Probable deceleration of progression of simian AIDS affected by opiate dependency: Studies with a rhesus macaque/sivsmm9 model

Journal of Acquired Immune Deficiency Syndromes

Volumn 50, Issue 3, 2009, Pages 241-249

  Donahoe, Robert M ^a,b,c   O'Neil, Shawn P ^b,c,d   Marsteller, Frederick A ^e   Novembre, Francis J ^b,c   Anderson, Daniel C ^c   Lankford Turner, Pamela ^b   McClure, Harold H ^b,c  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e Behavioral Research Consulting   (United States)

Author keywords

AIDS; Opiates; Pathology; SIV; Survival

Indexed keywords

MORPHINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BRANCHED DNA SIGNAL AMPLIFICATION ASSAY; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOFLUOROMETRY; DISEASE COURSE; IMMUNE STATUS; MONKEY DISEASE; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; PROGNOSIS; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS LOAD; VIRUS TITRATION; ANIMAL; ISOLATION AND PURIFICATION; LONGITUDINAL STUDY; MACACA; MALE; MASS FRAGMENTOGRAPHY; PATHOLOGY;

ANIMALS; DISEASE PROGRESSION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LONGITUDINAL STUDIES; MACACA MULATTA; MALE; OPIOID-RELATED DISORDERS; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL LOAD;

EID: 63149106094     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e3181967354     Document Type: Article

References (82)

