Preparation of enantiopure (R)-hydroxy metabolite of denbufylline using immobilized Lactobacillus kefiri DSM 20587 as a catalyst

Chirality

Volumn 21, Issue 8, 2009, Pages 713-718

  Pekala, Elizbieta ^a   Burbiel, Joachim C ^b   Müller, Christa E ^b  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Alcohol dehydrogenase; Biotransformation; Denbufylline; Enantioselectivity; Hydroxy metabolite; Immobilized cells; Lactobacillus kefiri

Indexed keywords

1,3 DIBUTYL 7 [2 HYDROXYPROPYL] 1H PURINE 2,6 (3H,7H)DIONE; ACETONE; ACETONITRILE; BRL 31532; DENBUFYLLINE; DIMETHYL SULFOXIDE; DRUG METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; BIOCATALYST; BIOTRANSFORMATION; CHEMICAL REACTION; CONTROLLED STUDY; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; IMMOBILIZED CELL; LACTOBACILLUS; LACTOBACILLUS KERIFI; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REDUCTION;

BIOCATALYSIS; CELLS, IMMOBILIZED; ENZYMES, IMMOBILIZED; HYDROXY ACIDS; KETONES; LACTOBACILLUS; PURINES; STEREOISOMERISM; XANTHINES;

EID: 63149121444     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20665     Document Type: Article

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