Influence of Exposure Intensity on the Efficiency and Speed of Transmission of Foot-and-Mouth Disease

Journal of Comparative Pathology

Volumn 140, Issue 4, 2009, Pages 225-237

  Quan, M ^a,b   Murphy, C M ^a   Zhang, Z ^a   Durand, S ^a   Esteves, I ^a   Doel, C ^a   Alexandersen, S ^c  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c CANADIAN FOOD INSPECTION AGENCY   (Canada)

Author keywords

foot and mouth disease; pig; sheep; transmission

Indexed keywords

AIRBORNE VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; DISEASE TRANSMISSION; EXPERIMENTAL STUDY; EXPOSURE; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; INCUBATION TIME; INFECTION RISK; INOCULATION; NONHUMAN; PRIORITY JOURNAL; SHEEP DISEASE; SWINE DISEASE; VIRUS STRAIN;

AIR MICROBIOLOGY; ANIMALS; CATTLE; CELLS, CULTURED; DISEASE TRANSMISSION, INFECTIOUS; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; HOUSING, ANIMAL; INHALATION EXPOSURE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX; SHEEP; SHEEP DISEASES; SPECIES SPECIFICITY; SWINE; SWINE DISEASES; THYROID GLAND; TIME FACTORS; VIRAL LOAD; VIREMIA;

ANIMALIA; FOOT-AND-MOUTH DISEASE VIRUS; FOOT-AND-MOUTH DISEASE VIRUS - TYPE O; OVIS ARIES; SUIDAE;

EID: 63549110216     PISSN: 00219975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcpa.2008.12.002     Document Type: Article

References (33)

