The conserved WW-domain binding sites in Dystroglycan C-terminus are essential but partially redundant for Dystroglycan function

BMC Developmental Biology

Volumn 9, Issue 1, 2009, Pages

  Yatsenko, As ^a,b,c   Kucherenko, Mm ^a,b,c   Pantoja, M ^a   Fischer, Ka ^a   Madeoy, J ^d   Deng, W M ^e   Schneider, M ^f   Baumgartner, S ^g   Akey, J ^d   Shcherbata, Hr ^a,c   Ruohola Baker, H ^a,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b IVAN FRANKO NATIONAL UNIVERSITY OF LVIV   (Ukraine)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^d UNIVERSITY OF WASHINGTON   (United States)

^e FLORIDA STATE UNIVERSITY   (United States)

^f UNIVERSITY OF COPENHAGEN   (Denmark)

^g LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DYSTROGLYCAN; DROSOPHILA PROTEIN; DYSTROPHIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GENE MUTATION; GENE SEQUENCE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; AMINO ACID SEQUENCE; ANIMAL; CELL POLARITY; CHEMISTRY; CYTOLOGY; CYTOSKELETON; DROSOPHILA; DROSOPHILA MELANOGASTER; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; OOCYTE; PHYLOGENY; TRANSGENIC ANIMAL;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BINDING SITES; CELL POLARITY; CONSERVED SEQUENCE; CYTOSKELETON; DROSOPHILA; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; DYSTROGLYCANS; DYSTROPHIN; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; OOCYTES; PHYLOGENY;

EID: 63149088196     PISSN: None     EISSN: 1471213X     Source Type: Journal    
DOI: 10.1186/1471-213X-9-18     Document Type: Article

References (32)

