Treatment of an acquired factor VIII inhibitor with sequential recombinant factor VIIa and FEIBA

Haemophilia

Volumn 15, Issue 1, 2009, Pages 383-385

  Miranda, George G ^a,c   Rodgers, G M ^a,b  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; BLOOD CLOTTING FACTOR 8 INHIBITOR; HEPARIN; PREDNISONE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; RITUXIMAB;

ADULT; ARM EDEMA; ARTICLE; CASE REPORT; COMPARTMENT SYNDROME; DEBRIDEMENT; DEEP VEIN THROMBOSIS; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSPNEA; EPISTAXIS; ERYTHROCYTE TRANSFUSION; FASCIOTOMY; HEMOGLOBINOPATHY; HEMOSTASIS; HUMAN; LABORATORY TEST; MALE; PARESTHESIA; PARTIAL THROMBOPLASTIN TIME; PNEUMONIA; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; THROMBIN TIME;

BLOOD COAGULATION FACTORS; DRUG THERAPY, COMBINATION; FACTOR VIIA; FACTOR VIII; HEMOPHILIA A; HUMANS; ISOANTIBODIES; MALE; MIDDLE AGED; RECOMBINANT PROTEINS;

EID: 63049121909     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/j.1365-2516.2008.01869.x     Document Type: Article

References (5)

1. Schneiderman J, Nugent DJ, Young G. Sequential Therapy with activated prothrombin complex concentrate and recombinant factor VIIa in patients with severe haemophilia and inhibitors. Haemophilia 2004; 10: 347-51.
2. Schneiderman J, Rubin E, Nugent DJ, Young G. Haemophilia 2007; 13: 244-8.
3. Key NS, Christie B, Henderson N, Nelsestuen GL. Possible synergy between recombinant factor VIIa and prothrombin complex concentrate in hemophilia therapy. Thromb Haemost 2002; 88: 60-5.
4. Ng HJ, Loh YSM, Tan DCL, Lee LH. Thrombosis associated with the use of recombinant activated factor VII: Profiling two events. Thromb Haemost 2004; 92: 1448-9.
5. Rosenfeld SB, Watkinson KK, Thompson BH, Macfarlane DE, Lentz SR. Pulmonary embolism after sequential use of recombinant factor VIIa and activated prothrombin complex concentrate in a factor VIII inhibitor patient. Thromb Haemost 2002; 87: 925-6.