Three genetic developmental stages of papillary renal cell tumors: Duplication of chromosome 1q marks fatal progression

International Journal of Cancer

Volumn 124, Issue 9, 2009, Pages 2071-2076

  Szponar, Adrianna ^a   Zubakov, Dmitry ^a,b   Pawlak, Justyna ^a   Jauch, Anna ^a   Kovacs, Gyula ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Array CGH; Chromosome 1q gain; Gene expression; Papillary renal cell tumor; Tumor progression

Indexed keywords

ARTICLE; CANCER CLASSIFICATION; CANCER GROWTH; CANCER SIZE; CANCER SURVIVAL; CHROMOSOME 12Q; CHROMOSOME 14Q; CHROMOSOME 16Q; CHROMOSOME 17; CHROMOSOME 1P; CHROMOSOME 1Q; CHROMOSOME 20Q; CHROMOSOME 3Q; CHROMOSOME 6Q; CHROMOSOME 8P; CHROMOSOME 8Q; CHROMOSOME 9P; CHROMOSOME DELETION; CHROMOSOME DUPLICATION; CHROMOSOME LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; KARYOTYPING; KIDNEY CARCINOMA; KIDNEY PAPILLA; KIDNEY PAPILLA TUMOR; KIDNEY TUMOR; MALE; PRIORITY JOURNAL; TRISOMY; TRISOMY 12; TRISOMY 16; TRISOMY 7; BACTERIAL ARTIFICIAL CHROMOSOME; CANCER STAGING; CHROMOSOME 1; CHROMOSOME MAP; CLASSIFICATION; COMPARATIVE GENOMIC HYBRIDIZATION; DISEASE COURSE; DNA MICROARRAY; GENE DOSAGE; GENE DUPLICATION; GENE EXPRESSION PROFILING; GENETIC MARKER; GENETICS; METABOLISM; PAPILLARY CARCINOMA; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; TREATMENT OUTCOME;

KIF14 PROTEIN, HUMAN; KINESIN; MESSENGER RNA; NEK2 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE;

CARCINOMA, PAPILLARY; CHROMOSOME DELETION; CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CHROMOSOMES, HUMAN, PAIR 1; COMPARATIVE GENOMIC HYBRIDIZATION; DISEASE PROGRESSION; FEMALE; GENE DOSAGE; GENE DUPLICATION; GENE EXPRESSION PROFILING; GENETIC MARKERS; HUMANS; KARYOTYPING; KIDNEY NEOPLASMS; KINESIN; MALE; NEOPLASM STAGING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENE PROTEINS; PROGNOSIS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SURVIVAL RATE; TREATMENT OUTCOME; TRISOMY;

EID: 63449087666     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24180     Document Type: Article

References (33)

