A new tool to assess the mechanical properties of bone due to collagen degradation

Bone

Volumn 44, Issue 5, 2009, Pages 840-848

  Wynnyckyj, C ^a,b   Omelon, S ^a   Savage, K ^a   Damani, M ^a   Chachra, D ^c   Grynpas, M D ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c FRANKLIN W OLIN COLLEGE OF ENGINEERING   (United States)

Author keywords

Bone collagen; Dual energy x ray absorptiometry (DXA); Mechanical properties; Mechanical response tissue analyzer (MRTA); Sex differences

Indexed keywords

POTASSIUM HYDROXIDE;

ANALYZER; ANIMAL TISSUE; ARTICLE; BONE; COLLAGEN DEGRADATION; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; MALE; MEASUREMENT; MECHANICAL RESPONSE TISSUE ANALYZER; NONHUMAN; SEX DIFFERENCE; TIBIA; TIBIA FRACTURE; ULTRASOUND;

ABSORPTIOMETRY, PHOTON; ANIMALS; BIOMECHANICS; BONE AND BONES; BONE DENSITY; COLLAGEN; DROMAIIDAE; FEMALE; HYDROXIDES; MALE; POTASSIUM COMPOUNDS; SEX FACTORS;

EID: 63449126814     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.12.014     Document Type: Article

References (64)

