Parainfluenza virus type 3 pneumonia in bone marrow transplant recipients: Multiple small nodules in high-resolution lung computed tomography scans provide a radiological clue to diagnosis

Clinical Infectious Diseases

Volumn 48, Issue 7, 2009, Pages 905-909

  Ferguson, Patricia E ^a,c   Sorrell, Tania C ^a   Bradstock, Kenneth F ^b   Carr, Peter ^c   Gilroy, Nicole M ^a  

^a Centre for Infectious Diseases and Microbiology   (Australia)

^b Bone Marrow Transplant Service   (Australia)

^c WESTMEAD HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

VORICONAZOLE;

ADOLESCENT; ADULT; ANIMAL CELL; ARTICLE; BONE MARROW TRANSPLANTATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; HUMAN CELL; LUNG ASPERGILLOSIS; LUNG CAVITATION; MALE; NONHUMAN; PARAINFLUENZA VIRUS 3; PRIORITY JOURNAL; PROPHYLAXIS; VIRUS PNEUMONIA; COMPUTER ASSISTED TOMOGRAPHY; HUMAN PARAINFLUENZA VIRUS 3; LUNG; MIDDLE AGED; MULTIPLE PULMONARY NODULES; PNEUMONIA, VIRAL; RADIOGRAPHY; RESPIROVIRUS INFECTIONS;

ADOLESCENT; ADULT; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LUNG; MALE; MIDDLE AGED; MULTIPLE PULMONARY NODULES; PARAINFLUENZA VIRUS 3, HUMAN; PNEUMONIA, VIRAL; RESPIROVIRUS INFECTIONS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 63649110434     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/597297     Document Type: Article

References (19)

1. Roghmann M, Ball K, Erdman D, Lovchik J, Anderson LJ, Edelman R. Active surveillance for respiratory virus infections in adults who have undergone bone marrow and peripheral blood stem cell transplantation. Bone Marrow Transplantation 2003;32:1085-8.
2. Nichols WG, Corey L, Gooley T, Davis C, Boeckh M. Parainfluenza virus infections after hematopoietic stem cell transplantation: risk factors, response to antiviral therapy, and effect on transplant outcome. Blood 2001;98:573-8.
3. Lewis VA, Champlin R, Englund J, et al. Respiratory disease due to parainfluenza virus in adult bone marrow transplant recipients. Clin Infect Dis 1996;23:1033-7.
4. Marx A, Gary HE Jr, Marston BJ, et al. Parainfluenza virus infection among adults hospitalized for lower respiratory tract infection. Clin Infect Dis 1999;29:134-40.
5. Zambon M, Bull T, Sadler CJ, Goldman JM, Ward KN. Molecular epidemiology of two consecutive outbreaks of parainfluenza 3 in a bone marrow transplant unit. J Clin Microbiol 1998;36:2289-93.
6. Ferguson P, Gilroy N, Dwyer D, Bradstock K. High mortality outbreak from parainfluenza virus type 3 on a haematopoietic stem cell transplant unit. Intern Med J 2005;35:A86.
7. Rubin RH, Greene R. Clinical approach to the compromised host with fever and pulmonary infiltrates. In: Rubin RH, Lowell S, eds. Clinical approach to infection in the immunocompromised host. 4th ed. New York: Young Kluwer Academic/Plenum, 2002:116.
8. Franquet T, Müller NL, Giménez A, Martínez S, Madrid M, Domingo P. Infectious pulmonary nodules in immunocompromised patients: usefulness of computed tomography in predicting their etiology. J Comput Assist Tomogr 2003;27:461-8.
9. Lambert SB, Whiley DM, O'Neill NT, et al. Comparing nose-throat swabs and nasopharyngeal aspirates collected from children with symptoms for respiratory virus identification using real-time polymerase chain reaction. Pediatrics 2008;122:e615-20.
10. Maertzdorf J, Wang CK, Brown IB, et al. Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages. J Clin Microbiol 2004;42:981-6.
11. Arden KE, McErlean P, Nissen MD, Sloots TP, Mackay IM. Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections. J Med Virol 2006;78:1232-40.
12. Sloots TP, McErlean P, Speicher DJ, Arden KE, Nissen MD, Mackay IM. Evidence of human coronavirus HKU1 and human bocavirus in Australian children. J Clin Virol 2006;35:99-102.
13. Gaynor AM, Nissen MD, Whiley DM, et al. Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathog 2007;3:e64.
14. Bialasiewicz S, Whiley DM, Lambert SB, Gould A, Nissen MD, Sloots TP. Development and evaluation of real-time PCR assays for the detection of the newly identified KI and WU polyomaviruses. J Clin Virol 2007;40:9-14.
15. Bialasiewicz S, Whiley DM, Lambert SB, et al. Presence of the newly discovered human polyomaviruses KI and WU in Australian patients with acute respiratory tract infection. J Clin Virol 2008;41:63-8.
16. Oh YW, Effmann EL, Godwin JD. Pulmonary infections in immunocompromised hosts: the importance of correlating the conventional radiologic appearance with the clinical setting. Radiology 2000;217:647-56.
17. Templeton KE, Scheltinga SA, Beersma MF, Kroes AC, Claas EC. Rapid and sensitive method using multiplex real-time PCR for diagnosis of infections by influenza A and influenza B viruses, respiratory syncytial virus, and parainfluenza viruses 1, 2, 3, and 4. J Clin Microbiol 2004;42:1564-9.
18. Oosterheert JJ, van Loon AM, Schuurman R, et al. Impact of rapid detection of viral and atypical bacterial pathogens by real-time polymerase chain reaction for patients with lower respiratory tract infection. Clin Infect Dis 2005;41:1438-44.
19. Maertens J, Theunissen K, Verhoef G, et al. Galactomannan and computed tomography-based preemptive antifungal therapy in neutropenic patients at high risk for invasive fungal infection: a prospective feasibility study. Clin Infect Dis 2005;41:1242-50.