Management of hyperleukocytosis and prevention of tumor lysis syndrome with low-dose prednisone continuous infusion in children with acute lymphoblastic leukemia

Acta Haematologica

Volumn 121, Issue 1, 2009, Pages 56-62

  Ozdemir, Mehmet Akif ^a   Karakukcu, Musa ^a,b   Patiroglu, Turkan ^a   Torun, Yasemin Altuner ^a   Kose, Mehmet ^b  

^a Department of Pediatric Hematology/Oncology ^*  (Turkey)

^b ERCIYES UNIVERSITY MEDICAL FACULTY   (Turkey)

Author keywords

Acute lymphoblastic leukemia; Hyperleukocytosis; Leukapheresis; Leukostasis; Tumor lysis syndrome

Indexed keywords

ALLOPURINOL; BICARBONATE; PREDNISONE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ALKALINIZATION; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; DIALYSIS; DRUG DOSE INCREASE; DRUG TOLERABILITY; FEMALE; HUMAN; HYDRATION; HYPERLEUKOCYTOSIS; HYPERURICEMIA; HYPOCALCEMIA; LEUKOCYTE COUNT; LEUKOCYTOSIS; LOW DRUG DOSE; MALE; METABOLIC DISORDER; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; TUMOR LYSIS SYNDROME; UNSPECIFIED SIDE EFFECT;

ADOLESCENT; ANTINEOPLASTIC AGENTS, HORMONAL; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFUSIONS, INTRAVENOUS; LEUKOCYTOSIS; MALE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PREDNISONE; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; TUMOR LYSIS SYNDROME;

EID: 63349104608     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000210392     Document Type: Article

References (33)

