Increased chymase-positive mast cells in children with crescentic glomerulonephritis

Pediatric Nephrology

Volumn 24, Issue 5, 2009, Pages 1071-1075

  Togawa, Hiroko ^a   Nakanishi, Koichi ^a   Shima, Yuko ^a   Obana, Mina ^a   Sako, Mayumi ^a   Nozu, Kandai ^b   Tanaka, Ryojiro ^c   Iijima, Kazumoto ^b   Yoshikawa, Norishige ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KOBE CHILDREN S HOSPITAL   (Japan)

Author keywords

Allografted kidney; Angiotensin II; Diabetic nephropathy; Immunoglobulin A nephropathy; Immunohistochemistry; Interstitial fibrosis; Rapidly progressive glomerulonephritis

Indexed keywords

CHYMASE;

ANAPHYLACTOID PURPURA; ARTICLE; CHILD; CRESCENTIC GLOMERULONEPHRITIS; DIABETIC NEPHROPATHY; FEMALE; FIBROSING ALVEOLITIS; GLOMERULONEPHRITIS; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOHISTOCHEMISTRY; KIDNEY ALLOGRAFT; KIDNEY BIOPSY; KIDNEY CORTEX; MAJOR CLINICAL STUDY; MALE; MAST CELL; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD; TISSUE LEVEL;

BIOPSY; CHILD; CHYMASES; DIABETIC NEPHROPATHIES; FEMALE; FIBROSIS; GLOMERULAR FILTRATION RATE; GLOMERULONEPHRITIS, IGA; GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MAST CELLS; NEPHRITIS; PURPURA, SCHOENLEIN-HENOCH;

EID: 63649107745     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-008-1044-2     Document Type: Article

References (13)

1. Yamada M, Ueda M, Naruko T, Tanabe S, Han YS, Ikura Y, Ogami M, Takai S, Miyazaki M (2001) Mast cell chymase expression and mast cell phenotypes in human rejected kidneys. Kidney Int 59:1374-1381
2. Ritz E (2003) Chymase: A potential culprit in diabetic nephropathy? J Am Soc Nephrol 14:1738-1747
3. Huang XR, Chen WY, Truong LD, Lan HY (2003) Chymase is upregulated in diabetic nephropathy: Implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease. J Am Soc Nephrol 14:1738-1747
4. Miyake-Ogawa C, Miyazaki M, Abe K, Harada T, Ozono Y, Sakai H, Koji T, Kohno S (2005) Tissue-specific expression of renin-angiotensin system components in IgA nephropathy. Am J Nephrol 25:1-12
5. Racusen LC, Solez K, Colvin RB, Bonsib SM, Castro MC, Cavallo T, Croker BP, Demetris AJ, Drachenberg CB, Fogo AB, Furness P, Gaber LW, Gibson IW, Glotz D, Goldberg JC, Grande J, Halloran PF, Hansen HE, Hartley B, Hayry PJ, Hill CM, Hoffman EO, Hunsicker LG, Lindblad AS, Marcussen N, Mihatsch MJ, Nadasdy T, Nickerson P, Olsen ST, Papadimitriou JC, Randhawa PS, Rayner DC, Roberts I, Rose S, Rush D, Salinas-Madrigal L, Salomon DR, Sund S, Taskinen E, Trpkiv K, Yamaguchi Y (1999) The Banff 97 working classification of renal allograft pathology. Kidney Int 55:713-723
6. Churg J, Bernstein J, Glassock RJ (1995) Renal disease: Classification and atlas of glomerular diseases, 2nd edn. Igaku-shoin Medical Publishers Tokyo
7. Yoshikawa N, Nakanishi K, Iijima K (2001) Henoch-Schönlein purpura. In: Neilson EG, Couser WG (eds) Immunologic renal diseases, 2nd edn. Lippincott Williams & Wilkins, Philadelphia, pp 1127-1140
8. Tóth T, Tóth-Jakatics R, Jimi S, Ihara M, Urata H, Takebayashi S (1999) Mast cells in rapidly progressive glomerulonephritis. J Am Soc Nephrol 10:1498-1505
9. Ehara T, Shigematsu H (1998) Contribution of mast cells to the tubulointerstitial lesions in IgA nephritis. Kidney Int 54:1675-1683
10. Ikezumi Y, Suzuki T, Imai N, Ueno M, Narita I, Kawachi H, Shimizu F, Nikolic-Paterson DJ, Uchiyama M (2006) Histological differences in new-onset IgA nephropathy between children and adults. Nephrol Dial Transplant 21:3466-3474
11. Blank U, Essig M, Scandiuzzi L, Benhamou M, Kanamaru Y (2007) Mast cells and inflammatory kidney disease. Immunol Rev 217:79-95
12. Tchougounova E, Lundequist A, Fajardo I, Winberg JO, Abrink M, Pejler G (2005) A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2. J Biol Chem 280:9291-9296
13. Hollenberg NK, Fisher ND, Price DA (1998) Pathways for angiotensin II generation in intact human tissue: Evidence from comparative pharmacological interruption of the renin system. Hypertension 32:387-392