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Volumn 15, Issue 6, 2009, Pages 1848-1852

HER-2as a target for breast cancer therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIRUBICIN; FLUOROURACIL; LAPATINIB; NAVELBINE; PACLITAXEL; PERTUZUMAB; TANESPIMYCIN; TAXANE DERIVATIVE; TRASTUZUMAB; ERBB2 PROTEIN, HUMAN; MONOCLONAL ANTIBODY;

EID: 63549143099     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-08-1844     Document Type: Article
Times cited : (37)

References (38)
  • 1
    • 0022399581 scopus 로고    scopus 로고
    • Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
    • Coussens L, Yang-Feng TL, LiaoYC, et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science1985;230:1132-9.
    • Science1985;230 , pp. 1132-1139
    • Coussens, L.1    Yang-Feng, T.L.2    LiaoYC3
  • 2
    • 0022406444 scopus 로고
    • Amplification of a novel v-erb B-related gene in a human mammary carcinoma
    • King CR, Kraus MH, Aaronson SA. Amplification of a novel v-erb B-related gene in a human mammary carcinoma. Science 1985;229:974-6.
    • (1985) Science , vol.229 , pp. 974-976
    • King, C.R.1    Kraus, M.H.2    Aaronson, S.A.3
  • 4
    • 33847147313 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • Wolff AC, Hammond ME, Schwartz JN, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.J Clin Oncol 2007; 25: 118-45.
    • (2007) J Clin Oncol , vol.25 , pp. 118-145
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3
  • 5
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005;5:341 -54.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 6
    • 0028884413 scopus 로고
    • Requirement for neuregulin receptor erbB2 in neural and cardiac development
    • Lee KF, Simon H, Chen H, Bates B, Hung MC, Hauser C. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 1995;378: 394-8.
    • (1995) Nature , vol.378 , pp. 394-398
    • Lee, K.F.1    Simon, H.2    Chen, H.3    Bates, B.4    Hung, M.C.5    Hauser, C.6
  • 7
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • Baselga J, Norton L,Albanell J, Kim YM, Mendelsohn J. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res 1998; 58:2825-31.
    • (1998) Cancer Res , vol.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3    Kim, Y.M.4    Mendelsohn, J.5
  • 8
    • 63549138147 scopus 로고    scopus 로고
    • Slamon DJ, Leyland-Jones B, Shak S, et al. Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2 + /MBC) markedly increases anticancer activity: a randomised, multinational controlled phase III trial. J Clin Oncol Suppl 1998;16:abstract 377.
    • Slamon DJ, Leyland-Jones B, Shak S, et al. Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2 + /MBC) markedly increases anticancer activity: a randomised, multinational controlled phase III trial. J Clin Oncol Suppl 1998;16:abstract 377.
  • 9
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-92.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 10
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005; 353:1659-72.
    • (2005) N Engl J Med , vol.353 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 11
    • 26844536978 scopus 로고    scopus 로고
    • Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    • Romond EH, Perez EA, BryantJ, et al.Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 2005;353: 1673-84.
    • (2005) N Engl J Med , vol.353 , pp. 1673-1684
    • Romond, E.H.1    Perez, E.A.2    BryantJ3
  • 12
    • 63549146090 scopus 로고    scopus 로고
    • Perez EA, Romond EH, Suman VJ, et al. Updated results of the combined analysis of NCCTG N9831 and NSABP B-31 adjuvant chemotherapy with/without trastuzumab in patients with HER2-positive breast cancer. J Clin Oncol Suppl 2007;25: abstract 512.
    • Perez EA, Romond EH, Suman VJ, et al. Updated results of the combined analysis of NCCTG N9831 and NSABP B-31 adjuvant chemotherapy with/without trastuzumab in patients with HER2-positive breast cancer. J Clin Oncol Suppl 2007;25: abstract 512.