1. Boskey A. Bone mineralization. In: Cowin S.C. (Ed). Bone mechanics handbook (2001), CRC Press, Boca Raton, FL 1-33
2. Kaplan F.S., Hayes W.C., Keaveny T.M., Boskey A., Einhorn T.A., and Iannotti J.P. Form and Function of bone. In: Simon S.R. (Ed). Orthopaedic basic science (1994), American Academy of Orthopaedic Surgeons, Rosemont, IL 129-138
3. Burr D.B. The contribution of the organic matrix to bone's material properties. Bone 31 (2002) 8-11
4. Wang X., Shen X., Li X., and Agrawal C.M. Age-related changes in the collagen network and toughness of bone. Bone 31 (2002) 1-7
5. Wang X., Li X., Bank R.A., and Agrawal C.M. Effects of collagen unwinding and cleavage on the mechanical integrity of the collagen network in bone. Calcif. Tissue Int. 71 (2002) 186-192
6. Cefalu C.A. Is bone mineral density predictive of fracture risk reduction?. Curr. Med. Res. Opin. 20 (2004) 341-349
7. Cummings S.R., Karpf D.B., Harris F., Genant H.K., Ensrud K., LaCroix A.Z., and Black D.M. Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs. Am. J. Med. 112 (2002) 281-289
8. Genant H.K., Engelke K., Fuerst T Gluer C.C., Grampp S., Harris S.T., Jerqas M., Lang T., Lu Y., Majumdar S., Mathur A., and Takada M. Noninvasive assessment of bone mineral and structure: state of the art. J. Bone. Miner. Res. 11 (1996) 707-730
9. Djokoto C., Tomlinson G., Waldman S., Grynpas M., and Cheung A.M. Relationship among MRTA, DXA, and QUS. J. Clin. Densitom. 7 (2004) 448-456
10. Roberts S.G., Hutchinson T.M., Arnaud S.B., Kiratli B.J., Martin R.B., and Steele C.R. Noninvasive determination of bone mechanical properties using vibration response: a refined model and validation in vivo. J. Biomech. 29 (1996) 91-98
11. Norrdin R.W., Simske S.J., Gaarde S., Schwardt J.D., and Thrall M.A. Bone changes in mucopolysaccharidosis VI in cats and the effects of bone marrow transplantation: mechanical testing of long bones. Bone 17 (1995) 485-489
12. Hutchinson T.M., Bakulin A.V., Rakhmanov A.S., Martin R.B., Steele C.R., and Arnaud S.B. Effects of chair restraint on the strength of the tibia in rhesus monkeys. J. Med. Primatol. 30 (2001) 313-321
13. Myburgh K.H., Charette S., Zhou L., Steele C.R., Arnaud S., and Marcus R. Influence of recreational activity and muscle strength on ulnar bending stiffness in men. Med. Sci. Sports Exerc. 25 (1993) 592-596
14. Hutchinson T.M., Steele C.R., Snow-Harter R., Whalen R.T., Marcus R., and Arnaud S.B. Bending stiffness in the tibia of healthy men aged 26-51 years. Med. Sci. Sports Exerc. 26 (1994) S21
15. Smith S.R., Burshell J., Lindberg J., Bober M., and Davies M.J. Adaptation of bone in a kindred with osteogenesis imperfecta. J. Bone Miner. Res. 9 (1994) S424
16. Kiebzak G.M., Box J.H., and Box P. Decreased ulnar bending stiffness in osteoporotic Caucasian women. J. Clin. Densitom. 2 (1999) 143-152
17. McCabe F., Zhou L.J., Steele C.R., and Marcus R. Noninvasive assessment of ulnar bending stiffness in women. J. Bone Miner. Res. 6 (1991) 53-59
18. Maloney S.K., and Dawson T.J. Sexual dimorphism in basal metabolism and body temperature of a large bird, the emu. Condor 95 (1993) 1034-1037
19. Conzemius M.G., Brown T.D., Zhang Y., and Robinson R.A. A new animal model of femoral head osteonecrosis: one that progresses to human-like mechanical failure. J. Orthoptera Res. 20 (2002) 303-309
20. Reed K.L., and Brown T.D. Elastic modulus and strength of emu cortical bone. Iowa Orthop. J. 21 (2001) 53-57
21. Davies S.J.J.F. Ratites and tinamous (2002), Oxford University Press, New York
22. Reddy G.K., and Enwemeka C.S. A simplified method for the analysis of hydroxyproline in biological tissues. Clin. Biochem. 29 (1996) 225-229
23. Walsh B.J., Thornton S.C., Penny R., and Breit S.N. Microplate reader-based quantitation of collagens. Anal. Biochem. 203 (1992) 187-190
24. Vachon A.M., Keeley F.W., McIlwraith C.W., and Chapman P. Biochemical analysis of normal articular cartilage in horses. Am. J. Vet. Res. 51 (1990) 1905-1911
25. Sinha R.K., Shah S.A., Hume E.L., and Tuan R.S. The effect of a 5-day space flight on the immature rat spine. Spine J. 2 (2002) 239-243
26. Nyman J.S., Reyes M., and Wang X. Effect of ultrastructural changes on the toughness of bone. Micron 36 (2005) 566-582
27. Abe K., Hashizume H., and Ushiki T. An EDTA-KOH method to expose bone cells for scanning electron microscopy. J. Electron Microsc. 41 (1992) 113-115 (Tokyo)
28. Turner C.H., and Burr D.B. Basic biomechanical measurements of bone: a tutorial. Bone 14 (1993) 595-608
29. Jee W.S.S. Integrated bone tissue physiology. In: Cowin S.C. (Ed). Bone mechanics handbook (2001), CRC Press, Boca Raton, FL 1-68
30. Arsenault A.L. Vascular canals in bovine cortical bone studied by corrosion casting. Calcif. Tissue Int. 47 (1990) 320-325
31. Lin T.C., Su C.Y., and Chang C.S. Stereomorphologic observation of bone tissue response to hydroxyapatite using SEM with the EDTA-KOH method. J. Bone Miner. Res. 36 (1997) 91-97
32. Carter D.H., Scully A.J., Heaton D.A., Young M.P., and Aaron J.E. Effect of deproteination on bone mineral morphology: implications for biomaterials and aging. Bone 31 (2002) 389-395
33. Broz J.J., Simske S.J., Corley W.D., and Greenberg A.R. Effects of deproteinization and ashing on site-specific properties of cortical bone. J. Mater. Sci., Mater. Med. 8 (1997) 395-401