1. Alexandersen S., and Donaldson A.I. Further Studies to Quantify the Dose of Natural Aerosols of Foot-and-Mouth Disease Virus for Pigs. Report of the Session of the Research Group of the Standing Technical Committee of the European Commission for the Control of Foot-and-Mouth Disease held at Island of Moen, Denmark, 12-15 September 2001 (2001), FAO, Rome Appendix 30, pp. 142-152
2. Alexandersen S., and Donaldson A.I. Further studies to quantify the dose of natural aerosols of foot-and-mouth disease virus for pigs. Epidemiology and Infection 128 (2002) 313-323
3. Alexandersen S., Brotherhood I., and Donaldson A.I. Natural aerosol transmission of foot-and-mouth disease virus to pigs: minimal infectious dose for strain O1 Lausanne. Epidemiology and Infection 128 (2002) 301-312
4. Alexandersen S., Zhang Z., Reid S.M., Hutchings G.H., and Donaldson A.I. Quantities of infectious virus and viral RNA recovered from sheep and cattle experimentally infected with foot-and-mouth disease virus O UK 2001. Journal of General Virology 83 (2002) 1915-1923
5. Alexandersen S., Kitching R.P., Mansley L.M., and Donaldson A.I. Clinical and laboratory investigations of five outbreaks of foot-and-mouth disease during the 2001 epidemic in the United Kingdom. Veterinary Record 152 (2003) 489-496
6. Alexandersen S., Quan M., Murphy C., Knight J., and Zhang Z. Studies of quantitative parameters of virus excretion and transmission in pigs and cattle experimentally infected with foot-and-mouth disease virus. Journal of Comparative Pathology 129 (2003) 268-282
7. Alexandersen S., Zhang Z., Donaldson A.I., and Garland A.J. The pathogenesis and diagnosis of foot-and-mouth disease. Journal of Comparative Pathology 129 (2003) 1-36
8. Alexandersen S., Oleksiewicz M.B., and Donaldson A.I. The early pathogenesis of foot-and-mouth disease in pigs infected by contact: a quantitative time-course study using TaqMan RT-PCR. Journal of General Virology 82 (2001) 747-755
9. Anderson R.M., and May R.M. Population biology of infectious diseases: part I. Nature 280 (1979) 361-367
10. Aramburu H.G. A comparison of different methods of inoculating guinea pigs with the virus of foot and mouth disease. Journal of Comparative Pathology 59 (1949) 42-47
11. Bedson S.P., Burbury M., and Maitland H.B. Susceptibility of Small Animals. B. Rats and Mice. First progress report of the Foot-and-Mouth Disease Research Committee (1925), H.M. Stationery Office, London pp. 36-39
12. Begon M., Bennett M., Bowers R.G., French N.P., Hazel S.M., and Turner J. A clarification of transmission terms in host-microparasite models: numbers, densities and areas. Epidemiology and Infection 129 (2002) 147-153
13. Bouma A., Dekker A., and de Jong M.C. No foot-and-mouth disease virus transmission between individually housed calves. Veterinary Microbiology 98 (2004) 29-36
14. Donaldson A.I., and Alexandersen S. Relative resistance of pigs to infection by natural aerosols of FMD virus. Veterinary Record 148 (2001) 600-602
15. Donaldson A.I., Alexandersen S., Sorensen J.H., and Mikkelsen T. Relative risks of the uncontrollable (airborne) spread of FMD by different species. Veterinary Record 148 (2001) 602-604
16. Ferris, N. P. (1987). Development and use of ELISA in the control of foot-and-mouth disease. IAEA Proceedings, 348, 65-77.
17. Ferris N.P., and Dawson M. Routine application of enzyme-linked immunosorbent assay in comparison with complement fixation for the diagnosis of foot-and-mouth and swine vesicular diseases. Veterinary Microbiology 16 (1988) 201-209
18. Hamblin C., Armstrong R.M., and Hedger R.S. A rapid enzyme-linked immunosorbent assay for the detection of FMDV in epithelial tissues. Veterinary Microbiology 9 (1984) 435-443
19. Hamblin C., Barnett I.T.R., and Hedger R.S. A new enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies against FMDV. 1. Development and method of ELISA. Journal of Immunological Methods 93 (1986) 115-121
20. Henderson W.M. A comparison of different routes of inoculation of cattle for detection of the virus of foot and mouth disease. Journal of Hygiene 50 (1952) 182-194
21. Howey, R., Quan, M., Savill, N. J., Matthews, L., Alexandersen, S. and Woolhouse, M. (2008). Effect of the initial dose of foot-and-mouth disease virus on the early viral dynamics within pigs. Journal of the Royal Society Interface. doi:10.1098/rsif.2008.0434.
22. Hughes G.J., Mioulet V., Haydon D.T., Kitching R.P., Donaldson A.I., and Woolhouse M.E.J. Serial passage of foot-and-mouth disease virus in sheep reveals declining levels of viraemia over time. Journal of General Virology 83 (2002) 1907-1914
23. Hughes G.J., Mioulet V., Kitching R.P., Woolhouse M.E.J., Alexandersen S., and Donaldson A.I. Foot-and-mouth disease virus infection of sheep: implications for diagnosis and control. Veterinary Record 150 (2002) 724-727
24. Kroese, A. H. and de Jong, M. C. M. (2001). Design and analysis of transmission experiments. In: Proceedings of a Meeting Held at the Golden Tulip Conference Centre, Leeuwenhorst, Noordwijkerhout, the Netherlands, March 2001, pp. 21-37.
25. Quan M., Murphy C.M., Zhang Z., and Alexandersen S. Determinants of early foot-and-mouth disease virus dynamics in pigs. Journal of Comparative Pathology 131 (2004) 294-307
26. Reid S., Ferris N., Hutchings G., Zhang Z., Belsham G., and Alexandersen S. Detection of all seven serotypes of foot-and-mouth disease virus by real-time, fluorogenic reverse transcription polymerase chain reaction assay. Journal of Virological Methods 105 (2002) 67-80
27. Reid S.M., Grierson S.S., Ferris N.P., Hutchings G.H., and Alexandersen S. Evaluation of automated RT-PCR to accelerate the laboratory diagnosis of foot-and-mouth disease virus. Journal of Virological Methods 107 (2003) 129-139
28. Roeder P.L., and Le Blanc Smith P.M. Detection and typing of FMDV by enzyme-linked immunosorbent assay: a sensitive, rapid and reliable technique for primary diagnosis. Research in Veterinary Science 43 (1987) 225-232
29. Snowdon W.A. Growth of FMDV in monolayer cultures of calf thyroid cells. Nature 210 (1966) 1079-1080
30. Zhang Z., and Alexandersen S. Detection of carrier cattle and sheep persistently infected with foot-and-mouth disease virus by a rapid real-time RT-PCR assay. Journal of Virological Methods 111 (2003) 95-100
31. Zhang Z., and Alexandersen S. Quantitative analysis of foot-and-mouth disease virus RNA loads in bovine tissues: implications for the site of viral persistence. Journal of General Virology 85 (2004) 2567-2575
32. Zhang Z., Murphy C., Quan M., Knight J., and Alexandersen S. Extent of reduction of foot-and-mouth disease virus RNA load in oesophageal-pharyngeal fluid after peak levels may be a critical determinant of virus persistence in infected cattle. Journal of General Virology 85 (2004) 415-421
33. Zhang Z.D., Hutching G., Kitching P., and Alexandersen S. The effects of gamma interferon on replication of foot-and-mouth disease virus in persistently infected bovine cells. Archives of Virology 147 (2002) 2157-2167