Shorter AV delays provide improved echocardiographic hemodynamics during exercise in patients receiving cardiac resynchronization therapy

PACE - Pacing and Clinical Electrophysiology

Volumn 32, Issue 4, 2009, Pages 457-465

  Grimm, Richard A ^a,c   Sun, Jing Ping ^a   Agler, Deborah ^a   Fitzgerald, Ben ^a   Wilkoff, Bruce ^a   Hilpisch, Kathryn ^b   Perlic, George ^b   Chinchoy, Edward ^b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b MEDTRONIC INC   (United States)

^c Heart and Vascular Institute ^*  (United States)

Author keywords

CRT; Echocardiography; Hemodynamics; Quality of life; Rate modulation

Indexed keywords

ADULT; ARTICLE; CARDIAC RESYNCHRONIZATION THERAPY; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; ECHOCARDIOGRAPHY; EXERCISE; FEMALE; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HEMODYNAMICS; HUMAN; MALE;

CARDIAC PACING, ARTIFICIAL; ECHOCARDIOGRAPHY; EXERCISE TEST; FEMALE; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; THERAPY, COMPUTER-ASSISTED; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 63049089345     PISSN: 01478389     EISSN: 15408159     Source Type: Journal    
DOI: 10.1111/j.1540-8159.2009.02305.x     Document Type: Article

References (21)

1. Buckingham TA, Janosik DL, Pearson AC. Pacemaker hemodynamics: Clinical implications. Prog Cardiovasc Dis 1992 34 : 347 366.
2. Greenberg B, Chatterjee K, Parmley WW, Werner JA, Holly AN. The influence of left ventricular filling pressure on atrial contribution to cardiac output. Am Heart J 1979 98 : 742 751.
3. Freedman RA, Yock PG, Echt DS, Popp RL. Effect of variation in PQ interval on patterns of atrioventricular valve motion and flow in patients with normal ventricular function. J Am Coll Cardiol 1986 7 : 595 602.
4. Leonelli FM, Wang K, Youssef M, Hall R, Brown D. Systolic and diastolic effects of variable atrioventricular delay in patients with complete heart block and normal ventricular function. Am J Cardiol 1997 80 : 294 298.
5. Nishimura RA, Hayes DL, Ilstrup DM, Holmes DR Jr., Tajik AJ. Effect of dual-chamber pacing on systolic and diastolic function in patients with hypertrophic cardiomyopathy. An acute Doppler echocardiographic and catheterization hemodynamic study. J Am Coll Cardiol 1996 27 : 421 430.
6. Ritter P, Daubert C, Mabo P, Descaves C, Gouffault J. Hemodynamic benefit of a rate adapted A-V delay in dual chamber pacing. Eur Heart J 1989 10 : 637 646.
7. Cha YM, Nishimura RA, Hayes DL. Difference in mechanical atrioventricular delay between atrial sensing and atrial pacing modes in patients with hypertrophic and dilated cardiomyopathy: An electrical hemodynamic catheterization study. J Interv Card Electrophysiol 2002 6 : 133 140.
8. Janosik DL, Pearson AC, Buckingham TA, Labovitz AJ, Redd RM. The hemodynamic benefit of differential atrioventricular delay intervals for sensed and paced atrial events during physiologic pacing. J Am Coll Cardiol 1989 14 : 499 507.
9. Frielingsdorf J, Gerber AE, Dur P, Vuilliomenet A, Bertel O. Importance of individually programmed atrioventricular delay at rest and on work capacity in patients with dual chamber pacemakers. Pacing Clin Electrophysiol 1994 17 : 37 45.
10. Stockburger M, Fateh-Moghadam S, Nitardy A, Langreck H, Haverkamp W, Dietz R. Optimization of cardiac resynchronization guided by Doppler echocardiography: Haemodynamic improvement and intraindividual variability with different pacing configurations and atrioventricular delays. Europace 2006 8 : 881 886.
11. Kerlan JE, Sawhney NS, Waggoner AD, Chawla MK, Garhwal S, Osborn JL, Faddis MN. Prospective comparison of echocardiographic atrioventricular delay optimization methods for cardiac resynchronization therapy. Pacing Clin Electrophysiol 2006 3 : 148 154.
12. Kedia N, Ng K, Apperson-Hansen C, Wang C, Tchou P, Wilkoff B, Grimm RA. Usefulness of atrioventricular delay optimization using Doppler assessment of mitral inflow in patients undergoing cardiac resynchronization therapy. Am J Cardiol 2006 98 : 780 785.
13. Khairy P, Talajic M, Dominguez M, Tardif JC, Juneau M, Lavoie L, Roy D, et al. Atrioventricular interval optimization and exercise tolerance. Pacing Clin Electrophysiol 2001 24 : 1534 1540.
14. Mehta D, Gilmour S, Ward DE, Camm AJ. Optimal atrioventricular delay at rest and during exercise in patients with dual chamber pacemakers: A non-invasive assessment by continuous wave Doppler. Br H J 1989 61 : 161 166.
15. Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E, Kocovic DZ, et al. Cardiac resynchronization in heart failure. N Engl J Med 2002 346 : 1845 1853.
16. Young JB, Abraham WT, Smith AL, Leon AR, Lieberman R, Wilkoff B, Canby RC, et al. Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure. JAMA 2003 289 : 2685 2694.
17. Sawhney NS, Waggoner AD, Garhwal S, Chalwa MK, Osborn J, Faddis MN. Randomized prospective trial of atrioventricular delay programming for cardiac resynchronization therapy. Heart Rhythm 2004 1 : 562 567.
18. Daubert C, Ritter P, Mabo P, Ollitrault J, Descaves C, Gouffault J. Physiological relationship between AV interval and heart rate in healthy subjects: Applications to dual chamber pacing. Pacing Clin Electrophysiol 1986 9 : 1032 1039.
19. Sheppard RC, Ren JF, Ross J, McAllister M, Chandrasekaran K, Kutalek SP. Doppler echocardiographic assessments of the hemodynamic benefits of rate adaptive AV delay during exercise in paced patients with complete heart block. Pacing Clin Electrophysiol 1993 16 : 2157 2167.
20. Bordachar P, Lafitte S, Reuter S, Serri K, Garrigue S, Laborderie J, Reant P, et al. Echocardiographic assessment during exercise of heart failure patients with cardiac resynchronization therapy. Am J Cardiol 2006 97 : 1622 1625.
21. Scharf C, Li P, Muntwyler J, Chugh A, Oral H, Pelosi F, Morady F, et al. Rate-dependent AV delay optimization in cardiac resynchronization therapy. Pacing Clin Electrophysiol 2005 28 : 279 284.