Management and investigation of neonatal thromboembolic events: Genetic and acquired risk factors

Thrombosis Research

Volumn 123, Issue 6, 2009, Pages 805-809

  Saracco, P ^a   Parodi, E ^a   Fabris, C ^a   Cecinati, V ^c   Molinari, A C ^b   Giordano, P ^c  

^a UNIVERSITY OF TURIN   (Italy)

^b Dipartimento di Ematologia e Oncologia   (Italy)

^c UNIVERSITY OF BARI   (Italy)

Author keywords

Maternal; Newborn; Risk factors; Stroke; Thrombophilia; Thrombosis

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

ARTERY THROMBOSIS; CATHETER THROMBOSIS; CEREBROVASCULAR ACCIDENT; GENETIC POLYMORPHISM; GENETIC RISK; HEMOSTASIS; HUMAN; INCIDENCE; INHERITANCE; INTRACARDIAC THROMBOSIS; ISCHEMIC PERINATAL STROKE; KIDNEY VEIN THROMBOSIS; LUNG EMBOLISM; MATERNAL CARE; MATERNAL DISEASE; NEWBORN DISEASE; OCCLUSIVE CEREBROVASCULAR DISEASE; PERINATAL PERIOD; PORTAL VEIN THROMBOSIS; PREECLAMPSIA; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SCREENING; THROMBOCYTOSIS; THROMBOEMBOLISM; THROMBOPHILIA; VEIN THROMBOSIS;

CENTRAL NERVOUS SYSTEM DISEASES; FEMALE; HEMOSTASIS; HUMANS; INFANT, NEWBORN; MATERNAL-FETAL EXCHANGE; PREGNANCY; RISK FACTORS; THROMBOEMBOLISM; THROMBOPHILIA; THROMBOSIS;

EID: 63049092699     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2008.12.002     Document Type: Review

References (51)

