Establishment of lethal inhalational infection with Francisella tularensis (tularaemia) in the common marmoset (Callithrix jacchus)

International Journal of Experimental Pathology

Volumn 90, Issue 2, 2009, Pages 109-118

  Nelson, Michelle ^a   Lever, Mark S ^a   Savage, Victoria L ^a   Salguero, Francisco Javier ^b   Pearce, Peter C ^a   Stevens, Daniel J ^a   Simpson, Andrew J H ^a  

^a DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

Francisella tularensis; Inhalation; Marmoset; Tularaemia

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BACTERIAL PNEUMONIA; BRONCHOPNEUMONIA; COLONY FORMING UNIT; CONTROLLED STUDY; CORE TEMPERATURE; DISEASE COURSE; DISEASE SEVERITY; EXPERIMENTAL MODEL; FEMALE; FRANCISELLA TULARENSIS; HEPATITIS; HISTOPATHOLOGY; INFECTION SENSITIVITY; LD 50; LIVER DISEASE; LIVER GRANULOMA; LUNG DISEASE; LYMPHADENITIS; MALE; MARMOSET; NONHUMAN; PRIORITY JOURNAL; SPLEEN DISEASE; TULAREMIA;

ANIMALS; CALLITHRIX; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DISEASE SUSCEPTIBILITY; FEMALE; FRANCISELLA TULARENSIS; INHALATION EXPOSURE; KIDNEY; LETHAL DOSE 50; LIVER; LUNG; MALE; PNEUMONIA, BACTERIAL; SPLEEN; TULAREMIA; VIRULENCE;

EID: 62949163840     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.1365-2613.2008.00631.x     Document Type: Article

References (32)

