Bone Marrow Edema Syndrome in Postpartal Women: Treatment with Iloprost

Orthopedic Clinics of North America

Volumn 40, Issue 2, 2009, Pages 241-247

  Aigner, Nicholas ^a   Meizer, Roland ^a   Meraner, Dominik ^a   Becker, Stephan ^a   Meizer, Elizabeth ^a   Landsiedl, Franz ^a  

^a ORTHOPAEDIC HOSPITAL SPEISING   (Austria)

Author keywords

Bone marrow edema syndrome; Iloprost; Pregnancy; Therapy

Indexed keywords

ILOPROST; PARACETAMOL;

ADULT; ANALGESIA; BONE MARROW EDEMA SYNDROME; CLINICAL ARTICLE; CLINICAL ASSESSMENT; DRUG EFFECT; DRUG MECHANISM; DRUG WITHDRAWAL; FEMALE; FEMUR HEAD NECROSIS; FLUSHING; FOLLOW UP; FUNCTIONAL STATUS; HEADACHE; HIP PAIN; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PILOT STUDY; PREGNANT WOMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUERPERIUM; REVIEW; SIDE EFFECT; THROMBOCYTE AGGREGATION; TREATMENT DURATION; WEIGHT BEARING;

ADULT; ARTHRALGIA; BONE MARROW DISEASES; DIAGNOSIS, DIFFERENTIAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; FEMALE; FEMUR HEAD; FOLLOW-UP STUDIES; HIP JOINT; HUMANS; ILOPROST; INJECTIONS, INTRAVENOUS; MAGNETIC RESONANCE IMAGING; PILOT PROJECTS; POSTPARTUM PERIOD; PREGNANCY; PREGNANCY COMPLICATIONS; PROSPECTIVE STUDIES; RECOVERY OF FUNCTION; SYNDROME; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 63549092776     PISSN: 00305898     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ocl.2008.10.007     Document Type: Review

References (33)