1. Characterization of the beta-dystroglycan-growth factor receptor 2 (Grb2) interaction. K Russo E Di Stasio G Macchia G Rosa A Brancaccio TC Petrucci, Biochem Biophys Res Commun 2000 274 93 8 10.1006/bbrc.2000.3103 10903901
2. Binding of laminin alpha1-chain LG4-5 domain to alpha-dystroglycan causes tyrosine phosphorylation of syntrophin to initiate Rac1 signaling. YW Zhou DB Thomason D Gullberg HW Jarrett, Biochemistry 2006 45 2042 52 10.1021/bi0519957 16475793
3. Molecular mechanisms of muscular dystrophies: old and new players. KE Davies KJ Nowak, Nat Rev Mol Cell Biol 2006 7 762 73 10.1038/nrm2024 16971897
4. Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue. T Haenggi JM Fritschy, Cell Mol Life Sci 2006 63 1614 31 10.1007/s00018-005-5461-0 16710609
5. Dystroglycan: from biosynthesis to pathogenesis of human disease. R Barresi KP Campbell, J Cell Sci 2006 119 199 207 10.1242/jcs.02814 16410545
6. Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy. HR Shcherbata AS Yatsenko L Patterson VD Sood U Nudel D Yaffe D Baker H Ruohola-Baker, Embo J 2007 26 481 93 17215867 10.1038/sj.emboj.7601503
7. Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila. WM Deng M Schneider R Frock C Castillejo-Lopez EA Gaman S Baumgartner H Ruohola-Baker, Development 2003 130 173 84 10.1242/dev.00199 12441301
8. Cell-cell communication and axis specification in the Drosophila oocyte. JS Poulton WM Deng, Dev Biol 2007 311 1 10 17884037 10.1016/j.ydbio.2007.08.030
9. Dystroglycan and perlecan provide a basal cue required for epithelial polarity during energetic stress. V Mirouse CP Christoforou C Fritsch D St Johnston RP Ray, Dev Cell 2009 16 83 92 10.1016/j.devcel.2008.11.006 19154720
10. Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants. MJ Allikian G Bhabha P Dospoy A Heydemann P Ryder JU Earley MJ Wolf HA Rockman EM McNally, Hum Mol Genet 2007 16 2933 43 10.1093/hmg/ddm254 17855453
11. Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype. O Taghli-Lamallem T Akasaka G Hogg U Nudel D Yaffe JS Chamberlain K Ocorr R Bodmer, Aging Cell 2008 7 237 49 10.1111/j.1474-9726. 2008.00367.x 18221418
12. Temporal and spatial transcriptional profiles of aging in Drosophila melanogaster. M Zhan H Yamaza Y Sun J Sinclair H Li S Zou, Genome Res 2007 17 1236 43 17623811 10.1101/gr.6216607
13. A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila. AS Yatsenko EE Gray HR Shcherbata LB Patterson VD Sood MM Kucherenko D Baker H Ruohola-Baker, J Biol Chem 2007 282 15159 69 10.1074/jbc.M608800200 17355978
14. Identification and characterization of the dystrophin anchoring site on beta-dystroglycan. D Jung B Yang J Meyer JS Chamberlain KP Campbell, J Biol Chem 1995 270 27305 10 10.1074/jbc.270.45.27305 7592992
15. The WW domain of dystrophin requires EF-hands region to interact with beta-dystroglycan. S Rentschler H Linn K Deininger MT Bedford X Espanel M Sudol, Biol Chem 1999 380 431 42 10.1515/BC.1999.057 10355629
16. Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan. X Huang F Poy R Zhang A Joachimiak M Sudol MJ Eck, Nat Struct Biol 2000 7 634 8 10.1038/77923 10932245
17. Function of the Drosophila CPEB protein Orb2 in long-term courtship memory. K Keleman S Kruttner M Alenius BJ Dickson, Nat Neurosci 2007 10 1587 93 10.1038/nn1996 17965711
18. Dystroglycan overexpression in vivo alters acetylcholine receptor aggregation at the neuromuscular junction. RD Heathcote JM Ekman KP Campbell EW Godfrey, Dev Biol 2000 227 595 605 10.1006/dbio.2000.9906 11071777
19. A role for the juxtamembrane domain of beta-dystroglycan in agrin-induced acetylcholine receptor clustering. J Kahl JT Campanelli, J Neurosci 2003 23 392 402 12533599
20. Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex. MM Kucherenko M Pantoja AS Yatsenko HR Shcherbata KA Fischer DV Maksymiv YI Chernyk H Ruohola-Baker, PLoS ONE 2008 3 e2418 18545683 10.1371/journal.pone.0002418
21. Quantitative analysis of gene function in the Drosophila embryo. WD Tracey Jr X Ning M Klingler SG Kramer JP Gergen, Genetics 2000 154 273 84 10628987
22. Regulation of zygotic gene expression in Drosophila primordial germ cells. M Van Doren AL Williamson R Lehmann, Curr Biol 1998 8 243 6 10.1016/S0960-9822(98)70091-0 9501989
23. DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. U Hacker N Perrimon, Genes Dev 1998 12 274 84 9436986 10.1101/gad.12.2.274
24. Induction of Drosophila eye development by decapentaplegic. F Pignoni SL Zipursky, Development 1997 124 271 8 9053304
25. The detached locus encodes Drosophila Dystrophin, which acts with other components of the Dystrophin Associated Protein Complex to influence intercellular signalling in developing wing veins. CP Christoforou CE Greer BR Challoner D Charizanos RP Ray, Dev Biol 2008 313 519 32 10.1016/j.ydbio.2007.09. 044 18093579
26. Gal4 in the Drosophila female germline. P Rorth, Mech Dev 1998 78 113 8 10.1016/S0925-4773(98)00157-9 9858703
27. Population history and natural selection shape patterns of genetic variation in 132 genes. JM Akey MA Eberle MJ Rieder CS Carlson MD Shriver DA Nickerson L Kruglyak, PLoS Biol 2004 2 e286 15361935 10.1371/journal.pbio. 0020286
28. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. B Ewing L Hillier MC Wendl P Green, Genome Res 1998 8 175 85 9521921
29. Base-calling of automated sequencer traces using phred. II. Error probabilities. B Ewing P Green, Genome Res 1998 8 186 94 9521922
30. Consed: a graphical tool for sequence finishing. D Gordon C Abajian P Green, Genome Res 1998 8 195 202 9521923
31. Automated finishing with autofinish. D Gordon C Desmarais P Green, Genome Res 2001 11 614 25 11282977 10.1101/gr.171401
32. Automating resequencing-based detection of insertion-deletion polymorphisms. TR Bhangale M Stephens DA Nickerson, Nat Genet 2006 38 1457 62 10.1038/ng1925 17115056