A cell membrane modification technique using domain 4 of intermedilysin for immunotherapy against cancer

Anticancer Research

Volumn 24, Issue 5 C, 2004, Pages 3367-3372

  Nagamune, Hideaki ^a   Ohkura, Kazuto ^b   Umezu, Kazunori ^c   Shouji, Hidekatsu ^c   Kourai, Hiroki ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Immunotherapy; Intermedilysin; Membrane; Modification

Indexed keywords

CARCINOEMBRYONIC ANTIBODY; CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY; CYTOLYSIN; IMMUNOGLOBULIN F(AB')2 FRAGMENT; INTERMEDILYSIN; STREPTOLYSIN O; UNCLASSIFIED DRUG;

CANCER IMMUNOLOGY; CANCER IMMUNOTHERAPY; CONFERENCE PAPER; HUMAN; HUMAN CELL; MEMBRANE BINDING; MEMBRANE STRUCTURE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ANIMALS; ANTIBODIES, MONOCLONAL; BACTERIAL PROTEINS; BACTERIOCINS; CARCINOEMBRYONIC ANTIGEN; CARCINOMA, MEDULLARY; CELL LINE, TUMOR; CELL MEMBRANE; CYTOTOXINS; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; HUMANS; IMMUNOCONJUGATES; IMMUNOGLOBULIN FRAGMENTS; IMMUNOTHERAPY; PROTEIN STRUCTURE, TERTIARY; RABBITS; RECOMBINANT PROTEINS; THYROID NEOPLASMS;

EID: 6344291415     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (20)

1. Kuroki M, Shibaguchi H, Imakiire T, Uno K, Shirota K, Higuchi T, Shitama T, Yamada H, Hirose Y, Nagata A and Kuroki M: Immunotherapy and gene therapy of cancer using antibodies or their genes against tumor-associated antigens. Anticancer Res 23: 4377-4382, 2003.
2. Haifa C, Gafner V, Villani ME, Borsi L, Berndt A, Kosmehl H, Zardi L and Neri D: Synergistic therapeutic effects of tumor targeting antibody fragment, fused to interleukein 12 and to tumor necrosis factor a. Cancer Res 63: 3202-3210, 2003.
3. Wüest T, Moosmayer D and Pfizenmajer K: Construction of a bispecific single chain antibody to recruitment of cytotoxic T cells to the tumor stroma associated antigen fibroblast activation protein. J Biotechnol 92: 159-168, 2001.
4. Yee C, Thompson JA, Byrd D, Riddell SR, Roche E, Celis E and Greenberg PD: Adoptive T cell therapy using antigen-specific CDS+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells. Proc Natl Acad Sci USA 99: 16168-16173, 2002.
5. Chang AE, Geiger JD, Sondak VK and Shu S: Adoptive cellular therapy of malignancy. Arch Surg 128: 1281-1290, 1993.
6. Lodge PA, Jones LA, Bader RA, Murphy GP and Salgaller ML: Dendritic cell-based immunotherapy of prostate cancer: immune monitoring of a phase II clinical trial. Cancer Res 60: 329-833, 2000.
7. Hagenaars M, Ensink NG, Jonges LE, Chambers WH, Eggermont AM, van de Velde CJ, Fleuren GJ and Kuppen PJ: The development of a bi-specific anti-CD161A x anti-tumor antibody for rat NK cell targeting. Immunobiol 200: 31-48, 1999.
8. Suzuki S, Watanabe S, Masuko T and Hashimoto Y: Preparation of long-circulating immunoliposomes containing adriamycin by a novel method to coat immunoliposomes with poly (ethylene glycol). Biochim Biophys Acta 1245: 9-16, 1995.
9. Hosokawa S, Tagawa T, Niki H, Hirakawa Y, Nohga K and Nagaike K: Efficacy of immunoliposomes on cancer models in a cell-surface-antigen-density-dependent manner. Br J Cancer 89: 1545-1551, 2003.
10. Rossjohn J, Tweten RK, Rood JI and Parker MW: Perfringolysin O: In: The Comprehensive Sourcebook of Bacterial Protein Toxins (Alouf JE and Freer JH, eds). London, Academic Press 1999, pp496-510.
11. Baba H, Kawamura I, Kohda C, Nomura T, Ito Y, Kimoto T, Watanabe I, Ichiyama S and Mitsuyama M: Essential role of domain 4 of pneumolysin from Streptococcus pneumoniae in cytolytic activity as detemined by truncated proteins. Biochem Biophys Res Commun 281: 37-44, 2001.
12. Weis S and Palmer M: Streptolysin O: the C-terminal, tryptophan-rich domain carries functional sites for both membrane binding and self-interaction but not for stable oligomerization. Biochim Biophys Acta 1510: 292-299, 2001.
13. Nagamune H, Ohnishi C, Katsuura A, Fushitani K, Whiley RA, Tsuji A and Matsuda Y: Intermedilysin, a novel cytotoxin specific for human cells, secreted by Streptococcus intermedius UNS46 isolated from a human liver abscess. Infect Immun 64: 3093-3100, 1996.
14. Nagamune H, Goto T, Whiley RA, Maeda T, Inai Y, Ohnishi O, Ohkura K, Hardie JM and Kourai H: Structural and epidemiological characterization of a human-specific cytolysin, intermedilysin: a potentially significant virulence factor in Streptococcus intermedius infections. In: Streptococci and Streptococcal Diseases (Martin DR, and Tagg JR, eds). Wellington, Securacopy 2000, pp.737-740.
15. Nagamune H, Whiley RA, Goto T, Inai Y, Maeda T, Hardie JM and Kourai H: Distribution of the intermedilysin gene among the anginosus group streptococci and correlation between intermedilysin production and deep-seated infection with Streptococcus intermedius. J Clin Microbiol 38: 220-226, 2000.
16. Leong SS, Horoszewicz JS, Shimaoka K, Friedman M, Kawinski E, Song MJ, Zeigel R, Chu TM, Baylin S and Mirand EA: A new cell line for study of human medullary thyroid carcinoma. In: Advances in Thyroid Neoplasia (Andreoli M, Monaco F and Robbins J, eds). Rome, Field Educational Italia 1981, pp95-108.
17. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
18. Nagamune H, Muramatsu K, Akamatsu T, Tamai Y, Izumi K, Tsuji A and Matsuda Y: Distribution of kexin like proteases in pancreatic islets: PACE4C is specifically expressed in B cells of pancreatic islets. Endocrinol 136: 357-360, 1995.
19. Macey MG, Whiley RA, Miller L and Nagamune H: Effect on polymorphonuclear cell function of human-specific cytotoxin, intermedilysin, expressed by Streptococcus intermedius. Infect Immun 69: 6102-6109, 2001.
20. Nagamure H, Ohkura K, Sukeno A, Cowan G, Mitcheu TJ, Ito W, Ohnishi O, Hattori K, Yamoto M, Hirota K, Miyake Y, Maeda T and Kourai H: The human-specific action of intermedilysin, a homolog of Streptolysin ©, is dictated by domain 4 of the protein. Microbiol Immunol 48: in press, 2004.