Ultrastructural immunolocalization of a cartilage-specific proteoglycan, aggrecan, in salivary pleomorphic adenomas

Medical Molecular Morphology

Volumn 42, Issue 1, 2009, Pages 47-54

  Muramatsu, Koji ^a   Kusafuka, Kimihide ^a   Watanabe, Hideto ^b   Mochizuki, Toru ^a   Nakajima, Takashi ^a  

^a SHIZUOKA CANCER CENTER   (Japan)

^b AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Aggrecan; Immunoelectron microscopy; Pheomorphic adenoma; Salivary gland; Ultrastructure

Indexed keywords

AGGRECAN; PROTEOGLYCAN;

ADULT; AGED; ARTICLE; CANCER CELL; CARTILAGE; CELL VACUOLE; CLINICAL ARTICLE; ENZYME LOCALIZATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; MALE; MYOEPITHELIUM CELL; PAROTID GLAND; PLEOMORPHIC ADENOMA; PRIORITY JOURNAL; SALIVARY GLAND TUMOR; SUBMANDIBULAR GLAND; TUMOR LOCALIZATION; ULTRASTRUCTURE;

ADENOMA, PLEOMORPHIC; ADULT; AGED; AGGRECANS; FEMALE; HUMANS; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; SALIVARY GLAND NEOPLASMS; VACUOLES; YOUNG ADULT;

EID: 62949159459     PISSN: 18601480     EISSN: 18601499     Source Type: Journal    
DOI: 10.1007/s00795-008-0429-4     Document Type: Article

References (17)

1. I. Dardick A.W.P. Van Nostrand M.T.D. Jeans P. Rippstein V. Edwards 1983 Pleomorphic adenoma. II. Ultrastructural organization of "stromal regions." Hum Pathol 14 798 809
2. R.A. Erlandson C. Cardon-Cardo P.J. Higgins 1984 Histogenesis of benign pleomorphic adenomas (mixed tumor) of the major salivary glands. An ultrastructural and immunohistochemical study Am J Surg Pathol 8 803 820
3. S. Morinaga T. Nakajima Y. Shimosato 1987 Normal and neoplastic myoepithelial cells in salivary glands: an immunohistochemical study Hum Pathol 18 1218 1226
4. Y. Takai M. Mori I. Dardick A. MacKay R. Leung D. Wattimena H. Christensen A. Burford-Mason 1994 Myofilament localization and immunoelectron microscopic detection of muscle-specific actin in neoplastic myoepithelial cells in pleomorphic adenomas and myoepitheliomas Ultrastruct Pathol 18 575 591
5. K. Kusafuka A. Yamaguchi T. Kayano M. Fujiwara T. Takemura 1998 Expression of bone morphogenetic proteins in salivary pleomorphic adenomas Virchows Arch 432 247 253
6. K. Kusafuka A. Yamaguchi T. Kayano T. Takemura 1999 Immunohistochemical localization of the bone morphogenetic protein-6 in salivary pleomorphic adenomas Pathol Int 49 1023 1027
7. K. Kusafuka F.P. Luyten R. De Bondt Y. Hiraki C. Shukunami T. Kayano T. Takemura 2003 Immunohistochemical evaluation of cartilage-derived morphogenetic protein-1 and -2 in normal human salivary glands and pleomorphic adenomas Virchows Arch 442 482 490
8. K. Kusafuka A. Yamaguchi T. Kayano T. Takemura 1998 Immunohistochemical localization of fibroblast growth factors (FGFs) and FGF receptor-1 in human normal salivary glands and pleomorphic adenomas J Oral Pathol Med 27 287 292
9. K. Kusafuka Y. Hiraki C. Shukunami A. Yamaguchi T. Kayano T. Takemura 2001 Cartilage-specific matrix protein chondromodulin-I is associated with chondroid formation in salivary pleomorphic adenomas: immunohistochemical analysis Am J Pathol 158 1465 1472
10. K. Kusafuka K. Nakano Y. Hiraki C. Shukunami H. Nagatsuka N. Nagai T. Takemura Y. Sakaguchi K. Okazaki M. Kusafuka H. Hisha S. Ikehara 2005 Expression and localization of cartilage-specific matrix protein chondromodulin-I mRNA in salivary pleomorphic adenomas Virchows Arch 446 34 40
11. W. Luo C. Guo J. Zhang T.L. Chen P.Y. Wang B.M. Vertel M.L. Tnazer 2000 Aggrecan from start to finish J Bone Miner Metab 18 51 56
12. G. Landini 1991 Immunohistochemical demonstration of type II collagen in the chondroid tissue of pleomorphic adenomas of the salivary glands Acta Pathol Jpn 41 270 276
13. M. Zhao T. Takata I. Ogawa T. Tada K. Kimata H. Nikai 1999 Immunohistochemical evaluation of the small and large proteoglycans in pleomorphic adenoma of the salivary glands J Oral Pathol Med 28 37 42
14. T.M. Murad E. von Haam 1968 Ultrastructure of myoepithelial cells human mammary gland tumors Cancer (Phila) 21 1137 1149
15. J. Takeuchi M. Sobue M. Yoshida T. Esaki Y. Kato 1975 Pleomorphic adenoma of the salivary gland. With special reference to histochemical and electron microscopic studies and biochemical analysis of glycosaminoglycans in vivo and in vitro Cancer (Phila) 36 1771 1789
16. K. Kusafuka H. Watanabe K. Kimata Y. Hiraki C. Shukunami T. Kameya 2007 Minute pleomorphic adenoma of the submandibular gland in patients with oral malignancy: a report of two cases with histological and immunohistochemical examination Histopathology (Oxf) 51 258 261
17. K. Kusafuka T. Ishiwata Y. Sugisaki T. Takemura M. Kusafuka H. Hisha S. Ikehara 2004 Lumican expression is associated with the formation of mesenchyme-like elements in salivary pleomorphic adenomas J Pathol 203 953 960