Yasuda, Masahiro ^a   Seki, Minoru ^a,c  

^a Osaka Prefecture University   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

Continuous operation; Flow cytometry; Hydrodynamic filtration; Microfluidics; Particle focusing

Indexed keywords

BIOASSAY; FLOW CYTOMETRY; FOCUSING; HYDRODYNAMICS; MICROCHANNELS; MICROFLUIDICS; POROUS MATERIALS;

CONTINUOUS OPERATION; FLOW SPEED; FLUID FLOWS; IN CHANNELS; MICRO FLUIDIC SYSTEMS; MICROPARTICLES; PARTICLE FOCUSING; PHYSICAL FORCES; SHEATH FLOWS;

FLUID DYNAMICS;

EID: 63649141285     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-008-0334-0     Document Type: Article

References (19)

1. Bird RB, Stewart WE, Lightfoot EN (2002) Transport phenomena, 2nd edn. Wiley, New York, p 51
2. Constantinescu VN (1995) Laminar viscous flow. Springer, New York, pp 109-137
3. Di Carlo D, Irimia D, Tompkins RG, Toner M (2007) Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc Natl Acad Sci USA 104:18892-18897
4. Duffy DC, McDonald JC, Schueller OJA, Whitesides GM (1998) Rapid prototyping of microfluidic systems in poly(dimethylsiloxane). Anal Chem 70:4974-4984
5. Knight JB, Vishwanath A, Brody JP, Austin RH (1998) Hydrodynamic focusing on a silicon chip: Mixing nanoliters in microseconds. Phys Rev Lett 80:3863-3866
6. McClain MA, Culbertson CT, Jacobson SC, Ramsey JM (2001) Flow cytometry of Escherichia coli on microfluidic devices. Anal Chem 73:5334-5338
7. Rodriguez-Trujillo R, Mills CA, Samitier J, Gomila G (2007) Low cost micro-Coulter counter with hydrodynamic focusing. Microfluid Nanofluid 3:171-176
8. Schrum DP, Culbertson CT, Jacobson SC, Ramsey JM (1999) Microchip flow cytometry using electrokinetic focusing. Anal Chem 71:4173-4177
9. Shi JJ, Mao XL, Ahmed D, Colletti A, Huang TJ (2008) Focusing microparticles in a microfluidic channel with standing surface acoustic waves (SSAW). Lab Chip 8:221-223
10. Stiles T, Fallon R, Vestad T, Oakey J, Marr DWM, Squier J, Jimenez R (2005) Hydrodynamic focusing for vacuum-pumped microfluidics. Microfluid Nanofluid 1:280-283
11. Wang Z, El-Ali J, Engelund M, Gotsaed T, Perch-Nielsen IR, Mogensen KB, Snakenborg D, Kutter JP, Wolff A (2004) Measurements of scattered light on a microchip flow cytometer with integrated polymer based optical elements. Lab Chip 4:372-377
12. Wang TH, Peng YH, Zhang CY, Wong PK, Ho CM (2005) Single-molecule tracing on a fluidic microchip for quantitative detection of low-abundance nucleic acids. J Am Chem Soc 127:5354-5359
13. Wang L, Flanagan LA, Jeon NL, Monuki E, Lee AP (2007) Dielectrophoresis switching with vertical sidewall electrodes for microfluidic flow cytometry. Lab Chip 7:1114-1120
14. Wolff A, Perch-Nielsen IR, Larsen UD, Friis P, Goranovic G, Poulsen CR, Kutter JP, Telleman P (2003) Integrating advanced functionality in a microfabricated high-throughput fluorescent-activated cell sorter. Lab Chip 3:22-27
15. Xuan XC, Li DQ (2005) Focused electrophoretic motion and selected electrokinetic dispensing of particles and cells in cross-microchannels. Electrophoresis 26:3552-3560
16. Yamada M, Seki M (2005) Hydrodynamic filtration for on-chip particle concentration and classification utilizing microfluidics. Lab Chip 5:1233-1239
17. Yamada M, Seki M (2006) Microfluidic particle sorter employing flow splitting and recombining. Anal Chem 78:1357-1362
18. Yamada M, Kano K, Tsuda Y, Kobayashi J, Yamato M, Seki M, Okano T (2007) Microfluidic devices for size-dependent separation of liver cells. Biomed Microdevices 9:637-645
19. Yamada M, Kobayashi J, Yamato M, Seki M, Okano T (2008) Millisecond treatment of cells using microfluidic devices via two-step carrier-medium exchange. Lab Chip 8:772-778