Use of specific serotonin reuptake inhibitors (SSRIs) (Sertraline or Citalopram) in the treatment of depression reduces the cardiovascular risk in the elderly: Evidence from a Sicilian population >80 years recovered in the assisted sanitary residences (RSA)

Archives of Gerontology and Geriatrics

Volumn 48, Issue 3, 2009, Pages 350-352

  Santangelo, Antonino ^a,b   Testaì, Manuela ^a   Barbagallo, Patrizia ^b   Crisafulli, Cristiano ^b   Grasso, Sebastiano ^a   Manuele, Sara ^a   Muscarà, Giuliana ^b   Rizzotto, Maurizio ^a   Tomarchio, Marcello ^c   Maugeri, Domenico ^a  

^a Dipartimento Scienze della Senescenza   (Italy)

^b RSA Residence Futura   (Italy)

^c SISIFO Consorzio Cooperative Sociali   (Italy)

Author keywords

Citalopram; Depression and cardiovascular pathologies in elderly; Sertraline; Treatment with SSRIs

Indexed keywords

CITALOPRAM; SERTRALINE;

AGED; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CONVALESCENCE; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DRUG USE; ELDERLY CARE; FEMALE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK REDUCTION; TREATMENT DURATION; TREATMENT RESPONSE;

ACTIVITIES OF DAILY LIVING; AGED, 80 AND OVER; CARDIOVASCULAR DISEASES; CITALOPRAM; DEPRESSION; FEMALE; HOMES FOR THE AGED; HUMANS; MALE; RISK; SEROTONIN UPTAKE INHIBITORS; SERTRALINE; SICILY;

EID: 62949133636     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archger.2008.02.014     Document Type: Article

References (38)