1. Porcu P, Farag S, Marcucci G, Cataland SR, Kennedy MS, Bissell M: Leukocytoreduction for acute leukemia. Ther Apher 2002; 6: 15- 23.
2. Porcu P, Cripe LD, Ng EW, Bhatia S, Danielson CM, Orazi A, McCarthy LJ: Hyperleukocytic leukemias and leukostasis: a review of pathophysiology, clinical presentation and management. Leuk Lymphoma 2000; 39: 1- 18.
3. Maurer HS, Steinherz PG, Gaynon PS, Fink - lestein JZ, Sather HN, Reaman GH, Bleyer WA, Hammond GD: The effect of initial management of hyperleukocytosis on early complications and outcome of children with acute lymphoblastic leukemia. J Clin Oncol 1988; 6: 1425-1432.
4. Macfarlane RJ, McCully BJ, Fernandez CV: Rasburicase prevents tumor lysis syndrome despite extreme hyperleukocytosis. Pediatr Nephrol 2004; 19: 924-927.
5. Eguiguren JM, Schell MJ, Crist WM, Kunkel K, Rivera GK: Complications and outcome in childhood acute lymphoblastic leukemia with hyperleukocytosis. Blood 1992; 79: 871- 875.
6. Cairo MS, Bishop M: Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol 2004; 127: 3-11.
7. Kopecna L, Dolezel Z, Osvaldova Z, Starha J, Hrstkova H: The analysis of the risks for the development of tumour lysis syndrome in children. Bratisl Lek Listy 2002; 103: 206- 209.
8. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, Sultan C: Proposals for the classification of chronic (mature) B and T lymphoid leukaemias. French-American-British (FAB) Cooperative Group. J Clin Pathol 1989; 42: 567-584.
9. Lowe EJ, Pui CH, Hancock ML, Geiger TL, Khan RB, Sandlund JT: Early complications in children with acute lymphoblastic leukemia presenting with hyperleukocytosis. Pediatr Blood Cancer 2005; 44: 1-6.
10. Pui CH, Frankel LS, Carroll AJ, Raimondi SC, Shuster JJ, Head DR, Crist WM, Land VJ, Pullen DJ, Steuber CP, Behm FG, Borowitz MJ: Clinical characteristics and treatment outcome of childhood acute lymphoblastic leukemia with the t(4; 11)(q21;q23): a collaborative study of 40 cases. Blood 1991; 77: 440- 447.
11. Crist W, Carroll A, Shuster J, Jackson J, Head D, Borowitz M, Behm F, Link M, Steuber P, Ragab A, Hirt A, Brock B, Land V, Pullen J: Philadelphia chromosome positive childhood acute lymphoblastic leukemia: clinical and cytogenetic characteristics and treatment outcome. A Pediatric Oncology Group study. Blood 1990; 76: 489-494.
12. Lester TJ, Johnson JW, Cuttner J: Pulmonary leukostasis as the single worst prognostic factor in patients with acute myelocytic leukemia and hyperleukocytosis. Am J Med 1985; 79: 43-48.
13. Grima KM: Therapeutic apheresis in hematological and oncological diseases. J Clin Apheresis 2000; 15: 28-52.
14. Sloan SR, Benjamin RJ, Friedman DF, Webb IJ, Silberstein L: Transfusion medicine; in Nathan DG, Orkin SH, Ginsburg D, Look AT (eds): Hematology of Infancy and Childhood. Philadelphia, WB Saunders, 2003, vol 2, pp 1744-1745.
15. Porcu P, Danielson CF, Orazi A, Heerema NA, Gabig TG, McCarthy LJ: Therapeutic leukapheresis in hyperleucocytic leukaemias: lack of correlation between degree of cytoreduction and early mortality rate. Br J Haematol 1997; 98: 433-436.
16. Giles FJ, Shen Y, Kantarjian HM, Korbling MJ, O'Brien S, Anderlini P, Donato M, Pierce S, Keating MJ, Freireich EJ, Estey E: Leukapheresis reduces early mortality in patients with acute myeloid leukemia with high white cell counts but does not improve long-term survival. Leuk Lymphoma 2001; 42: 67-73.
17. Majhail NS, Lichtin AE: Acute leukemia with a very high leukocyte count: confronting a medical emergency. Cleve Clin J Med 2004; 71: 633-637.
18. Basade M, Dhar AK, Kulkarni SS, Sastry PS, Yadav RP, Parikh BS, Pai SK, Nair CN, Kurkure PA, Advani SH: Rapid cytoreduction in childhood leukemic hyperleukocytosis by conservative therapy. Med Pediatr Oncol 1995; 25: 204-207.
19. Bunin NJ, Pui CH: Differing complications of hyperleukocytosis in children with acute lymphoblastic or acute nonlymphoblastic leukemia. J Clin Oncol 1985; 3: 1590-1595.
20. Kaczmarek-Kanold M, Radwanska U, Boguslawska- Jaworska J, Rodziewicz B: Exchange transfusion in children with blastic hyperleukocytosis in acute lymphoblastic leukemia. Acta Haematol Pol 1991; 22: 290-296.
21. Bunin NJ, Kunkel K, Callihan TR: Cytoreductive procedures in the early management in cases of leukemia and hyperleukocytosis in children. Med Pediatr Oncol 1987; 15: 232- 235.
22. Woloskie S, Armelagos H, Meade JM, Haas D: Leukodepletion for acute lymphocytic leukemia in a three-week-old infant. J Clin Apheresis 2001; 16: 31-32.
23. Legrand O, Marie JP, Cadiou M, Blanc C, Ramon S, Zittoun R: Early cytoreduction: a major prognostic factor in adult acute lymphoblastic leukemia. Leuk Lymphoma 1994; 15: 433-438.
24. Strauss RA, Gloster ES, McCallister JA, Jimenez JF, Neuberg RW, Berry DH: Acute cytoreduction techniques in the early treatment of hyperleukocytosis associated with childhood hematologic malignancies. Med Pediatr Oncol 1985; 13: 346-351.
25. Nelson SC, Bruggers CS, Kurtzberg J, Friedman HS: Management of leukemic hyperleukocytosis with hydration, urinary alkalinization, and allopurinol. Are cranial irradia - tion and invasive cytoreduction necessary? Am J Pediatr Hematol Oncol 1993; 15: 351- 355.
26. Irken G, Oren H, Oniz H, Cetingul N, Vergin C, Atabay B, Gulen H, Turker M, Kantar M, YIlmaz S: Hyperleukocytosis in childhood acute lymphoblastic leukemia: complications and treatment outcome. Turk J Hematol 2006; 23: 142-146.
27. Goldman SC, Holcenberg JS, Finklestein JZ, Hutchinson R, Kreissman S, Johnson FL, Tou C, Harvey E, Morris E, Cairo MS: A randomized comparison between rasburicase and allopurinol in children with lymphoma or leukemia at high risk for tumor lysis. Blood 2001; 97: 2998-3003.
28. Lee AC, Li CH, So KT, Chan R: Treatment of impending tumor lysis with single-dose rasburicase. Ann Pharmacother 2003; 37: 1614- 1617.
29. Patte C, Sakiroglu O, Sommelet D: European experience in the treatment of hyperuricemia. Semin Hematol 2001; 38: 9-12.
30. Pui CH: Urate oxidase in the prophylaxis or treatment of hyperuricemia: the United States experience. Semin Hematol 2001; 38: 13-21.
31. Bubala H, Sonta-Jakimczyk D, Szczepanska M, Szprynger K: Tumor lysis syndrome in the course of acute lymphoblastic leukemia as the consequence of prednisone monotherapy (in Polish). Pol Merkur Lekarski 2003; 15: 182-184.
32. He H, Li C, Han M: Acute lymphoblastic leukemia complicated with tumor lysis syndrome: four cases report (in Chinese). Zhonghua Xue Ye Xue Za Zhi 1999; 20: 310-312.
33. Duzova A, Cetin M, Gumruk F, Yetgin S: Acute tumour lysis syndrome following a single-dose corticosteroid in children with acute lymphoblastic leukaemia. Eur J Haematol 2001; 66: 404-407.