Factor II gene (prothrombin G20210A) mutation and neonatal cerebrovenous thrombosis

Thrombosis and Haemostasis

Volumn 92, Issue 4, 2004, Pages 719-721

  Swarte, Renate ^a,b   Appel, Inge ^a,b   Lequin, Maarten ^a,b   van Mol, Christine ^a,b   Govaert, Paul ^a,b  

^a SINT AUGUSTINUS HOSPITAL   (Belgium)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; BLOOD CLOTTING FACTOR 5 LEIDEN; DNA; GUANINE; PROTHROMBIN;

APGAR SCORE; ARTICLE; BIRTH WEIGHT; BRAIN HEMORRHAGE; CASE REPORT; CESAREAN SECTION; CHILDBIRTH; COMPUTER ASSISTED TOMOGRAPHY; DEATH; DNA DETERMINATION; ECHOGRAPHY; ELECTROENCEPHALOGRAPHY; FAMILY HISTORY; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; HETEROZYGOSITY; HUMAN; MALE; NEWBORN; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; VACUUM EXTRACTION;

EID: 6344262242     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1614194     Document Type: Article

References (20)

1. deVeber G. Stroke and the child's brain: an overview of epidemiology, syndromes and risk factors. Curr Opin Neurol 2002; 15: 133-8.
2. Lynch JK, Hirtz DG, deVeber G, et al. Report of the national institute of neurological disorders and stroke workshop on perinatal and childhood stroke. Pediatrics 2002; 109: 116-23.
3. Connor SE, Jarosz JH. Magnetic resonance imaging of cerebral venous sinus thrombosis. Clin Radiol 2002; 57: 449-61.
4. Hanigan WC, Tracy PT, Tadros WS, et al. Neonatal cerebral venous thrombosis. Pediatr Neurosci 1988; 14: 177-83.
5. Aronis S, Bouza H, Pergantou H, et al. Prothrombotic factors in neonates with cerebral thrombosis and intraventricular hemorrhage. Acta Paediatr Suppl 2002; 438: 87-91.
6. Carvalho KS, Bodensteiner JB, Connolly PJ, et al. Cerebral venous thrombosis in children. J Child Neurol 2001; 16: 574-80.
7. Junker R, Koch HG, Auberger K, et al. Prothrombin G20210A gene mutation and further prothrombotic risk factors in childhood thrombophilia. Arterioscler Thromb Vasc Biol 1999; 19: 2568-72.
8. Poort SR, Rosendaal FR, Reitsma PM, et al. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
9. van Ommen CH, Heijboer H, van den Dool EJ, et al. Pediatric venous thromboembolic disease in one single center: congenital prothrombotic disorders and the clinical outcome. J Thromb Haemost 2003; 1: 2516-22.
10. Delsing BJP, Catsman-Berrevoets CE, Appel IM. Early prognostic indicators of outcome in ischemic childhood stroke. Pediatr Neurol 2001; 24: 283-9.
11. Schobess R, Junker R, Auberger K, et al. Factor V G1691A and prothrombin G20210A in childhood spontaneous venous thrombosis. Evidence of an age-dependent thrombotic onset in carriers of factor V G1691A and prothrombin G20210A mutation. Eur J Pediatr 1999; 158: S105-8.
12. von Ahsen N, Lewczuk P, Schütz E, et al. Prothrombin activity and concentrations in healthy subjects with and without the prothrombin G20210A mutation. Thromb Res 2000; 99: 549-56.
13. van Ommen CH, Heijboer H, Buller H, et al. Venous thromboembolism in childhood: A prospective two-year registry in The Netherlands. J Pediatr 2001; 139: 676-81.
14. Govaert P, Achten E, van Haesebrouck P, et al. Deep cerebral venous thrombosis in thalamoventricular hemorrhage of the term newborn. Pediatr Radiol 1992; 22: 123-7.
15. Voorhies TM, Lipper EG, Lee BC, et al. Occlusive vascular disease in asphyxiated newborn infants. J Pediatr 1984; 105: 92-6.
16. Edstrom CS, Christensen RD. Evaluation and treatment of thrombosis in the neonatal intensive care unit. Clin Perinatol 2000; 27: 623-41.
17. Friese S, Müller-Hansen I, Schöning M, et al. Isolated internal cerebral venous thrombosis in a neonate with increased lipoprotein (a) level: diagnostic and therapeutic considerations. Neuropediatrics 2003; 34: 36-9.
18. Nowak-Göttle U, Debus O, Findeisen M, et al. Lipoprotein (a): its role in childhood thromboembolism. Pediatrics 1997; 99: E11.
19. de Veber G, Chan AC, Monagle P, et al. Anticoagulation therapy in pediatric patients with sinovenous thrombosis. Arch Neurol 1988; 55: 1533-7.
20. Ehlers H, Courville CB. Thrombosis of internal cerebral veins in infancy and childhood. J Pediatr 1936; 8: 600-23.