Development of a Stable Closed Femoral Fracture Model in Mice

Journal of Surgical Research

Volumn 153, Issue 1, 2009, Pages 71-75

  Holstein, Joerg H ^a   Matthys, Romano ^b   Histing, Tina ^a   Becker, Steven C ^a   Fiedler, Martin ^a   Garcia, Patric ^a   Meier, Christoph ^a   Pohlemann, Tim ^a   Menger, Michael D ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b AO Development Institute   (Switzerland)

Author keywords

biomechanical testing; closed murine fracture model; fracture healing; histomorphometric analysis; intramedullary screw

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE SCREW; FEMUR FRACTURE; FRACTURE HEALING; INTRAMEDULLARY NAILING; MOUSE; NONHUMAN; OSTEOSYNTHESIS; PRIORITY JOURNAL; TREATMENT OUTCOME;

ANIMALS; BIOMECHANICS; BONE SCREWS; CADAVER; DISEASE MODELS, ANIMAL; FEMORAL FRACTURES; FRACTURE FIXATION, INTRAMEDULLARY; FRACTURE HEALING; MICE;

EID: 63649089815     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.02.042     Document Type: Article

References (9)

1. Jacenko O., and Olsen B.R. Transgenic mouse models in studies of skeletal disorders. J Rheumatol 43S (1995) 39
2. Bonnarens F., and Einhorn T.A. Production of a standard closed fracture in laboratory animal bone. J Orthop Res 2 (1984) 97
3. Cheung K., Kalurachi K., Andrew G., et al. An external fixed femoral fracture model for mice. J Orthop Res 21 (2003) 685
4. Holstein J.H., Menger M.D., Culemann U., et al. Development of a locking femur nail for mice. J Biomech 40 (2007) 215
5. Augat P., Margevicius K., Simon J., et al. Local tissue properties in bone healing: Influence of size and stability of the osteotomy gap. J Orthop Res 16 (1998) 475
6. Manigrasso M.B., and O'Connor P.J. Characterization of a closed femur fracture model in mice. J Orthop Trauma 18 (2004) 687
7. Carter D.R., Beaupre G.S., Giori N.J., et al. Mechanobiology of skeletal regeneration. Clin Orthop Relat Res 355S (1998) 41
8. Parfitt A.M., Drezner M.K., Glorieux F.H., et al. Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2 (1987) 595
9. Goodship A.E., and Kenwright J. The influence of induced micromovement upon the healing of experimental tibial fractures. J Bone Joint Surg 67B (1985) 650