Why zygosity of multiple births is not always obvious: An examination of zygosity testing requests from twins or their parents

Twin Research

Volumn 7, Issue 5, 2004, Pages 406-411

  Bamforth, Fiona ^a,c   Machin, Geoffrey ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b KAISER PERMANENTE MEDICAL CENTER   (United States)

^c UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; DIZYGOTIC TWINS; FEMALE; GENETIC ANALYSIS; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MULTIPLE PREGNANCY; NEWBORN; PARENT; PARENTAL NOTIFICATION; PHENOTYPE; PRIORITY JOURNAL; SIBLING; TWINS; ZYGOSITY;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MULTIPLE BIRTH OFFSPRING; PARENTS; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 6344269563     PISSN: 13690523     EISSN: None     Source Type: Journal    
DOI: 10.1375/1369052042335287     Document Type: Article

References (23)

1. Bamforth, F. (1999). How to test twins for zygosity. (1999). In G. Machin & K. Louis (Eds.), An atlas of multiple pregnancy (pp. 61-63). New York: Parthenon.
2. Bamforth, F., Brown, L., Senz, J., & Huntsman, J. (2003). Mechanisms of monozygotic (MZ) twinning: A possible role for the cell adhesion molecule, E-cadherin. American Journal of Medical Genetics, 120A, 59-62.
3. Bamforth, F., & Machin, G. (1994). Non-medical reasons for requesting zygosity testing. American Journal of Medical Genetics, 55, A306 (abstract).
4. Bamforth, F., Machin, G., & Innes, M. (1996). X-chromosome inactivation is mostly random in placental tissues of female monozygotic twins and triplets. American Journal of Medical Genetics, 61, 209-215.
5. Eriksson, A. (1990). Twinning in families of triplets. Acta Geneticae et Gemellologiae, 39, 279-293.
6. Goodship, J., Carter, J., & Burn, J. (1996). X-inactivation patterns in monozygotic and dizygotic female twins. American Journal of Medical Genetics, 61, 205-208.
7. Jones, H. (2003). Multiple births: how are we doing? Fertility and Sterility, 79, 17-21.
8. Jorgensen, A., Philip, J., Christensen, B., Raskind, W., Matsushita, M., & Motulsky, A. (1992). Opposite patterns of X-inactivation in MZ twins discordant for red-green colour deficiency. American Journal of Human Genetics, 51, 291-298.
9. Langlois, S., Kwong, L., Wong, L., & Baldwin, V. (1994). Monochorionic placenta associated with dizygotic blood chimeric twins discordant for cystic fibrosis: Example of the limitation of zygosity determination based on placental and blood studies. American Journal of Human Genetics, 55 Suppl, A125 (abstract).
10. Leonard, N., Johnson, C., Rudd, N., Machin, G., Bamforth, F., Bamforth, S., & Grundy, P. (1996). Two pairs of male monozygotic twins discordant for Beckwith-Wiedeman syndrome. American Journal of Medical Genetics, 61, 253-257.
11. Lichenstein, P., Otterblad Olausson, P., & Kallen A. (1996). Twin births to mothers who are twins: A registry based twins. British Medical Journal, 312, 879-881.
12. Lupski, J., Garcia, G., Zoghbi, H., Hoffman, E., & Fenwick, D. (1991). Discordance of muscular dystrophy in monozygotic female twins: Evidence supporting asymmetric splitting of the inner cell mass in a manifesting carrier of Duchenne dystrophy. American Journal of Medical Genetics, 40, 354-364.
13. Machin, G. (1996). Some causes of genotype and phenotypic discordance in monozygotic twin pairs. American Journal of Medical Genetics, 61, 216-228.
14. Machin, G. (1999a). Biology of twins and other multiple pregnancies. In G. Machin & K. Louis (Eds.), An atlas of multiple pregnancy (pp. 13-24). New York: Parthenon.
15. Machin, G. (1999b). Understanding the pathology of twin pregnancies. In G. Machin & K. Louis (Eds.), An atlas of multiple pregnancy (pp. 37-51). New York: Parthenon.
16. Machin, G., & Bamforth, F. (1996). Zygosity and placental anatomy in 15 consecutive cases of spontaneously conceived triplets. American Journal of Medical Genetics, 61, 247-252.
17. Machin, G., Bamforth, F., Innes, M., & McNichol, K. (1995). Some perinatal characteristics of monozygotic twins who are dichorionic. American Journal of Medical Genetics, 55, 71-76.
18. Martin, J., MacDorman, M., & Mathews, T. (1997). Triplet births: trends and outcomes, 1971-94. National Center for Health Statistics. National Vital Statistics Reports, 21, 1-20.
19. Schieve, L., Meikle, S., Peterson, H., Jeng, G., Burnett, N., & Wilcox, L. (2000). Does assisted hatching pose a risk for monozygotic twinning in pregnancies conceived through in vitro fertilization? Fertility and Sterility, 74, 288-294.
20. Sperber, G., Machin, G., & Bamforth, F. (1994). Mirror-image dental fusion and discordance in monozygotic twins. American Journal of Medical Genetics, 51, 41-45.
21. Souter, V., Kapur, R., Nyholt, D., Skogerboe, K., Myerson, D., Ton, C., Opheim, K., Easterling, T., Shields, L., Montgomery, G., & Glass, I. (2003). A report of dizygous monochorionic twins. New England Journal of Medicine, 349,154-158.
22. Ventura, S., Martin, J., Curtin, S., Menacker, F., & Hamilton, B. (2001). Births: Final data for 1999. National Vital Statistics Reports, 49, 1-99.
23. Westergard, T., Wohlfahrt, J., Aaby, P., & Melbye, M. (1997). Population based study of rates of multiple pregnancies in Denmark, 1980-94. British Medical Journal, 314, 775-779.