Extraction of amino acids by reverse iontophoresis in vivo

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 72, Issue 1, 2009, Pages 226-231

  Sieg, Anke ^a   Jeanneret, Fabienne ^b   Fathi, Marc ^c   Hochstrasser, Denis ^c   Rudaz, Serge ^d   Veuthey, Jean Luc ^d   Guy, Richard H ^e   Begona Delgado Charro M ^e  

^a Dow Corning SA Belgium   (Belgium)

^b Viollier AG   (Switzerland)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e University of Bath   (United Kingdom)

Author keywords

Amino acids; Clinical chemistry; Phenylalanine; Reverse iontophoresis; Skin; Therapeutic monitoring

Indexed keywords

ALANINE; AMINO ACID DERIVATIVE; ARGININE; ASPARTIC ACID; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HISTIDINE; ISOLEUCINE; LYSINE; PHENYLALANINE; PROLINE; SERINE; THREONINE; TYROSINE; VALINE;

ADULT; AMINO ACID ANALYSIS; AMINO ACID TRANSPORT; ARTICLE; CONTROLLED STUDY; EXTRACTION; FEMALE; HUMAN; IN VIVO STUDY; IONTOPHORESIS; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; REVERSE IONTOPHORESIS; SKIN ABSORPTION;

ADMINISTRATION, CUTANEOUS; ADULT; AMINO ACIDS; CHEMISTRY, PHARMACEUTICAL; FEMALE; HUMANS; IONS; IONTOPHORESIS; MALE; MIDDLE AGED; PHENYLALANINE; SKIN; SKIN ABSORPTION; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS;

EID: 62949200644     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.12.012     Document Type: Article

References (22)

1. Leboulanger B., Guy R.H., and Delgado-Charro M.B. Reverse iontophoresis for non-invasive transdermal monitoring. Physiol. Meas. 25 (2004) R35-R50
2. Glikfeld P., Hinz R.S., and Guy R.H. Noninvasive sampling of biological fluids by reverse iontophoresis. Pharm. Res. 6 (1989) 988-990
3. ® Biographer: a continual, non-invasive glucose monitor for patients with diabetes. Biosens. Bioelectron. 16 (2001) 621-629
4. Leboulanger B., Guy R.H., and Delgado-Charro M.B. Non-invasive lithium monitoring by reverse iontophoresis. An in vivo study. Clin. Chem. 50 (2004) 2091-2100
5. Leboulanger B., Guy R.H., and Delgado-Charro M.B. Non-invasive monitoring of phenytoin by reverse iontophoresis. Eur. J. Pharm. Sci. 22 (2004) 427-433
6. Delgado-Charro M.B., and Guy R.H. Transdermal reverse iontophoresis of valproate: a non-invasive method for therapeutic drug monitoring. Pharm. Res. 20 (2003) 1508-1513
7. Nixon S., Sieg A., Delgado-Charro M.B., and Guy R.H. Reverse iontophoresis of l-lactate: in vitro and in vivo studies. J. Pharm. Sci. 96 (2007) 3457-3465
8. Wascotte V., Delgado-Charro M.B., Rozet E., Wallemacq P., Hubert P., Guy R.H., and Preat V. Monitoring of urea and potassium by reverse iontophoresis in vitro. Pharm. Res. 24 (2007) 1131-1137
9. Clarke J.T.R. A clinical guide to inherited metabolic diseases. second ed. (2002), Cambridge University Press, UK
10. Green P.G., Hinz R.S., Kim A., Cullander C., Yamane G., Szoka F.C., and Guy R.H. Transdermal iontophoresis of amino acids and peptides in vitro. J. Control. Release 21 (1992) 187-190
11. Shaya S.Y., Smith C.W., and Heathcote J.G. Percutaneous electrophoresis of amino acids and urea. Med. Biol. Eng. Comput. 16 (1978) 126-134
12. Merino V., Lopez A., Hochstrasser D., and Guy R.H. Noninvasive sampling of phenylalanine by reverse iontophoresis. J. Control. Release 61 (1999) 65-69
13. Longo N., Li S.K., Yan G., Kochambilli R.P., Papangkorn K., Berglund D., et al. Noninvasive measurement of phenylalanine by iontophoretic extraction in patients with phenylketonuria. J. Inherit. Metab. Dis. 30 (2007) 910-915
14. Phipps J.B., and Goyry J.R. Transdermal ion migration. Adv. Drug Deliv. Rev. 9 (1992) 137-176
15. Burnette R.R., and Ongpipanattakul B. Characterization of permselective properties of excised human skin during iontophoresis. J. Pharm. Sci. 76 (1987) 765-773
16. Pikal M.J. The role of electroosmotic flow in transdermal iontophoresis. Adv. Drug Deliv. Rev. 9 (1992) 201-237
17. Sieg A., Jeanneret F., Fathi M., Hochstrasser D., Rudaz S., Veuthey J.L., Guy R.H., and Delgado-Charro M.B. Extraction of amino acids by reverse iontophoresis: simulation of therapeutic monitoring in vitro. Eur. J. Pharm. Biopharm. 70 (2008) 908-913
18. Chaimbault P., Petritis K., Elfakir C., and Dreux M. Determination of 20 underivatized proteinic amino acids by ion-pairing chromatography and pneumatically assisted electrospray mass spectrometry. J. Chromatogr. A 855 (1999) 191-202
19. Petritis K., Chaimbault P., Elfakir C., and Dreux M. Ion-pair reversed-phase liquid chromatography for determination of polar underivatized amino acids using perfluorinated carboxylic acids as ion pairing agent. J. Chromatogr. A 833 (1999) 147-155
20. F. Jeanneret, Etude du liquide interstitial cutané comme matrice alternative lors de suivi thérapeutique: couplage LC-MS pour l'analyse des acides amines extraits par ionophorèse inverse in vitro et in vivo, PhD thesis, University of Geneva, Switzerland, 2004.
21. Lee P.L., and Slocum R.H. A high-resolution method for amino acid analysis of physiological fluids containing mixed disulfides. Clin. Chem. 34 (1988) 719-723
22. Rawlings A.V., Scott I.R., Harding C.R., and Bowser P.A. Stratum corneum moisturization at the molecular level. J. Invest. Dermatol. 116 (1994) 731-740