1. American Psychiatric Association (APA), 1994. Diagnostic and Statistical Manual of Mental Disorders. 4th ed.: DSM IV. APA Press, Washington, USA.
2. Ballard C.G., and Bannister C. Oyebode depression in dementia sufferers. Int. J. Geriatr. Psychiatry 11 (1996) 507-515
3. Bär K.J., Greiner W., Jochum T., Friedrich M., Wagner G., and Sauer H. The influence of major depression and its treatment on heart rate variability and pupillary light reflex parameters. J. Affect. Disord. 82 (2004) 245-252
4. Barnes D.E., Alexopoulos G.S., Lopez O.L., Williamson J.D., and Yaffe K. Depressive symptoms, vascular disease, and mild cognitive impairment: findings from the Cardiovascular Health Study. Arch. Gen. Psychiatry 63 (2006) 273-279
5. Bekelman D.B., Havranek E.P., Becker D.M., Kutner J.S., Peterson P.N., Wittstein I.S., Gottlieb S.H., Yamashita T.E., Fairclough D.L., and Dy S.M. Symptoms, depression, and quality of life in patients with heart failure. J. Card. Fail. 13 (2007) 643-648
6. Bianchetti A., and Trabucchi M. Gli outcome della cure delle demenze. In: Zanetti E. (Ed). La sfida della qualita nell'assistenza agli anziani (1997), Lauri Ed, Milano 117-126 (in Italian)
7. Bianchetti A., and Zanetti O. La valutazione funzionale dell'anziano. Quale salute per l'anziano del terzo millennio? (1994), Gruppo di Ricerca Geriatrica, Brescia pp. 47-59 (in Italian)
8. Bianchetti A., Rozzini R., and Trabucchi M. Demenze. In: De Leo D., and Stella A. (Eds). Manuale di psichiatria dell'anziano (1994), Piccin Ed, Padova 343-371 (in Italian)
9. Booij L., Swenne C.A., Brosschot J.F., Haffmans P.M., Thayer J.F., and Van der Does A.J. Tryptophan depletion affects heart rate variability and impulsivity in remitted depressed patients with a history of suicidal ideation. Biol. Psychiatry 4 (2006) 139-145
10. Christensen H., Henderson A.S., Jorm A.F., Mackinnon A.J., Scott R., and Korten A.E. ICD-10 mild cognitive disorder: epidemiological evidence on its validity. Psychol. Med. 25 (1995) 105-120
11. Csef H., and Hefner J. Psychosocial stress as a risk- and prognostic factor in coronary artery disease and myocardial infarction. Versicherungsmedizin 58 (2006) 3-8 (in German)
12. Das S., and O'Keefe J.H. Behavioral cardiology: recognizing and addressing the profound impact of psychosocial stress on cardiovascular health. Curr. Atheroscler. Rep. 8 (2006) 111-118
13. Emanuele E., Carlin M.V., D'Angelo A., Peros E., Barale F., Geroldi D., and Politi P. Elevated plasma levels of lipoprotein (a) in psychiatric patients: a possible contribution to increased vascular risk. Eur. Psychiatry 21 (2006) 129-133
14. Escolar G., Diaz-Ricart M., Gomez-Gil E., Serra M., Gasto C., Bozzo J., and Galan A.M. Serotonergic mechanisms: a potential link between affective disorders and cardiovascular risk. Drugs Today (Barc.) 41 (2005) 721-743
15. Folstein M.F., Folstein S.E., and McHugh P.R. Mini Mental State: a practical method for grading the cognitive state of patients for the clinician. J. Psychol. Res. 12 (1975) 189-198
16. Giltay E.J., Kamphuis M.H., Kalmijn S., Zitman F.G., and Kromhout D. Dispositional optimism and the risk of cardiovascular death: the Zutphen Elderly Study. Arch. Intern. Med. 166 (2006) 431-436
17. Guinjoan S.M., Castro M.N., Vigo D.E., Weidema H., Berbara C., Fahrer R.D., Grancelli H., Nogues M., Leiguarda R.C., and Cardinali D.P. Depressive symptoms are related to decreased low-frequency heart rate variability in older adults with decompensated heart failure. Neuropsychobiology 55 (2007) 219-224
18. Isbister G.K., Bowe S.J., Dawson A., and Whyte I.M. Relative toxicity of selective serotonin reuptake inhibitors (SSRIs) in overdose. J. Toxicol. Clin. Toxicol. 42 (2004) 277-285
19. Kamphuis M.H., Kalmijn S., Tijhuis M.A., Geerlings M.I., Giampaoli S., Nissinen A., Grobbee D.E., and Kromhout D. Depressive symptoms as risk factor of cardiovascular mortality in older European men: the Finland, Italy and Netherlands Elderly (FINE) study. Eur. J. Cardiovasc. Prev. Rehabil. 13 (2006) 199-206
20. Keller N.R., Diedrich A., Appalsamy M., Miller L.C., Caron M.G., McDonald M.P., Shelton R.C., Blakely R.D., and Robertson D. Norepinephrine transporter-deficient mice respond to anxiety producing and fearful environments with bradycardia and hypotension. Neuroscience 1 (2006) 233-238
21. Knox S., Barnes A., Kiefe C., Lewis C.E., Iribarren C., Matthews K.A., Wong N.D., and Whooley M. History of depression, race, and cardiovascular risk in CARDIA. Int. J. Behav. Med. 13 (2006) 44-50
22. Lawton M.P., and Brody E.M. Assessment of older people; self-maintaining and instrumental activities of daily living. Gerontologist 9 (1969) 179-186
23. Levy R. Aging-associated cognitive decline. Int. Psychogeriatr. 6 (1994) 63-68
24. Loucks E.B., Berkman L.F., Gruenewald T.L., and Seeman T.E. Relation of social integration to inflammatory marker concentrations in men and women 70 to 79 years. Am. J. Cardiol. 97 (2006) 1010-1016
25. Mahoney F.I., and Barthel D.W. Functional evaluation: the Barthel Index. Md. Med. J. 14 (1965) 61-65
26. Massart N., and Triffaux J.M. Depression and coronary artery disease. Rev. Med. Liege 60 (2005) 931-938
27. Murray J.B. Cardiac disorders and antidepressant medications. J. Psychol. 134 (2000) 162-168
28. Narita K., Murata T., Hamada T., Takahashi T., Omori M., Suganuma N., Yoshida H., and Wada Y. Interactions among higher trait anxiety, sympathetic activity, and endothelial function in the elderly. J. Psychiatr. Res. 41 (2006) 418-427
29. In: Osterwail D., Reuben D.B., Rozzini R., Rubenstein L.Z., and Trabucchi M. (Eds). New Frontiers in Geriatric Medicine (1993), Kendall Publisher, Padova, Italy pp. 191-213
30. Purebl G., Birkas E., Csoboth C., Szumska I., and Kopp M.S. The relationship of biological and psychological risk factors of cardiovascular disorders in a large-scale national representative community survey. Behav. Med. 31 (2006) 133-139
31. Ray W.A., Meredith S., Thapa P.B., Hall K., and Murray K.T. Cyclic anti-depressants and the risk of sudden cardiac death. Clin. Pharmacol. Ther. 75 (2004) 234-241
32. Rush A.J., and Weissen-Burger J.E. Melancholic symptom features and DSM-IV. Am. J. Psychiatry 151 (1994) 489-498
33. Rutledge T., Reis S.E., Olson M., Owens J., Kelsey S.F., Pepine C.J., Mankad S., Rogers W.J., Sopko G., Cornell C.E., Sharaf B., and Merz C.N. Depression is associated with cardiac symptoms, mortality risk, and hospitalization among women with suspected coronary disease: the NHLBI-sponsored WISE study. Psychosom. Med. 68 (2006) 217-223
34. Settle Jr. E.C. Antidepressant drugs: disturbing and potentially dangerous adverse effects. J. Clin. Psychiatry 59 Suppl. 16 (1998) 25-30
35. Tinetti M. Performance-oriented assessment of mobility problems in elderly patient. J. Am. Geriatr. Soc. 34 (1986) 119-126
36. Trabucchi, M. (Ed.), 2000. Le demenze (2nd ed.). UTET Editore, Torino (in Italian).
37. Von Kanel R., Dimsdale J.E., Ancoli-Israel S., Mills P.J., Patterson T.L., McKibbin C.L., Archuleta C., and Grant I. Poor sleep is associated with higher plasma proinflammatory cytokine interleukin-6 and procoagulant marker fibrin d-dimer in older caregivers of people with Alzheimer's disease. J. Am. Geriatr. Soc. 54 (2006) 431-437
38. Yesavage J.A., Brink T.L., Rose T.L., and Adey M. The geriatric depression rating scale: comparison with other self-report and psychiatric rating scales in assessment in geriatric psychopharmacology. In: Crook T., Ferris S., and Bartus R. (Eds). Assessment in Geriatric Psychopharmacology (1983), Mark Powley Assoc., New Canaan 153-165