  • 13
    • 33845914783 scopus 로고    scopus 로고
    • 2-Year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positivebreastcancer: A randomised controlled trial
    • Smith I, Procter M, Gelber RD, et al. 2-Year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positivebreastcancer: a randomised controlled trial. Lancet2007;369:29-36.
    • Lancet2007;369 , pp. 29-36
    • Smith, I.1    Procter, M.2    Gelber, R.D.3
  • 14
    • 63549150974 scopus 로고    scopus 로고
    • Slamon D, EiermannW, Robert N, etal. BCIRG 006: 2nd interim analysis phase III randomized trial com-
    • Slamon D, EiermannW, Robert N, etal. BCIRG 006: 2nd interim analysis phase III randomized trial com-
  • 15
    • 63549130473 scopus 로고    scopus 로고
    • 2/neu positive early breast cancer patients. Breast Cancer ResTreat Suppl 2006;100: abstract 52.
    • 2/neu positive early breast cancer patients. Breast Cancer ResTreat Suppl 2006;100: abstract 52.
  • 16
    • 33344478381 scopus 로고    scopus 로고
    • Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
    • Joensuu H, Kellokumpu-Lehtinen PL, Bono P, et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N Engl J Med 2006; 354:809-20.
    • (2006) N Engl J Med , vol.354 , pp. 809-820
    • Joensuu, H.1    Kellokumpu-Lehtinen, P.L.2    Bono, P.3
  • 17
    • 63549099871 scopus 로고    scopus 로고
    • Spielmann M,RocheH, HumbletY, etal. 3-Year follow-up of trastuzumab following adjuvant chemotherapy in node positive HER2-positive breast cancer patients: results of the PACS-04 trial. Breast Cancer Res Treat Suppl 2007;106:abstract 72.
    • Spielmann M,RocheH, HumbletY, etal. 3-Year follow-up of trastuzumab following adjuvant chemotherapy in node positive HER2-positive breast cancer patients: results of the PACS-04 trial. Breast Cancer Res Treat Suppl 2007;106:abstract 72.
  • 18
    • 42449102271 scopus 로고    scopus 로고
    • Circumventing de novo and acquired resistance to trastuzumab: New hope for the care of ErbB2-positive breast cancer.Clin Breast
    • Piccart M. Circumventing de novo and acquired resistance to trastuzumab: new hope for the care of ErbB2-positive breast cancer.Clin Breast Cancer 2008;8:S100-113.
    • (2008) Cancer , vol.8
    • Piccart, M.1
  • 20
    • 34548531901 scopus 로고    scopus 로고
    • Trastuzumab-associated cardiac adverse effects in the herceptin adjuvant trial
    • Suter TM, Procter M, van Veldhuisen DJ, et al. Trastuzumab-associated cardiac adverse effects in the herceptin adjuvant trial. J Clin Oncol 2007;25: 3859-65.
    • (2007) J Clin Oncol , vol.25 , pp. 3859-3865
    • Suter, T.M.1    Procter, M.2    van Veldhuisen, D.J.3
  • 21
    • 63549090030 scopus 로고    scopus 로고
    • Rastogi P,Jeong J,Geyer CE, et al. Five year update of cardiac dysfunction on NSABP B-31, a randomized trial of sequential doxorubicin/ cyclophosphamide (AC)→paclitaxel (T) vs. AC→T with trastuzumab(H). J Clin Oncol Suppl 2007; 25: abstract LBA513.
    • Rastogi P,Jeong J,Geyer CE, et al. Five year update of cardiac dysfunction on NSABP B-31, a randomized trial of sequential doxorubicin/ cyclophosphamide (AC)→paclitaxel (T) vs. AC→T with trastuzumab(H). J Clin Oncol Suppl 2007; 25: abstract LBA513.
  • 22
    • 41649083764 scopus 로고    scopus 로고
    • Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central CancerTreatment Group N9831 adjuvant breast cancer trial
    • Perez EA, Suman VJ, Davidson NE, et al. Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central CancerTreatment Group N9831 adjuvant breast cancer trial. J Clin Oncol 2008;26: 1231-8.