1. Schmidt B., and Andrew M. Neonatal thrombosis: report of a prospective Canadian and international registry. Pediatrics 96 5 Pt 1 (Nov 1995) 939-943
2. Andrew M. Developmental hemostasis: relevance to hemostatic problems during childhood. Semin Thromb Hemost 21 4 (1995) 341-356
3. Andrew M., David M., Adams M., Ali K., Anderson R., Barnard D., et al. Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE. Blood 83 5 (Mar 1 1994) 1251-1257
4. van Ommen C.H., Heijboer H., Buller H.R., Hirasing R.A., Heijmans H.S., and Peters M. Venous thromboembolism in childhood: a prospective two-year registry in The Netherlands. J Pediatr 139 5 (Nov 2001) 676-681
5. Nowak-Gottl U., von Kries R., and Gobel U. Neonatal symptomatic thromboembolism in Germany: two year survey. Arch Dis Child Fetal Neonatal Ed 76 3 (May 1997) F163-F167
6. Andrew M., Paes B., Milner R., Johnston M., Mitchell L., Tollefsen D.M., et al. Development of the human coagulation system in the full-term infant. Blood 70 1 (Jul 1987) 165-172
7. Andrew M., Paes B., Milner R., Johnston M., Mitchell L., Tollefsen D.M., et al. Development of the human coagulation system in the healthy premature infant. Blood 72 5 (Nov 1988) 1651-1657
8. Andrew M., Paes B., and Johnston M. Development of the hemostatic system in the neonate and young infant. Am J Pediatr Hematol Oncol 12 1 (Spring 1990) 95-104
9. Williams M.D., Chalmers E.A., and Gibson B.E. The investigation and management of neonatal haemostasis and thrombosis. Br J Haematol 119 2 (Nov 2002) 295-309
10. Khan S., and Dickerman J.D. Hereditary thrombophilia. Thromb J 4 (2006) 15
11. Nowak-Gottl U., Junker R., Hartmeier M., Koch H.G., Munchow N., Assmann G., et al. Increased lipoprotein(a) is an important risk factor for venous thromboembolism in childhood. Circulation 100 7 (Aug 17 1999) 743-748
12. Nowak-Gottl U., Strater R., Heinecke A., Junker R., Koch H.G., Schuierer G., et al. Lipoprotein (a) and genetic polymorphisms of clotting factor V, prothrombin, and methylenetetrahydrofolate reductase are risk factors of spontaneous ischemic stroke in childhood. Blood 94 11 (Dec 1 1999) 3678-3682
13. von Depka M., Nowak-Gottl U., Eisert R., Dieterich C., Barthels M., Scharrer I., et al. Increased lipoprotein (a) levels as an independent risk factor for venous thromboembolism. Blood 96 10 (Nov 15 2000) 3364-3368
14. Adams-Chapman I., Vaucher Y.E., Bejar R.F., Benirschke K., Baergen R.N., and Moore T.R. Maternal floor infarction of the placenta: association with central nervous system injury and adverse neurodevelopmental outcome. J Perinatol 22 3 (Apr-May 2002) 236-241
15. Burke C.J., and Tannenberg A.E. Prenatal brain damage and placental infarction-an autopsy study. Dev Med Child Neurol 37 6 (Jun 1995) 555-562
16. Redline R.W., Wilson-Costello D., Borawski E., Fanaroff A.A., and Hack M. Placental lesions associated with neurologic impairment and cerebral palsy in very low-birth-weight infants. Arch Pathol Lab Med 122 12 (Dec 1998) 1091-1098
17. Clark P. Changes of hemostasis variables during pregnancy. Semin Vasc Med 3 1 (Feb 2003) 13-24
18. Golomb M.R. The contribution of prothrombotic disorders to peri- and neonatal ischemic stroke. Semin Thromb Hemost 29 4 (Aug 2003) 415-424
19. Heilmann L., von Tempelhoff G.F., and Pollow K. Antiphospholipid syndrome in obstetrics. Clin Appl Thromb Hemost 9 2 (Apr 2003) 143-150
20. Raju T.N., Nelson K.B., Ferriero D., and Lynch J.K. Ischemic perinatal stroke: summary of a workshop sponsored by the National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and Stroke. Pediatrics 120 3 (Sep 2007) 609-616
21. de Veber G. Canadian pediatric ischaemic stroke registry: analysis of children with arterial ischemic stroke. The Canadian Pediatric Stroke Group. Ann Neurol 48 (2000) 526
22. Chalmers E.A. Perinatal stroke-risk factors and management. Br J Haematol 130 3 (Aug 2005) 333-343
23. Estan J., and Hope P. Unilateral neonatal cerebral infarction in full term infants. Arch Dis Child Fetal Neonatal Ed 76 2 (Mar 1997) F88-F93
24. Wu Y.W., Miller S.P., Chin K., Collins A.E., Lomeli S.C., Chuang N.A., et al. Multiple risk factors in neonatal sinovenous thrombosis. Neurology 59 3 (Aug 13 2002) 438-440
25. deVeber G., Andrew M., Adams C., Bjornson B., Booth F., Buckley D.J., et al. Cerebral sinovenous thrombosis in children. N Engl J Med 345 6 (Aug 9 2001) 417-423
26. Kurnik K., Kosch A., Strater R., Schobess R., Heller C., and Nowak-Gottl U. Recurrent thromboembolism in infants and children suffering from symptomatic neonatal arterial stroke: a prospective follow-up study. Stroke 34 12 (Dec 2003) 2887-2892
27. Gunther G., Junker R., Strater R., Schobess R., Kurnik K., Heller C., et al. Symptomatic ischemic stroke in full-term neonates: role of acquired and genetic prothrombotic risk factors. Stroke 31 10 (Oct 2000) 2437-2441
