The annexin-V assay reflects susceptibility to in vitro membrane damage in chronic lymphocytic leukemia and may overestimate cell death

American Journal of Hematology

Volumn 84, Issue 3, 2009, Pages 196-197

  Groves, Michael J ^a   MacCallum, Stephanie ^a   Boylan, Michael T ^a   Coates, Philip J ^a   Tauro, Sudhir ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOCORTIN 5; PROPIDIUM IODIDE; VIMENTIN;

APOPTOSIS; CELL DEATH; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; LETTER; MEMBRANE DAMAGE; PRIORITY JOURNAL;

AGED; ANNEXIN A5; APOPTOSIS; FEMALE; FLOW CYTOMETRY; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED;

EID: 62949113444     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.21347     Document Type: Letter

References (3)

1. Messmer BT, Messmer D, Allen SL, et al. In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J Clin Invest 2005;115:755-764.
2. Koopman G, Reutelingsperger CP, Kuijten GA, et al. Annexin-V for flow cytometric detection of phosphatidylserine expression of B cells undergoing apoptosis. Blood 1994;84:1415-1420.
3. Nowakowski GS, Hoyer JD, Shanafelt TD, et al. Using smudge cells on routine blood smears to predict clinical outcome in chronic lymphocytic leukemia: A universally available prognostic test. Mayo Clin Proc 2007;82:449-453.