Aromatase inhibitors prevent the estrogen rise associated with the flare effect of gonadotropins in patients treated with GnRH agonists

Fertility and Sterility

Volumn 91, Issue 4 SUPPL., 2009, Pages 1574-1577

  Bedaiwy, Mohamed A ^a   Mousa, Noha A ^b   Casper, Robert F ^c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b Institute of Medical Science   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; FOLLITROPIN; GONADOTROPIN; LETROZOLE; LEUPRORELIN; LUTEINIZING HORMONE; PROGESTERONE;

ADULT; ARTICLE; CLINICAL ARTICLE; DISEASE SEVERITY; DRUG EFFECT; ENDOMETRIOSIS; FEMALE; HORMONE BLOOD LEVEL; HUMAN; LEIOMYOMA; PRIORITY JOURNAL; SIDE EFFECT;

ADULT; AROMATASE INHIBITORS; ENDOMETRIOSIS; ESTROGENS; FEMALE; FOLLICLE STIMULATING HORMONE; GONADOTROPIN-RELEASING HORMONE; HUMANS; LEIOMYOMA; LEUPROLIDE; LUTEINIZING HORMONE; NITRILES; PROGESTERONE; TRIAZOLES;

EID: 63449109264     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.09.077     Document Type: Article

References (23)

1. Charbonnel B. [Analogs of gonadoliberin. Value in physiology and therapeutics]. Presse Med 23 (1994) 805-811 French
2. Perry C.M., and Brogden R.N. Goserelin: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in benign gynaecological disorders. Drugs 51 (1996) 319-346
3. Casper R.F. Clinical uses of gonadotropin-releasing hormone analogues. Can Med Assoc J 144 (1991) 153-158
4. Surrey E.S., Silverberg K.M., Surrey M.W., and Schoolcraft W.B. Effect of prolonged gonadotropin-releasing hormone agonist therapy on the outcome of in vitro fertilization-embryo transfer in patients with endometriosis. Fertil Steril 78 (2002) 699-704
5. Bozzini N., Messina M.L., Borsari R., Hilario S.G., and Pinotti J.A. Comparative study of different dosages of goserelin in size reduction of myomatous uteri. J Am Assoc Gynecol Laparosc 11 (2004) 462-463
6. Lethaby A.E., and Vollenhoven B.J. An evidence-based approach to hormonal therapies for premenopausal women with fibroids. Best Pract Res Clin Obstet Gynaecol 22 (2008) 307-331
7. Hansen K.A. Eyster KM. A review of current management of endometriosis in 2006: an evidence-based approach. S D Med 59 (2006) 153-159
8. 2(10)]LH-RH ethylamide. Fertil Steril 54 (1990) 227-232
9. Batzer F.R. GnRH analogs: Options for endometriosis-associated pain treatment. J Minim Invasive Gynecol 13 (2006) 539-545
10. Karaer O., Oruc S., and Koyuncu F.M. Aromatase inhibitors: possible future applications. Acta Obstet Gynecol Scand 83 (2004) 699-706
11. American Society for Reproductive. Revised American Society for Reproductive Medicine classification of endometriosis: 1996. Fertil Steril 67 (1997) 817-821
12. Schindler A.E., Buhler K., Gerhard I., Wiedemann R., Kimmig R., Schussler B., et al. [Treatment of endometriosis with the GnRH agonist leuprorelin acetate depot (Enatone-Gyn monthly depot): a multicenter study]. Zentralbl Gynakol 116 (1994) 679-686 German
13. Mitwally M.F., Gotlieb L., and Casper R.F. Prevention of bone loss and hypoestrogenic symptoms by estrogen and interrupted progestogen add-back in long-term GnRH-agonist down-regulated patients with endometriosis and premenstrual syndrome. Menopause 9 (2002) 236-241
14. Bedaiwy M.A., and Casper R.F. Treatment with leuprolide acetate and hormonal add-back for up to 10 years in stage IV endometriosis patients with chronic pelvic pain. Fertil Steril 86 (2006) 220-222
15. Saito S., Murakami T., Suzuki K., Terada Y., Fukushima K., and Moriya T. Intestinal endometriosis complicated by ileal perforation after initiation of gonadotropin-releasing hormone agonist therapy. Fertil Steril 88 (2007) 969.e7-9
16. Hall L.L.H., Malone J.M., and Ginsburg K.A. Flare-up of endometriosis induced by gonadotropin-releasing hormone agonist leading to bowel obstruction. Fertil Steril 64 (1995) 1204-1206
17. Basu M., and Ahmed A.I.H. Goserelin administration causing an acute abdomen in a patient with a fibroid uterus. J Obstet Gynaecol 27 (2007) 90-91
18. Friedman A.J., Juneau-Norcross M., and Rein M.S. Adverse effects of leuprolide acetate depot treatment. Fertil Steril 59 (1993) 448-450
19. Yu K.-J., Lai C.-R., and Sheu M.-H. Spontaneous expulsion of a uterine submucosal leiomyoma after administration of a gonadotropin-releasing hormone agonist. Eur J Obstet Gynecol Reprod Biol 96 (2001) 223-225
20. Biljan M.M., Mahutte N.G., Dean N., Hemmings R., Bissonnette F., and Tan S.L. Pretreatment with an oral contraceptive is effective in reducing the incidence of functional ovarian cyst formation during pituitary suppression by gonadotropin-releasing hormone analogues. J Assisted Reprod Genet 15 (1998) 599-604
21. Engmann L., Maconochie N., Bekir J., and Tan S.L. Progestogen therapy during pituitary desensitization with gonadotropin-releasing hormone agonist prevents functional ovarian cyst formation: a prospective, randomized study. Am J Obstet Gynecol 181 (1999) 576-582
22. Cedrin-Durnerin I., Bulwa S., Herve F., Martin-Pont B., Uzan M., and Hugues J.N. The hormonal flare-up following gonadotrophin-releasing hormone agonist administration is influenced by a progestogen pretreatment. Hum Reprod 11 (1996) 1859-1863
23. Kimura F., Takahashi K., Takebayashi K., Fujiwara M., Kita N., Noda Y., et al. Concomitant treatment of severe uterine adenomyosis in a premenopausal woman with an aromatase inhibitor and a gonadotropin-releasing hormone agonist. Fertil Steril 87 (2007) 1468.e9-12