28. Mercuri E., Cowan F., Gupte G., Manning R., Laffan M., Rutherford M., et al. Prothrombotic disorders and abnormal neurodevelopmental outcome in infants with neonatal cerebral infarction. Pediatrics 107 6 (Jun 2001) 1400-1404
29. Golomb M.R., MacGregor D.L., Domi T., Armstrong D.C., McCrindle B.W., Mayank S., et al. Presumed pre- or perinatal arterial ischemic stroke: risk factors and outcomes. Ann Neurol 50 2 (Aug 2001) 163-168
30. Curry C.J., Bhullar S., Holmes J., Delozier C.D., Roeder E.R., and Hutchison H.T. Risk factors for perinatal arterial stroke: a study of 60 mother-child pairs. Pediatr Neurol 37 2 (Aug 2007) 99-107
31. Wu Y.W., March W.M., Croen L.A., Grether J.K., Escobar G.J., and Newman T.B. Perinatal stroke in children with motor impairment: a population-based study. Pediatrics 114 3 (Sep 2004) 612-619
32. Benders M.J., Groenendaal F., Uiterwaal C.S., Nikkels P.G., Bruinse H.W., Nievelstein R.A., et al. Maternal and infant characteristics associated with perinatal arterial stroke in the preterm infant. Stroke 38 6 (Jun 2007) 1759-1765
33. Fitzgerald K.C., Williams L.S., Garg B.P., Carvalho K.S., and Golomb M.R. Cerebral sinovenous thrombosis in the neonate. Arch Neurol 63 3 (Mar 2006) 405-409
34. Bokenkamp A., von Kries R., Nowak-Gottl U., Gobel U., and Hoyer P.F. Neonatal renal venous thrombosis in Germany between 1992 and 1994: epidemiology, treatment and outcome. Eur J Pediatr 159 1-2 (Jan-Feb 2000) 44-48
35. Kuhle S., Massicotte P., Chan A., and Mitchell L. A case series of 72 neonates with renal vein thrombosis. Data from the 1-800-NO-CLOTS Registry. Thromb Haemost 92 4 (Oct 2004) 729-733
36. Lau K.K., Stoffman J.M., Williams S., McCusker P., Brandao L., Patel S., et al. Neonatal renal vein thrombosis: review of the English-language literature between 1992 and 2006. Pediatrics 120 5 (Nov 2007) e1278-e1284
37. Ross Jr. P., Ehrenkranz R., Kleinman C.S., and Seashore J.H. Thrombus associated with central venous catheters in infants and children. J Pediatr Surg 24 3 (Mar 1989) 253-256
38. Morag I., Epelman M., Daneman A., Moineddin R., Parvez B., Shechter T., et al. Portal vein thrombosis in the neonate: risk factors, course, and outcome. J Pediatr 148 6 (Jun 2006) 735-739
39. Sanerkin N.G., Edwards P., and Jacobs J. Pulmonary thrombo-embolic phenomena in the newborn. J Pathol Bacteriol 91 2 (Apr 1966) 569-574
40. Andrew M. Arterial thromboembolic complications in pediatric patients. In: Inc. BCD, editor. Thromboembolic Complications During Infancy and Childhood. London; 2000.
41. Monagle P., Adams M., Mahoney M., Ali K., Barnard D., Bernstein M., et al. Outcome of pediatric thromboembolic disease: a report from the Canadian Childhood Thrombophilia Registry. Pediatr Res 47 6 (Jun 2000) 763-766
42. John J.B., Cron S.G., Kung G.C., and Mott A.R. Intracardiac thrombi in pediatric patients: presentation profiles and clinical outcomes. Pediatr Cardiol 28 3 (May-Jun 2007) 213-220
43. Marsh D., Wilkerson S.A., Cook L.N., and Pietsch J.B. Right atrial thrombus formation screening using two-dimensional echocardiograms in neonates with central venous catheters. Pediatrics 81 2 (Feb 1988) 284-286
44. Berman Jr. W., Fripp R.R., Yabek S.M., Wernly J., and Corlew S. Great vein and right atrial thrombosis in critically ill infants and children with central venous lines. Chest 99 4 (Apr 1991) 963-967
45. Manco-Jhonson M.J., Sifontes M., and Nuss R. Coagulation abnormalities in neonatal catheter related thrombosis. Thromb Haemost 82 suppl (1999) 384
46. Nowak-Gottl U., Dubbers A., Kececioglu D., Koch H.G., Kotthoff S., Runde J., et al. Factor V Leiden, protein C, and lipoprotein (a) in catheter-related thrombosis in childhood: a prospective study. J Pediatr 131 4 (Oct 1997) 608-612
47. Revel-Vilk S., Chan A., Bauman M., and Massicotte P. Prothrombotic conditions in an unselected cohort of children with venous thromboembolic disease. J Thromb Haemost 1 5 (May 2003) 915-921
48. Kosch A., Kuwertz-Broking E., Heller C., Kurnik K., Schobess R., and Nowak-Gottl U. Renal venous thrombosis in neonates: prothrombotic risk factors and long-term follow-up. Blood 104 5 (Sep 1 2004) 1356-1360
49. Boo N.Y., Wong N.C., Zulkifli S.S., and Lye M.S. Risk factors associated with umbilical vascular catheter-associated thrombosis in newborn infants. J Paediatr Child Health 35 5 (Oct 1999) 460-465
50. Cohen R.S., Ramachandran P., Kim E.H., and Glasscock G.F. Retrospective analysis of risks associated with an umbilical artery catheter system for continuous monitoring of arterial oxygen tension. J Perinatol 15 3 (May-Jun 1995) 195-198
51. Roach E.S., Golomb M.R., Adams R., Biller J., Daniels S., deVeber G., et al. Management of Stroke in Infants and Children: A Scientific Statement From a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young. Stroke 39 9 (September 1 2008) 2644-2691