    • (2008) J Clin Oncol , vol.26 , pp. 1231-1238
    • Perez, E.A.1    Suman, V.J.2    Davidson, N.E.3
  • 23
    • 41449105551 scopus 로고    scopus 로고
    • HER2 status and benefit from adjuvant trastuzumab in breast cancer
    • Paik S, Kim C, Wolmark N. HER2 status and benefit from adjuvant trastuzumab in breast cancer. N Engl J Med 2008; 358: 1409-11.
    • (2008) N Engl J Med , vol.358 , pp. 1409-1411
    • Paik, S.1    Kim, C.2    Wolmark, N.3
  • 24
    • 54449091620 scopus 로고    scopus 로고
    • Polysomy 17 in breast cancer: Clinicopathologic significance and impact on HER-2 testing
    • Vanden BI, Van Loo P, Drijkoningen M, et al. Polysomy 17 in breast cancer: clinicopathologic significance and impact on HER-2 testing. J Clin Oncol 2008;26:4869 -74.
    • (2008) J Clin Oncol , vol.26 , pp. 4869-4874
    • Vanden, B.I.1    Van Loo, P.2    Drijkoningen, M.3
  • 25
    • 54049096261 scopus 로고    scopus 로고
    • HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
    • Korkaya H, Paulson A, Iovino F,Wicha MS. HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 2008; 27: 6120-30.
    • (2008) Oncogene , vol.27 , pp. 6120-6130
    • Korkaya, H.1    Paulson, A.2    Iovino, F.3    Wicha, M.S.4
  • 26
    • 44049100934 scopus 로고    scopus 로고
    • Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
    • Li X, Lewis MT, Huang J, et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 2008;100:672 -9.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 672-679
    • Li, X.1    Lewis, M.T.2    Huang, J.3
  • 27
    • 42949157368 scopus 로고    scopus 로고
    • Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
    • Musolino A, Naldi N, BortesiB,etal. Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol 2008;26:1789 -96.
    • (2008) J Clin Oncol , vol.26 , pp. 1789-1796
    • Musolino, A.1    Naldi, N.2    BortesiB3
  • 28
    • 36849047716 scopus 로고    scopus 로고
    • Different prognostic value of cytokeratin-19 mRNA-positivecirculating tumor cells according to estrogen receptor and HER2 status in early breast cancer
    • Ignatiadis M, Xenidis N, Perraki M, et al. Different prognostic value of cytokeratin-19 mRNA-positivecirculating tumor cells according to estrogen receptor and HER2 status in early breast cancer. J Clin Oncol 2007;25:5194-202.
    • (2007) J Clin Oncol , vol.25 , pp. 5194-5202
    • Ignatiadis, M.1    Xenidis, N.2    Perraki, M.3
  • 29
    • 11144248359 scopus 로고    scopus 로고
    • Trastuzumab administration can effectively target chemotherapy-resistant cytokeratin-19 messenger RNA-positive tumor cells in the peripheral blood and bone marrow of patients with breast cancer
    • Bozionellou V, Mavroudis D, Perraki M, et al. Trastuzumab administration can effectively target chemotherapy-resistant cytokeratin-19 messenger RNA-positive tumor cells in the peripheral blood and bone marrow of patients with breast cancer. Clin Cancer Res 2004;10:8185 -94.
    • (2004) Clin Cancer Res , vol.10 , pp. 8185-8194
    • Bozionellou, V.1    Mavroudis, D.2    Perraki, M.3
  • 30
    • 63549136803 scopus 로고    scopus 로고
    • Baselga J, Cameron D, Miles D, et al. Objective response rate in a phase II multicenter trial of pertuzumab (P), a HER2 dimerization inhibiting monoclonal antibody, in combination with trastuzumab (T) in patients (pts) with HER2-positive metastatic breast cancer (MBC) which has progressed during treatment with T. J Clin Oncol Suppl 2008;25:abstract 1004.