1. Avery F.W. Barnett T.B. (1966) Pulmonary tularemia. Am. Rev. Respir. Dis. 95, 584 591.
2. Baskerville A., Hambleton P., Dowsett A.B. (1978) The pathology of untreated and antibiotic-treated experimental tularaemia in monkeys. Br. J. Exp. Pathol. 59, 615 623.
3. CDC (2008) CDC Emergency Preparedness and Response website, Bioterrorism Agents/Diseases, by Category. Available at: http://emergency.cdc.gov/agent/ agentlist-category.asp accessed on 19 June 2008.
4. Chen W., Shen H., Webb A., KuoLee R., Conlan J.W. (2003) Tularemia in BALB/c and C57BL/6 mice vaccinated with Francisella tularensis LVS and challenged intradermally, or by aerosol with virulent isolates of the pathogen: protection varies depending on pathogen virulence, route of exposure, and host genetic background. Vaccine 2125-26, 3690 3700.
5. Cho W.-S. Chae C. (2003) Expression of cyclooxygenase-2 in swine naturally infected with Actinobacillus pleuropneumoniae. Vet. Pathol. 40, 25 31.
6. Conlan J.W., Chen W., Shen H., Webb A., KuoLee R. (2003) Experimental tularemia in mice challenged by aerosol or intradermally with virulent strains of Francisella tularensis: bacteriologic and histopathologic studies. Microb. Pathog. 34, 239 248.
7. Day W.C. Berendt R.F. (1972) Experimental tularemia in Macaca mulatta: relationship of aerosol particle size to the infectivity of airborne Pasteurella tularensis. Infect. Immun. 5, 77 82.
8. Dennis D.T., Inglesby T.V., Henderson D.A., et al. (2001) Tularaemia as a biological weapon - medical and public health management. JAMA 285, 2763 2773.
9. Dixon W.J. Fotheringham N. (1993) Application of staircase bioassays in pharmaceutical research. Drug Inf. J. 27, 741 751.
10. Druett H.A. (1969) A mobile form of the Henderson apparatus. J. Hyg. 67, 437 448.
11. Eigelsbach H.T., Tulis J.J., McGavran M.H., White J.D. (1962) Live tularaemia vaccine 1. Host-parasite relationship in monkeys vaccinated intra-cutaneously or aerogenically. J. Bacteriol. 84, 1020 1027.
12. Ellis J., Oyston P.C., Green M., Titball R.W. (2002) Tularaemia. Clin. Microbiol. Rev. 15, 631 646.
13. Evan M.E., Gregory D.W., Schaffner W., McGee Z.A. (1985) Tularemia: a 30-year experience with 88 cases. Medicine (Baltimore) 64, 251 269.
14. Finegold M.J., Petery J.J., Berendt R.F., Adams H.R. (1968) Studies on the pathogenesis of plague. Blood coagulation and tissue responses of Macaca mulatta following exposure to aerosols of Pasteurella pestis. Am. J. Pathol. 53, 99 114.
15. Hall W.C., Kovatch R.M., Schricker R.L. (1973) Tularaemic pneumonia: pathogenesis of the aerosol-induced disease in monkeys. J. Pathol. 110, 193 201.
16. Hetherington C.M. (1978) Circadian oscillations of body temperature in the marmoset, Callithrix jacchus. Lab. Anim. 12, 107 108.
17. Lamps L.W., Havens J.M., Sjostedt A., Page D.L., Scott M.A. (2004) Histologic and molecular diagnosis of tularemia: a potential bioterrorism agent endemic to North America. Mod. Pathol. 17, 489 495.
18. Lever M.S., Stagg A.J., Nelson M. et al. (2008) Experimental respiratory anthrax infection in the common marmoset (Callithrix jacchus). Int. J. Exp. Pathol. 89, 171 179.
19. Lyons R.C. Wu T.H. (2007) Animal models of Francisella tularensis infection. Ann. N. Y. Acad. Sci. 1105, 238 265.
20. Mann T.M., Williams K.E., Pearce P.C., Scott E.A.M. (2005) A novel method for activity monitoring in small non-human primates. Lab. Anim. 39, 169 177.
21. Martin G.M. Marty A.M. (2001) Clinicopathologic aspects of bacterial agents. Clin. Lab. Med. 21, 513 548.
22. Posthaus H., Welle M., Morner T., Nicolet J., Kuhnert P. (1998) Tularemia in a common marmoset (Callithrix jacchus) diagnosed by 16S rRNA sequencing. Vet. Microbiol. 61, 145 150.
23. Saslaw S., Eigelsbach H.T., Prior J.A., Wilson H.E., Carhart S. (1961) Tularemia vaccine study. II. Respiratory challenge. Arch. Intern. Med. 107, 702 714.
24. Sawyer W.D., Dangerfield H.G., Hogge A.L., Crozier D. (1966) Antibiotic prophylaxis and therapy of airborne tularemia. Bacteriol. Rev. 30, 542 550.
25. Schricker R.L., Eigelsbach H.T., Mitten J.Q., Hall W.C. (1972) Pathogenesis of tularemia in monkeys aerogenically exposed to Francisella tularensis 425. Infect. Immun. 5, 734 744.
26. Sjostedt A., Conlan J.W., North R.J. (1994) Neutrophils are critical for host defense against primary infection with the facultative intracellular bacterium Francisella tularensis in mice and participate in defense against reinfection. Infect. Immun. 62, 2779 2783.
27. Splettstoesser W.D., Mätz-Rensing K., Seibold E. et al. (2007) Re-emergence of Francisella tularensis in Germany: fatal tularaemia in a colony of semi-free-living marmosets (Callithrix jacchus). Epidemiol. Infect. 135, 1256 1265.
28. Stuart B.M. Pullen R.L. (1945) Tularemic pneumonia. Review of American literature and report of 15 additional cases. Am. J. Med. Sci. 210, 223.
29. Syrjala H., Sutinene S., Jokinen K., Nieminen P., Tuuponen T., Salminen A. (1986) Bronchial changes in airborne tularemia. J. Laryngol. Otol. 100, 1169 1176.
30. Tulis J.J., Eigelsbach H.T., Hornick R.B. (1969) Oral vaccination against tularemia in the monkeys. Proc. Soc. Exp. Biol. Med. 132, 893 897.
31. Tulis J.J., Eigelsbach H.T., Kerpsack R.W. (1970) Host-parasite relationship in monkeys administered live tularemia vaccine. Am. J. Pathol. 58, 329 336.
32. Williamson E.D., Savage V.L., Lingard B., Russell P., Scott E.A.M. (2007) A biocompatible microdevice for core body temperature monitoring in the early diagnosis of infectious diseases. Biomed. Microdevices 9, 51 60.