Selecting an "orthogonal" column during high-performance liquid chromatographic method development for samples that may contain non-ionized solutes

Journal of Chromatography A

Volumn 1216, Issue 16, 2009, Pages 3467-3472

  Dolan, J W ^a   Snyder, L R ^a  

^a LC RESOURCES   (United States)

Author keywords

Column selectivity; Hydrophobic subtraction model; Orthogonal column; Reversed phase selectivity

Indexed keywords

CATION EXCHANGES; CHROMATOGRAPHIC METHODS; COLUMN SELECTIVITY; HYDROPHOBIC-SUBTRACTION MODEL; ORTHOGONAL COLUMN; ORTHOGONALITY; REVERSED-PHASE SELECTIVITY; SEPARATION CONDITIONS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY;

SEPARATION;

1 NITROPROPANE; ACETOPHENONE; ANISOLE; BENZENE; BENZENE DERIVATIVE; BENZOPHENONE; BENZYL ALCOHOL; BIPHENYL DERIVATIVE; CAMPHORQUINONE; CHALCONE; COUMARIN; CYCLOHEXANE DERIVATIVE; EUGENOL; FERROCENE; FLUNITRAZEPAM; FLUORESCAMINE; HYDANTOIN DERIVATIVE; HYDROCORTISONE; LACTONE DERIVATIVE; MEPHENYTOIN; N,N DIMETHYLACETAMIDE; NAPHTHALENE DERIVATIVE; NITROBENZENE DERIVATIVE; OXAZEPAM; PARA XYLENE; PHENOL DERIVATIVE; PREDNISONE; STEROID; TOLUENE; TOLUENE DERIVATIVE;

ARTICLE; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; HYDROPHOBICITY; IONIZATION; LIQUID CHROMATOGRAPHY; MODEL; PH; PRIORITY JOURNAL;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IONS; ORGANIC CHEMICALS;

EID: 62949132156     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.08.039     Document Type: Article

References (17)

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16. PQRI database on the USP website: http://www.USP.org/USPNF/columnsDB.html.
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