Immunohistochemical expression of glycodelin in breast cancer correlates with estrogen-receptor α and progesterone-receptor A positivity

Histology and Histopathology

Volumn 24, Issue 4, 2009, Pages 467-471

  Scholz, Christoph ^a   Toth, Bettina ^a   Barthell, Elisabeth ^a   Mylonas, Ioannis ^a   Weissenbacher, Tobias ^a   Friese, Klaus ^a   Jeschke, Udo ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Breast cancer; Differentiation; Glycodelin; Immunhistochemistry

Indexed keywords

ESTROGEN RECEPTOR ALPHA; PLACENTA PROTEIN 14; PROGESTERONE RECEPTOR A; GLYCOPROTEIN; PAEP PROTEIN, HUMAN; PLACENTA PROTEIN; PROGESTERONE RECEPTOR; TUMOR MARKER;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER GRADING; CANCER SURVIVAL; CELL DIFFERENTIATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOMETRIUM; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PROTEIN EXPRESSION; TUMOR DIFFERENTIATION; BIOSYNTHESIS; BREAST TUMOR; CANCER STAGING; DISEASE COURSE; LUNG CARCINOMA; METABOLISM; MIDDLE AGED; PAGET NIPPLE DISEASE; PATHOLOGY; PROGNOSIS;

AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, DUCTAL; CARCINOMA, LOBULAR; DISEASE PROGRESSION; ESTROGEN RECEPTOR ALPHA; FEMALE; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; PREGNANCY PROTEINS; PROGNOSIS; RECEPTORS, PROGESTERONE; TUMOR MARKERS, BIOLOGICAL;

EID: 63449121342     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Chiu P.C.N., Chung M.-K., Koistinen R., Koistinen H., Seppala M., Ho P.-C., Ng E.H.Y., Lee K.-F. and Yeung W.S.B. (2007). Cumulus oophorus-associated glycodelin-C displaces sperm-bound glycodelin-A and -F and stimulates spermatozoa-zona pellucida binding. J. Biol. Chem. 282, 5378-5388.
2. Elston C.W. and Ellis I.O. (2002). Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up, Histopathology 41, 154-161.
3. Goldhirsch A., Wood W. C., Gelber R.D., Coates A. S., Thurlimann B. and Senn H.J. (2007). Progress and promise: highlights of the international expert consensus on the primary therapy of early breast cancer 2007. Ann. Oncol. 18, 1133-1144.
4. Jeschke U., Wang X., Briese V., Friese K. and Stahn R. (2003). Glycodelin and amniotic fluid transferrin as inhibitors of E-selectin-mediated cell adhesion, Histochem. Cell Biol. 119, 345-354.
5. Jeschke U., Mylonas I., Kunert-Keil C., Dazert E., Shabani N., Werling M., Kuhn C., Janni W., Gerber B. and Friese K. (2005). Expression of glycodelin protein and mRNA in human ductal breast cancer carcinoma in situ, invasive ductal carcinomas, their lymph node and distant metastases, and ductal carcinomas with recurrence. Oncol. Rep. 13, 413-419.
6. Jeschke U., Kuhn C., Mylonas I., Schulze S., Friese K., Mayr D., Speer R., Briese, V., Richter D.U., Haase M. and Karsten U. (2006). Development and characterization of monoclonal antibodies for the immunohistochemical detection of glycodelin A in decidual, endometrial and gynaecological tumour tissues. Histopathology 48, 394-406.
7. Kamarainen M., Seppala M., Virtanen I. and Andersson L.C. (1997). Expression of glycodelin in MCF-7 breast cancer cells induces differentiation into organized acinar epithelium, Lab. Invest. 77, 565-573.
8. Kamarainen M., Halttunen M., Koistinen R., von Boguslawsky K., von Smitten K., Andersson L.C. and Seppala M. (1999). Expression of glycodelin in human breast and breast cancer. Int. J. Cancer 83, 738-742.
9. Mandelin E., Lassus H., Seppala M., Leminen A., Gustafsson J.A., Cheng G., Butzow R. and Koistinen R. (2003). Glycodelin in ovarian serous carcinoma: association with differentiation and survival. Cancer Res. 63, 6258-6264.
10. Morris H.R., Dell A., Easton R.L., Panico M., Koistinen H., Koistinen R., Oehninger S., Patankar M.S., Seppala M. and Clark G.F. (1996). Gender-specific glycosylation of human glycodelin affects its contraceptive activity. J. Biol. Chem. 271, 32159-32167.
11. Payne S.J., Bowen R.L., Jones J.L. and Wells C.A. (2008). Predictive markers in breast cancer - the present, Histopathology 52, 82-90.
12. Seppala M., Koistinen H., Koistinen R., Chiu P.C. and Yeung W.S. (2007). Glycosylation related actions of glycodelin: gamete, cumulus cell, immune cell and clinical associations, Hum. Reprod. Update 13, 275-287.
13. Seppala M., Taylor R.N., Koistinen H., Koistinen R. and Milgrom E. (2002). Glycodelin: a major lipocalin protein of the reproductive axis with diverse actions in cell recognition and differentiation. Endocr. Rev. 23, 401-430.
14. Stavreus-Evers A., Mandelin E., Koistinen R., Aghajanova L., Hovatta O. and Seppala M. (2006). Glycodelin is present in pinopodes of receptive-phase human endometrium and is associated with downregulation of progesterone receptor B. Fertil. Steril. 85, 1803-1811.
15. Tse J.Y., Chiu P.C., Lee K.F., Seppala M., Koistinen H., Koistinen R., Yao Y.Q. and Yeung W.S. (2002). The synthesis and fate of glycodelin in human ovary during folliculogenesis. Mol. Hum. Reprod. 8, 142-148.