Investigation of the adsorption mechanism of a peptide in reversed phase liquid chromatography, from pH controlled and uncontrolled solutions

Journal of Chromatography A

Volumn 1216, Issue 18, 2009, Pages 3992-4004

  Andrzejewska, Anna ^a,b   Gritti, Fabrice ^a,b   Guiochon, Georges ^a,b  

^a UNIVERSITY OF TENNESSEE   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

Acid base equilibrium adsorption mechanism; Retention of acido basic compounds RPLC; Tripeptides

Indexed keywords

ACID-BASE EQUILIBRIUM ADSORPTION MECHANISM; ADSORPTION MECHANISMS; AFFINITY ENERGY DISTRIBUTIONS; AQUEOUS SOLUTIONS; BI-LANGMUIR EQUATIONS; BONDED SILICAS; EQUILIBRIUM ADSORPTIONS; EQUILIBRIUM ISOTHERMS; FRONTAL ANALYSIS; HIGH EFFICIENCIES; INVERSE METHODS; ION-PAIRING AGENTS; ISOTHERM PARAMETERS; JUPITER; MOBILE PHASE; PACKING MATERIALS; PH CONDITIONS; RETENTION OF ACIDO-BASIC COMPOUNDS RPLC; REVERSED PHASE LIQUID CHROMATOGRAPHIES; TRIFLUOROACETIC ACIDS; TRIPEPTIDE; TRIPEPTIDES;

ACIDS; AMINES; AMINO ACIDS; ATMOSPHERIC TEMPERATURE; BIOCHEMISTRY; CHROMATOGRAPHIC ANALYSIS; INVERSE PROBLEMS; ISOTHERMS; LIQUID CHROMATOGRAPHY; METHANOL; PH; SILICA;

ADSORPTION;

LEUCYLLEUCYLLEUCINE; METHANOL; SILICON DIOXIDE; TRIFLUOROACETIC ACID; TRIPEPTIDE; UNCLASSIFIED DRUG;

ADSORPTION; ANALYTIC METHOD; AQUEOUS SOLUTION; ARTICLE; CALCULATION; FRONTAL ANALYSIS; ISOTHERM; MEASUREMENT; PARAMETER; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REVERSED PHASE LIQUID CHROMATOGRAPHY; TITRIMETRY;

ADSORPTION; CHROMATOGRAPHY, LIQUID; HYDROGEN-ION CONCENTRATION; PEPTIDES; SOLUTIONS;

EID: 63449131415     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.03.014     Document Type: Article

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