    • Baselga J, Cameron D, Miles D, et al. Objective response rate in a phase II multicenter trial of pertuzumab (P), a HER2 dimerization inhibiting monoclonal antibody, in combination with trastuzumab (T) in patients (pts) with HER2-positive metastatic breast cancer (MBC) which has progressed during treatment with T. J Clin Oncol Suppl 2008;25:abstract 1004.
  • 31
    • 33845886440 scopus 로고    scopus 로고
    • Lapatinib plus capecitabine for HER2-positive advanced breast cancer
    • Geyer CE, Forster J, Lindquist D, et al. Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med 2006;355:2733 -43.
    • (2006) N Engl J Med , vol.355 , pp. 2733-2743
    • Geyer, C.E.1    Forster, J.2    Lindquist, D.3
  • 32
    • 35148885729 scopus 로고    scopus 로고
    • A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
    • Berns K, Horlings HM, Hennessy BT, et al. A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer. Cancer Cell 2007;12: 395-402.
    • (2007) Cancer Cell , vol.12 , pp. 395-402
    • Berns, K.1    Horlings, H.M.2    Hennessy, B.T.3
  • 33
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • Nagata Y, Lan KH, Zhou X, et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004;6:117 -27.
    • (2004) Cancer Cell , vol.6 , pp. 117-127
    • Nagata, Y.1    Lan, K.H.2    Zhou, X.3
  • 35
    • 5044221199 scopus 로고    scopus 로고
    • The efficacy of Herceptin therapies is influenced by the expression of other erb β receptors,their ligands and the activation of downstream signalling proteins
    • Smith BL, Chin D, Maltzman W, Crosby K, Hortobagyi GN, Bacus SS. The efficacy of Herceptin therapies is influenced by the expression of other erb β receptors,their ligands and the activation of downstream signalling proteins. Br J Cancer 2004; 91: 1190-4.
    • (2004) Br J Cancer , vol.91 , pp. 1190-1194
    • Smith, B.L.1    Chin, D.2    Maltzman, W.3    Crosby, K.4    Hortobagyi, G.N.5    Bacus, S.S.6
  • 36
    • 63549116574 scopus 로고    scopus 로고
    • Pegram M, Chan D, Dichmann RA, et al. Phase II combined biological therapy targeting the HER2 proto-oncogene and the vascular endothelial growth factor using trastuzumab (T) and bevacizumab (B) as first line treatment of HER2-amplified breast cancer. Breast Cancer Res Treat Suppl 2006;100: abstract 301.
    • Pegram M, Chan D, Dichmann RA, et al. Phase II combined biological therapy targeting the HER2 proto-oncogene and the vascular endothelial growth factor using trastuzumab (T) and bevacizumab (B) as first line treatment of HER2-amplified breast cancer. Breast Cancer Res Treat Suppl 2006;100: abstract 301.
  • 37
    • 63549116928 scopus 로고    scopus 로고
    • Mackey J, Kaufman B, Clemens M, et al. Trastuzumab prolongs progression-free survival in hormonedependent and HER2-positive metastatic breast cancer. Breast Cancer Res Treat Suppl 2006;100: abstract 3.
    • Mackey J, Kaufman B, Clemens M, et al. Trastuzumab prolongs progression-free survival in hormonedependent and HER2-positive metastatic breast cancer. Breast Cancer Res Treat Suppl 2006;100: abstract 3.
  • 38
    • 36849055007 scopus 로고    scopus 로고
    • Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: A phase I dose- escalation study
    • Modi S, Stopeck AT, Gordon MS, et al. Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: a phase I dose- escalation study. J Clin Oncol 2007;25:5410-7.
    • (2007) J Clin Oncol , vol.25 , pp. 5410-5417
    • Modi, S.1    Stopeck, A.T.2    Gordon, M.S.3


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