1. Risdahl JM, Khanna KV, Peterson PK, et al. Opiates and infection. J Neuroimmunol. 1998;83:4-18.
2. Pert CB, Snyder SH. Opiate receptor: demonstration in nervous tissue. Science. 1973;179:1011-1014.
3. 3H-etorphine to rat brain homogenates. Proc Natl Acad Sci U S A. 1973;70:1947-1949.
4. Lopker A, Abood LG, Hoss W, et al. Stereospecific muscarinic acetycholine and opiate receptors in human phagocytic leukocytes. Biochem Pharmacol. 1980;29:1361-1365.
5. Gottlieb MS, Schroff R, Schanker HM, et al. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. N Engl J Med. 1981;305:1425-1431.
6. Wormser GP, Krupp LB, Hanrahan JP, et al. Acquired immunodeficiency syndrome in male prisoners. New insights into an emerging syndrome. Ann Intern Med. 1983;98:297-303.
7. National Institute on Drug Abuse Research Report Series. Rockville, MD: NIH; 2006. Publication No. 06-5760.
8. Raine CS, Sharp CW, eds. Special issue: pharmaconeuroimmunology, AIDS and other diseases. J Neuroimmunol. 1998;83:1-173.
9. Peterson PK, Sharp B, Gekker G, et al. Morphine promotes the growth of HIV-1 in human peripheral blood mononuclear cell cultures. AIDS. 1990; 4:869-873.
10. Donahoe RM, Nicholson JKA, Madden JJ, et al. Coordinate and independent effects of heroin, cocaine and alcohol abuse on T-cell E-rosette formation and antigenic marker expression. Clin Immunol Immunopath. 1986;41:254-264.
11. Donahoe RM, Bryd LD, McClure HH, et al. Coordinate effects of stress and opiates in modulating immunity in rhesus monkeys. NIDA Res Monograph. 1993; 132:70.
12. Bayer BM, Brehio RM, Ding XZ, et al. Enhanced susceptibility of the immune system to stress in morphine tolerant rats. Brain Behav Immun. 1994;8:173-184.
13. Donahoe RM. Neuroimmunomodulation by opiates: relationship to HIV-1 infection and AIDS. Adv Neuroimmunol. 1993;3:31-46.
14. Donahoe RM, Vlahov D. Opiates as potential cofactors in progression of HIV-1 infections to AIDS. J Neuroimmunol. 1998;83:77-87.
15. Kapadia F, Vlahov D, Donahoe RM, et al. The role of substance abuse in HIV disease progression: reconciling differences from laboratory and epidemiologic investigations. Clin Infect Dis. 2005;41:1027-1034.
16. Donahoe RM, Bryd LD, McClure HH, et al. Consequences of opiate dependency in a monkey model of AIDS. Adv Exp Med Biol. 1993;335: 21-28.
17. Chuang RY, Blackbourne DJ, Chuang LF, et al. Modulation of simian AIDS by opioids. Adv Biosci. 1993;86:573-583.
18. Kumar R, Torres C, Yamamura Y, et al. Modulation by morphine of viral set point in rhesus macaques infected with simian immunodeficiency virus and simian-human immunodeficiency virus. J Virol. 2004;78: 11425-11428.
19. Fultz PN, McClure HM, Anderson DC, et al. Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cerocebus atys). Proc Natl Acad Sci U S A. 1986;83:5286-5290.
20. Dewar RL, Highbarger HC, Sarmiento MD, et al. Application of branched DNA signal amplification to monitor human immunodeficiency virus type 1 burden in human plasma. J Infect Dis. 1994; 170:1172-1179.
21. Woods JH, Winger GD, Medzihradsky F, et al. Evaluation of new compounds for opioid activity in rhesus monkey, rat and mouse. NIDA Res Monogr. 1984;55:309-393.
22. Wang Y-C, Lankford-Turner P, Madden JJ, et al. A modified ELISA assay for testing monkey anti-morphine antibody. Presented at: 8th Conference of the Society on Neuroimmune Pharmacology; March 23, 2001; Atlanta, GA.
23. Donahoe RM, Byrd LD, McClure HM, et al. Effects of morphine on T-cell recircultation in rhesus monkeys. Adv Exp Med Biol. 2001:89-101.
24. Rubin DB. Inference and missing data. Biometrika. 1976;63:581-592.
25. Leserman J, Petitto JM, Gu H, et al. Progression to AIDS, a clinical AIDS condition and mortality: psychosocial and physiological predictors. Psychol Med. 2002;32:1059-1073.
26. Capitanio JP, Mendoza SP, Lerche NW, et al. Social stress results in altered glucocorticoid regulation and shorter survival in simian acquired immune deficiency syndrome. Proc Natl Acad Sci U S A. 1998;95:4714-4719.
27. Risdahl JM, Peterson PK, Chao CC, et al. Effects of morphine dependence on the pathogenesis of swine herpes virus infection. J Infect Dis. 1993: 1281-1287.
28. Veryies, M-L, Sinet M, Desforges B, et al. Effects of morphine on the pathogenesis of murine Friend retrovirus infection. J Pharmacol Exp Ther. 1995;272:498-504.
