Anti-MICA Antibodies Are Related to Adverse Outcome in Heart Transplant Recipients

Journal of Heart and Lung Transplantation

Volumn 28, Issue 4, 2009, Pages 305-311

  Kauke, Teresa ^a   Kaczmarek, Ingo ^a   Dick, Andrea ^a   Schmoeckel, Michael ^a   Deutsch, Marcus Andre ^a   Beiras Fernandez, Andres ^a   Reichart, Bruno ^a   Spannagl, Michael ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; HLA A ANTIGEN; HLA ANTIBODY; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1 RELATED A ANTIBODY; UNCLASSIFIED DRUG;

ACUTE GRAFT REJECTION; ADULT; ANTIBODY DETECTION; ANTIGEN SPECIFICITY; ARTICLE; CARDIAC ALLOGRAFT VASCULOPATHY; FEMALE; GRAFT FAILURE; HEART TRANSPLANTATION; HUMAN; IMMUNOASSAY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR;

ADULT; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODY SPECIFICITY; BIOLOGICAL MARKERS; FEMALE; FOLLOW-UP STUDIES; GENOTYPE; GRAFT REJECTION; HEART TRANSPLANTATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MALE; MIDDLE AGED; REOPERATION; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; SURVIVORS; TIME FACTORS;

EID: 62949154895     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healun.2009.01.003     Document Type: Article

References (25)

1. Reed E.F., Demetris A.J., Hammond E., et al. Acute antibody-mediated rejection of cardiac transplants. J Heart Lung Transplant 25 (2006) 153-159
2. Rahmani M., Cruz R.P., Granville D.J., and McManus B.M. Allograft vasculopathy versus atherosclerosis. Circ Res 99 (2006) 801-815
3. Patel R., and Terasaki P.I. Significance of the positive crossmatch test in kidney transplantation. N Engl J Med 280 (1969) 735-739
4. Kaczmarek I., Deutsch M.A., Sadoni S., et al. Successful management of antibody-mediated cardiac allograft rejection with combined immunoadsorption and anti-CD20 monoclonal antibody treatment: case report and literature review. J Heart Lung Transplant 26 (2007) 511-515
5. Terasaki P.I. Humoral theory of transplantation. Am J Transplant 3 (2003) 665-673
6. Mizutani K., Terasaki P., Rosen A., et al. Serial ten-year follow-up of HLA and MICA antibody production prior to kidney graft failure. Am J Transplant 5 (2005) 2265-2272
7. Stastny P., Lavingia B., Fixler D.E., Yancy C.W., and Ring W.S. Antibodies against donor human leukocyte antigens and the outcome of cardiac allografts in adults and children. Transplantation 84 (2007) 738-745
8. Mizutani K., Terasaki P.I., Shih R.N., Pei R., Ozawa M., and Lee J. Frequency of MIC antibody in rejected renal transplant patients without HLA antibody. Hum Immunol 67 (2006) 223-229
9. Rose M.L. De novo production of antibodies after heart or lung transplantation should be regarded as an early warning system. J Heart Lung Transplant 23 (2004) 385-395
10. Zwirner N.W., Marcos C.Y., Mirbaha F., Zou Y., and Stastny P. Identification of MICA as a new polymorphic alloantigen recognized by antibodies in sera of organ transplant recipients. Hum Immunol 61 (2000) 917-924
11. Carter V., Shenton B.K., Jaques B., et al. Vimentin antibodies: a non-HLA antibody as a potential risk factor in renal transplantation. Transplant Proc 37 (2005) 654-657
12. Dragun D., Muller D.N., Brasen J.H., et al. Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med 352 (2005) 558-569
13. Glotz D., Lucchiari N., Pegaz-Fiornet B., and Suberbielle-Boissel C. Endothelial cells as targets of allograft rejection. Transplantation 82 1 suppl (2006) S19-S21
14. Suarez-Alvarez B., Lopez-Vazquez A., Gonzalez M.Z., et al. The relationship of anti-MICA antibodies and MICA expression with heart allograft rejection. Am J Transplant 7 (2007) 1842-1848
15. Zhang Y., and Stastny P. MICA antigens stimulate T cell proliferation and cell-mediated cytotoxicity. Hum Immunol 67 (2006) 215-222
16. Mizutani K., Terasaki P., Bignon J.D., et al. Association of kidney transplant failure and antibodies against MICA. Hum Immunol 67 (2006) 683-691
17. Zou Y., Heinemann F.M., Grosse-Wilde H., et al. Detection of anti-MICA antibodies in patients awaiting kidney transplantation, during the post-transplant course, and in eluates from rejected kidney allografts by Luminex flow cytometry. Hum Immunol 67 (2006) 230-237
18. Sumitran-Karuppan S., Tyden G., Reinholt F., Berg U., and Moller E. Hyperacute rejections of two consecutive renal allografts and early loss of the third transplant caused by non-HLA antibodies specific for endothelial cells. Transpl Immunol 5 (1997) 321-327
19. Morgun A., Shulzhenko N., Unterkircher C.S., et al. Pre- and post-transplant anti-myosin and anti-heat shock protein antibodies and cardiac transplant outcome. J Heart Lung Transplant 23 (2004) 204-209
20. Sumitran-Holgersson S., Wilczek H.E., Holgersson J., and Soderstrom K. Identification of the nonclassical HLA molecules, mica, as targets for humoral immunity associated with irreversible rejection of kidney allografts. Transplantation 74 (2002) 268-277
21. Zou Y., Stastny P., Susal C., Dohler B., and Opelz G. Antibodies against MICA antigens and kidney-transplant rejection. N Engl J Med 357 (2007) 1293-1300
22. Suarez-Alvarez B., Lopez-Vazquez A., az-Pena R., et al. Post-transplant soluble MICA and MICA antibodies predict subsequent heart graft outcome. Transpl Immunol 17 (2006) 43-46
23. Suarez-Alvarez B., Lopez-Vazquez A., az-Molina B., et al. The predictive value of soluble major histocompatibility complex class I chain-related molecule A (MICA) levels on heart allograft rejection. Transplantation 82 (2006) 354-361
24. Stoica S.C., Cafferty F., Pauriah M., et al. The cumulative effect of acute rejection on development of cardiac allograft vasculopathy. J Heart Lung Transplant 25 (2006) 420-425
25. Smith J.D., Hamour I.M., Banner N.R., and Rose M.L. C4d fixing, luminex binding antibodies - a new tool for prediction of graft failure after heart transplantation. Am J Transplant 7 (2007) 2809-2815