1. Berger C.E., Kroner A.H., Minai-Pour M.B., et al. Biochemical markers of bone metabolism in bone marrow edema syndrome of the hip. Bone 33 (2003) 346-351
2. Glueck C.J., Freiberg R., Glueck H.I., et al. Hypofibrinolysis: a common, major cause of osteonecrosis. Am J Hematol 45 (1994) 156-166
3. Glueck C.J., Freiberg R., Glueck H.I., et al. Idiopathic osteonecrosis, hypofibrinolysis, high plasminogen activator inhibitor, high lipoprotein(a), and therapy with stanozolol. Am J Hematol 48 4 (1995) 213-220
4. Atsumi T., and Kuroki Y. Role of impairment of blood supply of the femoral head in the pathogenesis of idiopathic osteonecrosis. Clin Orthop 277 (1992) 22-30
5. Veldhuizen P.J., Neff J., Murphey M.D., et al. Decreased fibrinolytic potential in patients with idiopathic avascular necrosis and transient osteoporosis of the hip. Am J Hematol 44 (1993) 243-248
6. Hofmann S., Engel A., Neuhold A., et al. Bone marrow oedema syndrome and transient osteoporosis of the hip. J Bone Joint Surg Br 75-B (1993) 210-216
7. Jager M., Wild A., Krauspe R., et al. Osteonecrosis and HELLP-syndrome. Z Geburtshilfe Neonatol 207 (2003) 213-219
8. Genez B.M., Wilson M.R., Houk R.W., et al. Early osteonecrosis of the femoral head: detection in high-risk patients with MR-imaging. Radiology 168 (1988) 521-524
9. Boos S., Sigmund G., Huhle P., et al. MR of transient osteoporosis. Primary diagnosis and follow-up after treatment. Fortschr Roentgenstr 158 (1993) 201-206
10. Lakhanpal S., Ginsburg W.W., Luthra H.S., et al. Transient regional osteoporosis. A study of 56 cases and review of the literature. Ann Intern Med 106 (1987) 444-450
11. Aigner N., Eberl V., Schneider W., et al. Effect of core decompression in early stages of necrosis of the femoral head-an MRI-controlled study. Int Orthop 26 (2002) 31-35
12. Meizer R., Radda C., Stolz G., et al. MRI-controlled retrospective analysis of 104 patients with bone marrow edema of different localisations treated with Iloprost. Wien Klin Wochenschr 117 (2005) 278-286
13. Petje G., Radler C., Aigner N., et al. Aseptic osteonecrosis in childhood: diagnosis and treatment. Orthopade 31 (2002) 1027-1036
14. Aigner N., Petje G., Schneider W., et al. Bone marrow oedema syndrome of the femoral head: comparison of therapy with the prostacycline-analogue iloprost and core decompression. Wien Klin Wochenschr 117 (2005) 130-135
15. Grant S.M., and Goa K.L. Iloprost-a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in peripheral vascular disease, myocardial ischaemia and extracorporal circulation procedures. Drugs 43 (1992) 889-924
16. Curtiss Jr. P.H., and Kincaid W.E. Transitory demineralization of the hip in pregnancy: a report of three cases. J Bone Joint Surg Am 41-A (1959) 1327-1333
17. Kramer J., Hofmann S., Engel A., et al. Necrosis of the head of femur and bone marrow edema syndrome in pregnancy. Fortschr Roentgenstr 159 (1993) 126-131
18. Plenk Jr. H., Hofmann S., Eschberger J., et al. Histomorphology and bone morphometry of the bone marrow edema of the hip. Clin Orthop 334 (1997) 73-84
19. Funk J.L., Shoback D.M., Genant H.K., et al. Transient osteoporosis of the hip in pregnancy: natural history of changes in bone mineral density. Clin Endocrinol 43 (1995) 373-382
20. Hauzeur J.P., Perlmutter N., Appelboom T., et al. Medullary impairment at an early stage of non-traumatic osteonecrosis of the femoral head. Rheumatol Int 11 (1991) 215-217
21. Staudenherz A., Hofmann S., Breitenseher M., et al. Diagnostic patterns for bone marrow oedema syndrome and avascular necrosis of the femoral head in dynamic bone scintigraphy. Nucl Med Commun 18 (1997) 1178-1188
22. Froberg P.K., Braunstein E.M., Buckwalter K.A., et al. Osteonecrosis, transient osteoporosis, and transient bone marrow edema. Radiol Clin North Am 34 (1996) 273-291
23. Krause R., Glas K., Schulz A., et al. The transitory bone marrow edema syndrome of the hip. Z Orthop Ihre Grenzgeb 140 (2002) 286-296
24. Doury P. Bone marrow oedema, transient osteoporosis and algodystrophy. J Bone Joint Surg Br 76-B (1994) 993-994
25. Radke S., Kirschner S., Seipel V., et al. Treatment of transient bone marrow oedema of the hip-a comparative study. Int Orthop 27 3 (2003) 149-152
26. Radke S., Rader C., Kenn W., et al. Transient marrow edema syndrome of the hip: results after core decompression. A prospective MRI-controlled study in 22 patients. Arch Orthop Trauma Surg 123 5 (2003) 223-227
27. Hofmann S., Schneider W., Breitenseher M., et al. "Transient osteoporosis" as a special reversible form of femur head necrosis. Orthopade 29 5 (2000) 411-419
28. Rader C.P. Transient osteoporosis and osteonecrosis of the femoral head. Risk factors, classification and differential diagnosis. Orthopade 36 5 (2007) 423-429
29. Ringe J.D., Dorst A., Faber H., et al. Effective and rapid treatment of painful localized transient osteoporosis (bone marrow edema) with intravenous ibandronate. Osteoporos Int 16 12 (2005) 2063-2068
30. Carbone L.D., Nevitt M.C., Wildy K., et al. The relationship of antiresorbtive drug use to structural findings and symptoms of knee osteoarthritis. Arthritis Rheum 52 5 (2004) 1622-1623
31. Mayerhoefer M.E., Kramer J., Breitenseher M.J., et al. Short-term outcome of painful bone marrow oedema of the knee following oral treatment with iloprost or tramadol: results of an exploratory phase II study of 41 patients. Rheumatology (Oxford) 46 9 (2007) 1460-1465 [Epub 2007 Jul 17]
32. Sweeney A.T., Blake M., Holick M.F., et al. Transient osteoporosis of the hip in pregnancy. J Clin Densitom 3 (2000) 291-297
33. Uematsu N., Nakayama Y., Shirai Y., et al. Transient osteoporosis of the hip during pregnancy. J Nippon Med Sch 67 (2000) 459-463