34. Ushiki T., and Chizuka I. Scanning electron microscopic studies of the myelinated nerve fibres of the mouse sciatic nerve with special reference to the Schwann cell cytoplasmic network external to the myelin sheath. J. Neurocytol. 16 (1987) 737-747
35. Miller B.G., Woods R.I., Bohlen H.G., and Evan A.P. A new morphological procedure for viewing microvessels: a scanning electron microscopic study of the vasculature of small intestine. Anat. Rec. 203 (1982) 493-503
36. Johnson G.S., Mucalo M.R., and Lorier M.A. The processing and characterization of animal-derived bone to yield materials with biomedical applications: part 1: modifiable porous implants from bovine condyle cancellous bone and characterization of bone materials as a function of processing. J. Mater. Sci., Mater. Med. 11 (2000) 427-441
37. Moreno E.C., Kresak M., and Hay D.I. Adsorption of molecules of biological interest onto hydroxyapatite. Calcif. Tissue Int. 36 (1984) 48-59
38. Jepsen K.J., Goldstein S.A., Kuhn J.L., Schaffler M.B., and Bonadio J. Type-I collagen mutation compromises the post-yield behavior of Mov13 long bone. J. Orthoptera Res. 14 (1996) 493-499
39. Oxlund H., Barckman M., Ortoft G., and Andreassen T.T. Reduced concentrations of collagen cross-links are associated with reduced strength of bone. Bone 17 (1995) 365S-371S
40. Turner C.H. Bone strength: current concepts. Ann. N. Y. Acad. Sci. 1068 (2006) 429-446
41. Jones R.M. Mechanics of composite materials (1999), Taylor & Francis, Philadelphia
42. Piekarski K. Analysis of bone as a composite material. Int. J. Eng. Sci 11 (1973) 557-565
43. Monette L., Anderson M.P., and Grest G.S. Effect of interphase modulus and cohesive energy on the critical aspect ratio in short-fibre composites. J. Mater. Sci. 28 (1993) 79-99
44. Bundy K.J. Determination of mineral-organic bonding effectiveness in bone-theoretical considerations. Ann. Biomed. Eng 13 (1985) 119-135
45. Bundy K.J. Composite material models for bone. In: Cowin S.C. (Ed). Bone mechanics (1989), CRC Press, Boca Raton, FL 197-208
46. Walsh W.R., and Guzelsu N. The role of ions and mineral-organic interfacial bonding on the compressive properties of cortical bone. Biomed. Mater. Eng. 3 (1993) 75-84
47. Walsh W.R., and Guzelsu N. Compressive properties of cortical bone: mineral-organic interfacial bonding. Biomaterials 15 (1994) 137-145
48. Walsh W.R., Ohno M., and Guzelsu N. Bone composite behaviour: effects of mineral-organic bonding. J. Mater. Sci., Mater. Med. 5 (1994) 72-79
49. Kotha S.P., Walsh W.R., Pan Y., and Guzelsu N. Varying the mechanical properties of bone tissue by changing the amount of its structurally effective bone mineral content. Biomed. Mater. Eng. 8 (1998) 321-334
50. DePaula C.A., Abjornson C., Pan Y., Kotha S.P., Koike K., and Guzelsu N. Changing the structurally effective mineral content of bone with in vitro fluoride treatment. J. Biomech. 35 (2002) 355-361
51. Kotha S.P., and Guzelsu N. The effects of interphase and bonding on the elastic modulus of bone: changes with age-related osteoporosis. Med. Eng. Phys. 22 (2000) 575-585
52. Pearce E.I. Ion displacement following the adsorption of anionic macromolecules on hydroxyapatite. Calcif. Tissue Int. 33 (1981) 395-402
53. Gupta H.S., Fratzl P., Kerschnitzki M., Benecke G., Wagermaier W., and Kirchner H.O. Evidence for an elementary process in bone plasticity with an activation enthalpy of 1 eV. J. R. Soc. Interface. 4 (2007) 277-282
54. Thompson J.B., Kindt J.H., Drake B., Hansma H.G., Morse D.E., and Hansma P.K. Bone indentation recovery time correlates with bond reforming time. Nature 414 (2001) 773-776
55. Fantner G.E., Hassenkam T., Kindt J.H., et al. Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture. Nat. Mater. 4 (2005) 612-616
56. Boskey A.L. Mineral-matrix interactions in bone and cartilage. Clin. Orthop. Relat. Res. (1992) 244-274
57. Tye C.E., Hunter G.K., and Goldberg H.A. Identification of the type I collagen-binding domain of bone sialoprotein and characterization of the mechanism of interaction. J. Biol. Chem. 280 (2005) 13487-13492
58. Walsh W.R., Labrador D.P., Kim H.D., and Guzelsu N. The effect of in vitro fluoride ion treatment on the ultrasonic properties of cortical bone. Ann. Biomed. Eng. 22 (1994) 404-415
59. Weiner S., and Wagner D. The material bone: structure-mechanical function relations. Annu. Rev. Mater. Sci. 28 (1998) 271-298
60. Seeman E., and Delmas P.D. Bone quality-the material and structural basis of bone strength and fragility. N. Engl. J. Med. 354 (2006) 2250-2261
61. Seeman E. Unresolved issues in osteoporosis in men. Rev. Endocr. Metab. Disord. 2 (2001) 45-64
62. Panagiotopoulos E., Kostopoulos V., Tsantzalis S., Fortis A.P., and Doulalas A. Impact energy absorption by specimens from the upper end of the human femur. Injury 36 (2005) 613-617
63. Zioupos P., Currey J.D., and Hamer A.J. The role of collagen in the declining mechanical properties of aging human cortical bone. J. Biomed. Mater. Res. 45 (1999) 108-116
64. Prevrhal S., Fuerst T., Fan B., et al. Quantitative ultrasound of the tibia depends on both cortical density and thickness. Osteoporos. Int. 12 (2001) 28-34