Elderly patients with advanced colorectal cancer derive similar benefit without excessive toxicity after first-line chemotherapy with oxaliplatin-based combinations: Comparative outcomes from the 03-TTD-01 phase III study

Critical Reviews in Oncology/Hematology

Volumn 70, Issue 2, 2009, Pages 134-144

  Sastre, Javier ^a   Aranda, Enrique ^b   Massutí, Bartomeu ^c   Tabernero, Jose ^d   Chaves, Manuel ^e   Abad, Albert ^f   Carrato, Alfredo ^c   Reina, Juan José ^c   Queralt, Bernardo ^c   Gómez España, Auxiliadora ^b   González Flores, Encarnación ^g   Rivera, Fernando ^c   Losa, Ferrán ^h   García, Teresa ^c   Sanchez Rovira, Pedro ^c   Maestu, Inmaculada ⁱ   Díaz Rubio, Eduardo ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^b HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^c H General Alicante ^*  (Spain)

^d HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^e HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^f HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^g HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^h Hospitalet   (Spain)

ⁱ HOSPITAL VIRGEN DE LOS LIRIOS   (Spain)

Author keywords

5 FU; Capecitabine; Elderly patients; Metastatic colorectal cancer; Oxaliplatin

Indexed keywords

CAPECITABINE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN;

ABDOMINAL PAIN; ADULT; ADVANCED CANCER; AGE DISTRIBUTION; AGED; AGING; AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; ANOREXIA; ASTHENIA; CLINICAL TRIAL; COLORECTAL CANCER; COMBINATION CHEMOTHERAPY; COMPARATIVE STUDY; CONSTIPATION; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIARRHEA; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; FEMALE; FEVER; GERIATRIC PATIENT; HAND FOOT SYNDROME; HUMAN; HYPERBILIRUBINEMIA; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; METASTASIS; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; OVERALL SURVIVAL; PARESTHESIA; PHASE 3 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; RASH; REVIEW; SIDE EFFECT; STATISTICAL ANALYSIS; THROMBOCYTOPENIA; TREATMENT OUTCOME; TREATMENT RESPONSE; VOMITING;

AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COLORECTAL NEOPLASMS; DEOXYCYTIDINE; FEMALE; FLUOROURACIL; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; ORGANOPLATINUM COMPOUNDS;

EID: 63249122590     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2008.11.002     Document Type: Review

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