Comparative efficacy and safety of oxcarbazepine versus divalproex sodium in the treatment of acute mania: A pilot study

European Psychiatry

Volumn 24, Issue 3, 2009, Pages 178-182

  Kakkar, Ashish Kumar ^a   Rehan, H S ^a   Unni, K E S ^a   Gupta, Neeraj Kumar ^a   Chopra, Deepti ^a   Kataria, Dinesh ^a  

^a LADY HARDINGE MEDICAL COLLEGE   (India)

Author keywords

Acute mania; Divalproex; Oxcarbazepine

Indexed keywords

LORAZEPAM; OXCARBAZEPINE; VALPROATE SEMISODIUM;

ABDOMINAL PAIN; ACUTE DISEASE; ADULT; AGITATION; ALOPECIA; APPETITE; ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIARRHEA; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; DYSPEPSIA; EPISTAXIS; FEMALE; HEADACHE; HOSTILITY; HUMAN; INSOMNIA; IRRITABILITY; MAJOR CLINICAL STUDY; MALE; MANIA; NAUSEA AND VOMITING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH; RECURRENT DISEASE; REMISSION; RESTLESSNESS; SEDATION; SIDE EFFECT; THROMBOCYTOPENIA; TREATMENT RESPONSE; WEIGHT GAIN; XEROSTOMIA; YOUNG MANIA RATING SCALE;

ACUTE DISEASE; ADULT; ANTICONVULSANTS; ANTIMANIC AGENTS; BIPOLAR DISORDER; CARBAMAZEPINE; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; PILOT PROJECTS; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME; VALPROIC ACID;

EID: 63449106505     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpsy.2008.12.014     Document Type: Article

References (19)

1. Bowden C.L., and Singh V. Valproate in bipolar disorder: 2000 onwards. Acta Psychiatr Scand 111 (2005) S13-S20
2. Cabrera J.F., Muhlbauer H.D., Schley J., Stoll K.D., and Muller-Oerlinghausen B. Long-term randomized clinical trial of oxcarbazepine vs. lithium in bipolar and schizoaffective disorder: preliminary results. Pharmacopsychiatry 19 (1986) 282-283
3. Emrich H.M. Studies with oxcarbazepine (Trileptal) in acute mania. Int Clin Psychopharmacol 5 (1990) 83-88
4. Emrich H.M., Altman H., Dose M., and Von Zerssen D. Therapeutic effects of GABA-ergic drugs in affective disorder. A preliminary report. Pharmacol Biochem Behav 19 (1983) 369-372
5. Emrich H.M., Dose M., and Von Zerssen D. The use of sodium valproate, carbamazepine, and oxcarbazepine in patients with affective disorders. J Affect Disord 8 (1985) 243-250
6. Ghaemi S.N., Berv D.A., Klugman J., Rosenquist K.J., and Hsu D.J. Oxcarbazepine treatment of bipolar disorder. J Clin Psychiatry 64 (2003) 943-945
7. In: Goodwin F.K., and Jamison K.R. (Eds). Manic-depressive illness (1990), Oxford University Press, New York
8. Maj M., Pirozzi R., and Kemali D. Long term outcome of lithium prophylaxis in patients initially classified as complete responders. Psychopharmacology 98 (1989) 535-538
9. Müller A.A., and Stoll K.D. Carbamazepine and oxcarbazepine in the treatment of manic syndromes: studies in Germany. In: Emrich H.M., Okuma T., and Müller A.A. (Eds). Anticonvulsants in affective disorders (1984), Excerpta Medica, Amsterdam 139-147
10. Naranjo C.A., Busto U., Sellers E.M., Sandor P., Ruiz I., Roberts E.A., et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 30 (1981) 239-245
11. Nasr S. Oxcarbazepine for mood disorders. Am J Psychiatry 159 (2002) 1793
12. Pope H.G., McElroy S.L., Keck P.E., and Hudson J.I. Valproate in the treatment of acute mania. A placebo-controlled study. Arch Gen Psychiatry 48 (1991) 62-68
13. Post R.M., and Altshuler L.L. Mood disorders: treatment of bipolar disorders. In: Sadock B.J., and Sadock V.A. (Eds). Kaplan and Sadock's comprehensive textbook of psychiatry. 8th ed. (2005), Lippincott William and Wilkins, Philadelphia, USA 1661-1707
14. Reinstein M.J., Sonnenberg J.G., Hedberg T.G., Jones L.E., and Reyngold P. Oxcarbazepine versus divalproex sodium for the continuing treatment of mania. Clin Drug Invest 23 (2003) 671-677
15. Tohen M., Ketter T.A., Zarate C.A., Suppes T., Frye M., Altshuler L., et al. Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study. Am J Psychiatry 160 (2003) 1263-1271
16. Velikonja M.H.K. Effect of oxcarbazepine (GP 47.680) on affective and schizoaffective symptoms: a preliminary report. In: Okuma T., Emrich H.M., and Muller A.A. (Eds). Anticonvulsants in affective disorders (1984), Excerpta Medica, Amsterdam 208-210
17. Weissman M.M., Bland R.C., Canino G.J., Faravelli C., Greenwald S., and Hwu H.G. Crossnational epidemiology of major depression and bipolar disorder. JAMA 276 (1996) 293-299
18. Yatham L.N. Newer anticonvulsants in the treatment of bipolar disorder. J Clin Psychiatry 65 (2004) S28-S35
19. Young R.C., Biggs J.J., Zeigler V.E., and Meyer D.A. A rating scale for mania - reliability, validity and sensitivity. Br J Psychiatry 133 (1978) 429-435