Mechanism of microthrombosis in HUS

Kidney International

Volumn 75, Issue SUPPL. 112, 2009, Pages

  Rock, Gail A ^a,c   Clark, William F ^a,b  

^a Canadian Apheresis Group   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c NONE   (Canada)

Author keywords

Anti CD36 antibodies; Hemolytic uremic syndrome; Microthrombosis; Molecular mimicry; Verotoxin

Indexed keywords

ADENOSINE TRIPHOSPHATE; CD36 ANTIGEN; CROSS REACTING ANTIBODY; VEROTOXIN 2; VON WILLEBRAND FACTOR; AUTOANTIBODY;

ADULT; BLOOD SAMPLING; CONFERENCE PAPER; ENZYME RELEASE; HEMOLYTIC UREMIC SYNDROME; HUMAN; HUMAN TISSUE; IMMUNOPATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE AGGREGATION; THROMBOSIS; WESTERN BLOTTING; ANTIBODY SPECIFICITY; ARTICLE; BLOOD; CHILD; CROSS REACTION; IMMUNOLOGY; METABOLISM; MICROVASCULATURE; MOLECULAR MIMICRY; THROMBOCYTE;

ADENOSINE TRIPHOSPHATE; ADULT; ANTIBODY SPECIFICITY; ANTIGENS, CD36; AUTOANTIBODIES; BLOOD PLATELETS; CHILD; CROSS REACTIONS; HEMOLYTIC-UREMIC SYNDROME; HUMANS; MICROVESSELS; MOLECULAR MIMICRY; PLATELET AGGREGATION; SHIGA TOXIN 2; THROMBOSIS;

EID: 63049101986     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2008.611     Document Type: Conference Paper

References (6)

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3. Rock G, Decary F, Tittley P et al. Electroblotting and immunohistochemical staining for identification of platelet antibodies. Br J Haematol 1987; 67: 437-441.
4. Rock G, Chauhan K, Jamieson GA et al. Anti-CD36 antibodies in patients with lupus anticoagulant and thrombotic complications. Br J Haematol 1994; 88: 878-880.
5. Tsai HM, Lian ECY. Antibodies to Von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura. N Engl J Med 1998; 339: 1585-1594.
6. Rock G, Mackenzie A, Hashemie S. Verotoxin-induced release of vWF and production of tissue factor by human endothelial cells. Blood 1988; 72: 308a.