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Volumn 877, Issue 11-12, 2009, Pages 1040-1046
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Development of a sensitive and selective LC-MS/MS method for the determination of α-fluoro-β-alanine, 5-fluorouracil and capecitabine in human plasma
a
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Author keywords
Fluoro alanine (FBAL); 5 Fluorouracil (5 FU); Capecitabine; Dansyl chloride; Derivatization; Mass spectrometry
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Indexed keywords
5-FLUOROURACIL;
5-FLUOROURACIL (5-FU);
ANALYTICAL COLUMNS;
AQUEOUS PHASE;
C18 STATIONARY PHASE COLUMNS;
CAPECITABINE;
CONCENTRATION RANGES;
DANSYL CHLORIDE;
DERIVATIZATION;
ETHYL ACETATES;
HUMAN PLASMAS;
ION PAIRINGS;
LC-MS/MS;
LIQUID-LIQUID EXTRACTIONS;
METHYL TERTIARY-BUTYL ETHERS;
PHARMACOKINETIC STUDIES;
QUANTITATIVE METHODS;
REVERSED-PHASE;
SOLID-PHASE EXTRACTIONS;
ACETONITRILE;
CHEMICAL REACTIONS;
CHLORINE COMPOUNDS;
CHROMATOGRAPHIC ANALYSIS;
COLUMN CHROMATOGRAPHY;
ESTERS;
ETHERS;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
LIQUIDS;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
PARTICLE SIZE ANALYSIS;
PLASMA (HUMAN);
PLASMAS;
PURIFICATION;
SOLVENT EXTRACTION;
SPECTRUM ANALYSIS;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
ACETIC ACID ETHYL ESTER;
ACETONITRILE;
ALPHA FLUORO BETA ALANINE;
CAPECITABINE;
DANSYL CHLORIDE;
FLUOROURACIL;
TERT BUTYL METHYL ETHER;
ACCURACY;
ANALYTIC METHOD;
ARTICLE;
BLOOD ANALYSIS;
CONCENTRATION RESPONSE;
DERIVATIZATION;
DRUG DETERMINATION;
DRUG ISOLATION;
HUMAN;
LIQUID CHROMATOGRAPHY;
LIQUID LIQUID EXTRACTION;
MASS SPECTROMETRY;
PRIORITY JOURNAL;
QUANTITATIVE ASSAY;
REVERSED PHASE LIQUID CHROMATOGRAPHY;
SENSITIVITY AND SPECIFICITY;
SOLID PHASE EXTRACTION;
TECHNIQUE;
ULTRA HIGH PRESSURE LIQUID CHROMATOGRAPHY;
VALIDITY;
ANTIMETABOLITES, ANTINEOPLASTIC;
BETA-ALANINE;
DANSYL COMPOUNDS;
DEOXYCYTIDINE;
FLUOROURACIL;
HUMANS;
INDICATORS AND REAGENTS;
MASS SPECTROMETRY;
METHYL ETHERS;
QUALITY CONTROL;
REFERENCE STANDARDS;
REPRODUCIBILITY OF RESULTS;
SPECIMEN HANDLING;
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EID: 63449108196
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2009.02.025 Document Type: Article |
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Times cited : (63)
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References (17)
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