1. Kovacs G, Kovacs A. Parenchymal abnormalities associated with papillary renal cell tumors. J Urol Path 1993;1:301-312
2. Ornstein DK, Lubensky IA, Venzon D, Zbar B, Linehan WM, Walther MM. Prevalence of microscopic tumors in normal appearing renal parenchyma of patients with hereditary papillary renal cancer. J Urol 2000;163:431-433 (Pubitemid 30060486)
3. Apitz K. Die Geschw€ulste und Gewebsmissbildungen der Nierenrinde. Die Adenome Virchows Arch 1944;311:328-359
4. Mancialla-Jimenez R, Stanley RJ, Blath RA. Papillary renal cell carcinoma: a clinical, radiologic and pathologic study of 34 cases. Cancer 1976;38:2469-2480 (Pubitemid 8015883)
5. Amin MB, Corless CL, Renshaw AA, Tickoo SK, Kubus J, Schultz DS. Papillary (chromophil) renal cell carcinoma: histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 62 cases. Am J Surg Pathol 1997;21:621-635 (Pubitemid 27265749)
6. Kovacs G. Papillary renal carcinoma: a morphologic and cytogenetic study of 11 cases. Am J Pathol 1989;134:27-34. (Pubitemid 19054975)
7. Kovacs G, Füzesi L, Emanuel A, Kung H. Cytogenetics of papillary renal cell tumors. Genes Chromosomes Cancer 1991;3:249-255
8. Palmedo G, Fischer J, Kovacs G. Fluorescent microsatellite analysis reveals duplication of specific chromosomal regions in papillary renal cell tumors. Lab Invest 1997;77:633-638 (Pubitemid 28018784)
9. Balint I, Fischer J, Ljungberg B, Kovacs G. Mapping the papillary renal cell carcinoma gene between loci D17S787 and D17S1799 on chromosome 17q21.32. Lab Invest 1999;79:1713-1718 (Pubitemid 30013934)
10. Kovacs G. Molecular differential pathology of renal cell tumors: a review. Histopathology 1993;22:1-8. (Pubitemid 23043987)
11. Kovacs G. Molecular cytogenetics of renal cell tumors. Adv Cancer Res 1993;62:89-124. (Pubitemid 23361850)
12. Fischer J, Palmedo G, von Knobloch R, Bugert P, Prayer-Galetti T, Pagano F, Kovacs G. Duplication and overexpression of the mutant allele of the MET proto-oncogene in multiple hereditary papillary renal cell tumors. Oncogene 1998;17:733-739 (Pubitemid 28412494)
13. Kovacs G, Akhtar M, Beckwith B, Bugert P, Cooper CS, Delahunt B, Eble JN, Fleming S, Ljungberg B, Medeiros LJ, Moch H, Reuter VE, et al. The Heidelberg classification of renal cell tumors. J Pathol 1997;183:131-133
14. Lichter P, Cremer T. Chromosome analysis by non-isotopic in situ hybridization. In: Rooney DE, Czepulkowski BH, eds. Human cytogenetics - a practical approach. Oxford: IRL-Press, 1992.157-92
15. du Manoir S, Speicher MR, Joos S, Schrock E, Popp S, Dohner H, Kovacs G, Robert-Nicoud M, Lichter P, Cremer T. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization. Hum Genet 1993;90:590-610.
16. Vissers LELM, de Vries BBA, Osoegawa K, Janssen IM, Feuth T, Choy CO, Straatman H, van der Vliet W, Huys EHLPG, van Rijk A, Smeets D, van Ravenswaaij-Arts CMA, et al. Array based comparative genomic hybridization for the genomewide detection of submicroscopic chromosomal abnormalities. Am J Hum Genet 2003;73:1261-1270
17. de Vries BBA, Pfundt R, Leisink M, Koolen AD, Vissers LELM, Janssen IM, van Reijmersdal S, Nillesen WM, Huys EHLPG, de Leeuw N, Smeets D, Sistermans EA et al. Diagnostic genome profiling in mental retardation. Am J Hum Genet 2005;77:606-616,
18. Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 2003;31:e15.
19. Subramanian A, Tamayo P, Vamsi K, Mootha VK, Mukherjeed S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Landera ES, Mesirova JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005;102:15545-15550 (Pubitemid 41528093)
20. Cruciger QV, Pathak S, Cailleau R. Human breast carcinomas: marker chromosomes involving 1q in seven cases. Cytogenet Cell Genet 1976;17:231-235
21. Atkin MB, Pickthall VJ. Chromosomes 1 in 14 ovarian cancers. Hum Genet 1977;38:25-33.
22. Kovacs G. Abnormalities of chromosome no.1 in human solid malignant tumors. Int J Cancer 1978;15:688-694
23. Gahrton G, Friberg K, Zech L, Lindstein J. Duplication of part of chromosome No.1 in myeloproliferative diseases. Lancet 1978;1:96-97.
24. Sawyer JR, Husain M, Al-Mefty O. Identification of isochromosome 1q as a recurring chromosome aberration in skull base chordomas: a new marker for aggressive tumors? Neurosurg Focus 2001;10:e6.
25. Nishimura T, Nishida N, Itoh T, Komeda T, Fukuda Y, Ikai I, Yamaoka Y, Nakao K. Discrete breakpoint mapping and shortest region of overlap of chromosome arm 1q gain and 1p loss in human hepatocellular carcinoma detected by semiquantitative microsatellite analysis. Genes Chromosomes Cancer 2005;42:34-43. (Pubitemid 39578663)
26. Mendrzyk F, Korshunov A, Benner A, Toedt G, Pfister S, Radlwimmer B, Lichter P. Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymoma. Clin Cancer Res 2006;12:2070-2079
27. Corson TW, Huang A, Tsao MS, Gallie BL. KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers. Oncogene 2005;24:4741-4753 (Pubitemid 41076292)
28. Hing S, Lu YL, Summersgill B, King-Underwood L, Nicholson J, Grundy P, Grundy R, Gessler M, Shipley J, Pritchard-Jones K. Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors. Am J Pathol 2001;158:393-398 (Pubitemid 32158602)
29. Natrajan R, Williams RD, Hing SN, Mackay A, Reis-Filho JS, Fenwick K, Irvani M, Valgeirsson H, Grigoriadis A, Langford CF, Dovey O, Gregory SG, et al. Array CGH profiling of favorable histology Wilms tumors reveals novel gains and losses associated with relapse. J Pathol 2006;210:49-58.
30. Gunawan B, von Heydebreck A, Fritsch T, Huber W, Ringert RH, Jakse G, F€uzesi L. Cytogenetic and morphologic typing of 58 papillary renal cell carcinomas: evidence for a cytogenetic evolution of type 2 from type 1 tumors. Cancer Res 2003;63:6200-6205 (Pubitemid 37255164)
31. Delahunt B, Eble JN. Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. Mod Pathol 1997;10:537-544 (Pubitemid 27293491)
32. Beckwith JB, Kiviat NB, Bonadio JF. Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor. Pediatr Pathol 1990;10:1-36. (Pubitemid 20130951)
33. Kaneko Y, Homma C, Maseki N, Sakurai M, Hata J. Correlation of chromosome abnormalities with histological and clinical feature in Wilms' and other childhood renal tumors. Cancer Res 1991;51:5937-5942