Preparation and biological evaluation of a glycosylated fusion interferon directed to hepatic receptors

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 3, 2009, Pages 440-443

  Cai, Gangming ^a,b   Jiang, Mengjun ^b   Zhang, Bo ^b   Zhou, Yaoyuan ^b   Zhang, Lianfen ^a   Lei, Jianyong ^a   Gu, Xiaobo ^b   Cao, Guoxian ^b   Jin, Jian ^a   Zhang, Rongjun ^a,b  

^a JIANGNAN UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

Asialoglycoprotein receptor; Galactosylated fusion interferon; Targeted drug

Indexed keywords

2 IMINO 2 ETHYLOXYMETHYL 1 THIOGALACTOSE; ALPHA2B INTERFERON; ASIALOGLYCOPROTEIN RECEPTOR; GALACTOSE; GALACTOSYL HUMAN SERUM ALBINTERFERON ALPHA2B; GALACTOSYL HUMAN SERUM ALBINTERFERON ALPHA2B I 125; HUMAN SERUM ALBINTERFERON ALPHA2B; HUMAN SERUM ALBINTERFERON ALPHA2B I 125; HYBRID PROTEIN; INTERFERON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; FEMALE; GLYCOSYLATION; ISOTOPE LABELING; LIVER CELL; MALE; MOUSE; NONHUMAN;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; FEMALE; GLYCOSYLATION; HEPATOCYTES; HUMANS; INTERFERON ALFA-2B; MALE; MICE; MICE, INBRED ICR; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SERUM ALBUMIN; TISSUE DISTRIBUTION; VESICULOVIRUS;

EID: 63149091637     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.440     Document Type: Article

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