29. Alonzo NC, Carr DJ. Morphine reduces mortality in mice following ocular infection with HSV-1. Immunopharmacology. 1999;41:187-197.
30. Barr MC, Billaud JN, Selway DR, et al. Effects of multiple acute morphine exposures on feline immunodeficiency virus disease progression. J Infect Dis. 2000:182:725-732.
31. Feinberg MB, McCune JM, Miedema F, et al. HIV tropism and CD4+ T-cell depletion. Nat Med. 2002;8:537.
32. Fuchs BA, Pruett SB. Morphine induces apoptosis in murine thymocytes in vivo but not in vitro: involvement of both opiate and glucocorticoid receptors. J Pharmacol Exp Ther. 1993;266:417-423.
33. Singhal PC, Sharma P, Kapasi AA, et al. Morphine enhances macrophage apoptosis. J Immunol. 1998;160:1886-1893.
34. Lu W, Andrieu JM. Apoptosis and HIV disease. Nat Med. 1995;1: 386-387.
35. Gougeon ML, Laurent-Crawford AG, Hovanessian AG, et al. Direct and indirect mechanisms mediating apoptosis during HIV infection: contribution to in vivo CD4 T cell depletion. Semin Immunol. 1993;5:187-194.
36. Levy R, Jais JP, Tourani JM, et al. Long-term follow-up of HIV positive asymptomatic patients having received cyclosporine. Adv Exp Med Biol. 1995;374:229-234
37. Andrieu JM, Lu W, Levy R. Sustained increases in CD4 cell counts in asymptomatic human immunodeficiency virus type 1-seropositive patients treated with prednisolone for 1 year. J Infect Dis. 1995; 171: 523-530.
38. Spijkerman IJ, Koot M, Prins M, et al. Lower prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users compared with homosexual men. AIDS. 1995;9:1085-1092.
39. Spijkerman IJ, Langendam MW, Veugelers PJ, et al. Differences in progression to AIDS between injection drug users and homosexual men with documented dates of seroconversion. Epidemiology. 1996;7: 571-577.
40. Tubaro E, Borelli G, Croce C, et al. Effect of morphine on resistance to infection. J Infect Dis. 1983;148:656-666.
41. Coussons-Read ME, Daniels M, Gilmour MI. Morphine alters the immune response to influenza virus infection in Lewis rats. Adv Exp Med Biol. 1988;437:73-82.
42. Risdahl JM, Khanna KV, Peterson PK, et al. Opiates and infection. J Neuroimmunol. 1998;83:4-18.
43. Pert CB, Snyder SH. Opiate receptor: demonstration in nervous tissue. Science. 1973;179:1011-1014.
44. 3H-etorphine to rat brain homogenates. Proc Natl Acad Sci U S A. 1973;70:1947-1949.
45. Lopker A, Abood LG, Hoss W, et al. Stereospecific muscarinic acetycholine and opiate receptors in human phagocytic leukocytes. Biochem Pharmacol. 1980;29:1361-1365.
46. Gottlieb MS, Schroff R, Schanker HM, et al. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. N Engl J Med. 1981;305:1425-1431.
47. Wormser GP, Krupp LB, Hanrahan JP, et al. Acquired immunodeficiency syndrome in male prisoners. New insights into an emerging syndrome. Ann Intern Med. 1983;98:297-303.
48. National Institute on Drug Abuse Research Report Series. Rockville, MD: NIH; 2006. Publication No. 06-5760.
49. Raine CS, Sharp CW, eds. Special issue: pharmaconeuroimmunology, AIDS and other diseases. J Neuroimmunol. 1998;83:1-173.
50. Peterson PK, Sharp B, Gekker G, et al. Morphine promotes the growth of HIV-1 in human peripheral blood mononuclear cell cultures. AIDS. 1990; 4:869-873.
51. Donahoe RM, Nicholson JKA, Madden JJ, et al. Coordinate and independent effects of heroin, cocaine and alcohol abuse on T-cell E-rosette formation and antigenic marker expression. Clin Immunol Immunopath. 1986;41:254-264.
52. Donahoe RM, Bryd LD, McClure HH, et al. Coordinate effects of stress and opiates in modulating immunity in rhesus monkeys. NIDA Res Monograph. 1993; 132:70.
53. Bayer BM, Brehio RM, Ding XZ, et al. Enhanced susceptibility of the immune system to stress in morphine tolerant rats. Brain Behav Immun. 1994;8:173-184.
54. Donahoe RM. Neuroimmunomodulation by opiates: relationship to HIV-1 infection and AIDS. Adv Neuroimmunol. 1993;3:31-46.
55. Donahoe RM, Vlahov D. Opiates as potential cofactors in progression of HIV-1 infections to AIDS. J Neuroimmunol. 1998;83:77-87.
56. Kapadia F, Vlahov D, Donahoe RM, et al. The role of substance abuse in HIV disease progression: reconciling differences from laboratory and epidemiologic investigations. Clin Infect Dis. 2005;41:1027-1034.
