Addressing the unmet medical need for safe and effective weight loss therapies

Obesity Research

Volumn 12, Issue 8, 2004, Pages 1191-1196

  Arbeeny, Cynthia M ^a  

^a Genzyme Drug Discovery and Development   (United States)

Author keywords

Antiobesity; Drug development; Metabolic syndrome; Pharmacotherapy; Weight loss

Indexed keywords

ANTIOBESITY AGENT;

ARTICLE; HUMAN; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; WEIGHT REDUCTION;

ANTI-OBESITY AGENTS; DIABETES MELLITUS, TYPE 2; HUMANS; METABOLIC SYNDROME X; OBESITY; WEIGHT LOSS;

EID: 6344260340     PISSN: 10717323     EISSN: None     Source Type: Journal    
DOI: 10.1038/oby.2004.150     Document Type: Review

References (11)

1. International Obesity Task Force. The Global Epidemic. http://www.iotf.org (Accessed June 2004).
2. Mokdad AH, Ford ES, Bowman BA, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA. 2003;289:76-9.
3. U.S. Department of Health and Human Services. Identification, Evaluation, and Treatment of Overweight and Obesity in Adults: Natioiwl Institutes of Health Publication Number 00-4084. Rockville, MD: U.S. Department of Health and Human Services; National Institutes of Health; National Heart, Lung, and Blood Institute; North American Association for the Study of Obesity; 2000.
4. U.S. Department of Health and Human Services. The Surgeon General's Call to Action to Prevent and Decrease Overweight and Obesity 2001. http://www.surgeongeneral.gov/topics/obesity (Accessed June 2004).
5. Willett WC, Manson JE, Stampfer MJ, et al. Weight, weight change and coronary heart disease in women. JAMA. 1995;273:461-5.
6. Ford ES, Williamson DF, Liu S. Weight change and diabetes incidence: findings from a national cohort of US adults. A J Epidemiol. 1997;146:214-22.
7. Mokdad AH, Ford ES, Bowman BA, et al. Diabetes trends in the U.S.: 1990-1998. Diabetes Care. 2000;23:1278-83.
8. Williamson DF, Thompson TJ, Thun M, Flanders D, Pamuk E, Byers T. Intentional weight loss and mortality among overweight individuals with diabetes. Diabetes Care. 2000;23:1499-504.
9. Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001;344:1343-50.
10. Goldstein DJ. Beneficial health effects of modest weight loss. Int J Obes. 1992;16:397-415.
11. Blackburn G. Effect of degree of weight loss on health benefits. Obes Res. 1995;3(Suppl 2):211-6s.