57. Donahoe RM, Bryd LD, McClure HH, et al. Consequences of opiate dependency in a monkey model of AIDS. Adv Exp Med Biol. 1993;335: 21-28.
58. Chuang RY, Blackbourne DJ, Chuang LF, et al. Modulation of simian AIDS by opioids. Adv Biosci. 1993;86:573-583.
59. Kumar R, Torres C, Yamamura Y, et al. Modulation by morphine of viral set point in rhesus macaques infected with simian immunodeficiency virus and simian-human immunodeficiency virus. J Virol. 2004;78: 11425-11428.
60. Fultz PN, McClure HM, Anderson DC, et al. Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cerocebus atys). Proc Natl Acad Sci U S A. 1986;83:5286-5290.
61. Dewar RL, Highbarger HC, Sarmiento MD, et al. Application of branched DNA signal amplification to monitor human immunodeficiency virus type 1 burden in human plasma. J Infect Dis. 1994; 170:1172-1179.
62. Woods JH, Winger GD, Medzihradsky F, et al. Evaluation of new compounds for opioid activity in rhesus monkey, rat and mouse. NIDA Res Monogr. 1984;55:309-393.
63. Wang Y-C, Lankford-Turner P, Madden JJ, et al. A modified ELISA assay for testing monkey anti-morphine antibody. Presented at: 8th Conference of the Society on Neuroimmune Pharmacology; March 23, 2001; Atlanta, GA.
64. Donahoe RM, Byrd LD, McClure HM, et al. Effects of morphine on T-cell recircultation in rhesus monkeys. Adv Exp Med Biol. 2001:89-101.
65. Rubin DB. Inference and missing data. Biometrika. 1976;63:581-592.
66. Leserman J, Petitto JM, Gu H, et al. Progression to AIDS, a clinical AIDS condition and mortality: psychosocial and physiological predictors. Psychol Med. 2002;32:1059-1073.
67. Capitanio JP, Mendoza SP, Lerche NW, et al. Social stress results in altered glucocorticoid regulation and shorter survival in simian acquired immune deficiency syndrome. Proc Natl Acad Sci U S A. 1998;95:4714-4719.
68. Risdahl JM, Peterson PK, Chao CC, et al. Effects of morphine dependence on the pathogenesis of swine herpes virus infection. J Infect Dis. 1993: 1281-1287.
69. Veryies, M-L, Sinet M, Desforges B, et al. Effects of morphine on the pathogenesis of murine Friend retrovirus infection. J Pharmacol Exp Ther. 1995;272:498-504.
70. Alonzo NC, Carr DJ. Morphine reduces mortality in mice following ocular infection with HSV-1. Immunopharmacology. 1999;41:187-197.
71. Barr MC, Billaud JN, Selway DR, et al. Effects of multiple acute morphine exposures on feline immunodeficiency virus disease progression. J Infect Dis. 2000:182:725-732.
72. Feinberg MB, McCune JM, Miedema F, et al. HIV tropism and CD4+ T-cell depletion. Nat Med. 2002;8:537.
73. Fuchs BA, Pruett SB. Morphine induces apoptosis in murine thymocytes in vivo but not in vitro: involvement of both opiate and glucocorticoid receptors. J Pharmacol Exp Ther. 1993;266:417-423.
74. Singhal PC, Sharma P, Kapasi AA, et al. Morphine enhances macrophage apoptosis. J Immunol. 1998;160:1886-1893.
75. Lu W, Andrieu JM. Apoptosis and HIV disease. Nat Med. 1995;1: 386-387.
76. Gougeon ML, Laurent-Crawford AG, Hovanessian AG, et al. Direct and indirect mechanisms mediating apoptosis during HIV infection: contribution to in vivo CD4 T cell depletion. Semin Immunol. 1993;5:187-194.
77. Levy R, Jais JP, Tourani JM, et al. Long-term follow-up of HIV positive asymptomatic patients having received cyclosporine. Adv Exp Med Biol. 1995;374:229-234
78. Andrieu JM, Lu W, Levy R. Sustained increases in CD4 cell counts in asymptomatic human immunodeficiency virus type 1-seropositive patients treated with prednisolone for 1 year. J Infect Dis. 1995; 171: 523-530.
79. Spijkerman IJ, Koot M, Prins M, et al. Lower prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users compared with homosexual men. AIDS. 1995;9:1085-1092.
80. Spijkerman IJ, Langendam MW, Veugelers PJ, et al. Differences in progression to AIDS between injection drug users and homosexual men with documented dates of seroconversion. Epidemiology. 1996;7: 571-577.
81. Tubaro E, Borelli G, Croce C, et al. Effect of morphine on resistance to infection. J Infect Dis. 1983;148:656-666.
82. Coussons-Read ME, Daniels M, Gilmour MI. Morphine alters the immune response to influenza virus infection in Lewis rats. Adv Exp Med Biol. 1988;437:73-82.